Chemotherapy and ionizing radiation are known to promote clonal hematopoiesis and its progression to leukemia. By inducing temporary quiescence of hematopoietic stem cells during external stress might we mitigate CH expansion? We address this through a collaboration with @AbdelWahablab@PuZhang09980432: https://t.co/DUExKVNRSg. Excited to share this and some thoughts from a recent meeting in Hiroshima which puts this work in a broader perspective.
Excited to share our new article in @LeukemiaJournal on the prevalence and prognostic impact of myelodysplasia-related features in #VEXAS.
A nationwide effort from the French FRENVEX network 🇫🇷
https://t.co/WPUWBYd8ja
We're glad to share this article published in @Hemasphere_EHA showing that mutations in IDH (IDH1/2) can act as drivers of inflammation. https://t.co/FzIW6x12kK
American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS - Developed by the International VEXAS Working Group Expert Panel
Figure: A practical treatment algorithm for clinical management of VEXAS syndrome based on current available evidence
Thrilled to share our study with Vincent Jachiet and the FREnVEx group 🇫🇷on azacitidine efficacy in VEXAS syndrome, now published in @BloodJournal #VEXAS#Hematology#Azacitidine#FREnVEx#mds
https://t.co/Kh9aWbGeNZ
Ravi de partager le post-@EHA_Hematology que nous avons fait sur invitation de Sylvie Le Gac pour Cancérologie Pratique, avec @pedrohlprata, Tristan Vaugeois et @LinPierreZhao !
Vidéo disponible jusqu'au 31/07.
https://t.co/p5hOS8cBtC
1/ Excited to share our study with @kcw00d and @MartinCNRS on AML's dependency on PI3Kg, aligned with findings from @lane_andy and Zhao labs. It links to Venetoclax sensitivity and shows the promise of degradation over inhibition to enhance cytotoxicity. https://t.co/Izl4MMx0Q5
On this first day of the first ever #VEXAS international workshop, very happy to share our work on the Efficacy and Safety of targeted therapies in VEXAS syndrome!!
https://t.co/Vn64mqRfIz
Our article is finally out in @LancetDigitalH
https://t.co/TNSlFV2wqW
--> Diagnosis of acute leukaemia subtypes (APL/AML/ALL) based on routine laboratory parameters using machine learning
The model is broadly available in an online-app: https://t.co/xvlvweqkLt
C'est la 1ère fois que j'entends un Président de la République parler aussi précisément des externes et des internes en médecine. Et il a raison. Les étudiants et les internes participent à faire tourner l'hôpital. Ils sont pleinement engagés comme soignants. Ne les oublions pas.