Luis I. Prieto

Husband/ Dad/ Postdoctoral Fellow at Mayo Clinic interested in aging, cancer, and genetic variants that alter the immune profile

[Luis I. Prieto @LuisIPrieto1]

I am thrilled to share our latest study just published in @Cancer_Cell! We found that senescent cells, specifically senescent macrophages promote tumor growth by adjusting the local microenvironment.
https://t.co/LY9vgqtivH

[Nature Rev Immunol @NatRevImmunol]

Macrophages are constitutive architects of tissue integrity https://t.co/QG4QCjUJV6

[Luis I. Prieto @LuisIPrieto1]

Why some lung tumors respond well to immunotherapy.
https://t.co/Rvjdouoyy2

[Luis I. Prieto @LuisIPrieto1]

Very excited to share new work led by the Fields lab with our team contributing to this exciting discovery.
This study shows that senescent tumor cells actively induce the formation of tertiary lymphoid structures (TLS) in PRKCi-deficient lung adenocarcinoma.

[Cell Reports @CellReports]

Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma https://t.co/shPeFPHUVx

[Cell Reports @CellReports]

Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma https://t.co/shPeFPHUVx

[Nature Reviews Cancer @NatureRevCancer]

ICYMI 🚨

In this month's #Focus issue on #AgeingandCancer, de Magalhães explores the evolutionary relationship between cancer & ageing, proposing that the need to minimize cancer risk early in life may contribute to tissue degeneration later.

📖 👇
https://t.co/NRvx5eduZO

[Nature Reviews Cancer @NatureRevCancer]

ICYMI 🚨

In this month's #Focus issue on #AgeingandCancer, McAllister & colleagues discuss recent insights derived from age-resolved immunoprofiling of the TME and how ageing haematopoiesis affects immune cells and cancer progression.

#REVIEW 📖 👇
https://t.co/iA52GRrLhW

[Matthew D. Park, PhD @MatthewD_Park]

Our new perspective piece in @NatureAging from lab of @MiriamMerad @SinaiImmunol highlights the fundamental role for aging-related changes to resident tissue macs and myelopoiesis in both healthy aging and in cancer:

https://t.co/6E6hIDQhw5

[Nature Aging @NatureAging]

🎉 We’re thrilled to present our August issue, which includes a Focus on immune aging! 🎉Here, you’ll find a series of reviews and opinion pieces on recent advances in immune aging research https://t.co/ndA5WSSC9k 🎨by Alex Whitworth

[Nature Reviews Cancer @NatureRevCancer]

NEW content online! Ageing, immune fitness and cancer https://t.co/NrZCHkLNLq

[Diego A. Díaz-García @diegoadiazg]

🫁 Tumour–microenvironment crosstalk in #NSCLC drives resistance, metastasis, and outcomes.

Understanding spatial niches, inflammation, and immune evasion can reshape treatment strategies.

📖 @NatRevClinOncol
👉 https://t.co/VFjfHbOF9y

#CánCare #immunotherapy #biomarkers #lcsm

[Nature Reviews Cancer @NatureRevCancer]

#Review 🚨
Henry & DeGregori discuss models and methods used to study the connection between ageing and cancer, advocating advocating for the wider adoption of age-appropriate models of cancer to improve clinical translation
📖⬇️
https://t.co/ExALWRlnKk
@CUSystem

[Nature Reviews Cancer @NatureRevCancer]

While progress has been made in treating #NSCLC, patients would further benefit from earlier detection & interception. Here, Spira & colleagues explore advances in identifying premalignant lesions, & devise approaches for stratification + interventions.

https://t.co/4RNiT0PoS5

[Immunity @ImmunityCP]

Everything everywhere all at once: Unraveling the waves of aging https://t.co/JB0rPVt27t

[nature @Nature]

Nature research paper: Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours https://t.co/v12ZbbVxFU

[Cancer Cell @Cancer_Cell]

Myeloid effector cells in cancer https://t.co/g6MK7hqhsW

[Nature Reviews Cancer @NatureRevCancer]

NEW content online! Defining precancer: a grand challenge for the cancer community https://t.co/sKniwJ0Gn8

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

Registration open for this meeting for a bit longer. A few spots left https://t.co/9XtLzURSy4 Submit an Abstract and present a Short Talk or Poster. This is a small meeting, so a great networking opportunity w/ great speakers. Please circulate.

[Mayo Research Fellows’ Association (MRFA) @MayoMrfa]

Thank you everyone for joining us at our first Thursday seminar last week! Big thanks to Dr. Prieto @LuisIPrieto1 for sharing his research on Cancer and senescent cells. We were also pleased to introduce the new team at MRFA.

What topics would you like to hear about next Month?

[SenesceX @SenesceX]

Fantastic work from @naritalab ! Many congratulations to @adelynechan, Masashi and all involved.

https://t.co/fCZrjcPElC

[Nature Aging @NatureAging]

Online now!✨RESEARCH: @JPCastro_Aging, Shindyapina et al explore how aging promotes B-cell lymphoma in mice, identifying a population of age-associated clonal B cells that drive malignancy https://t.co/LUO8Z67fDN https://t.co/x3JEUapfND