MDRC_CRDM

Montreal Diabetes Research Center @CRCHUM 58 teams @UMontreal @McGillU @UQAM @USherbrooke @universitelaval @uOttawa studying diabetes, obesity & complications.

[News from Science @NewsfromScience]

Svetlana Mojsov helped discover the hormone GLP-1, which led to the development of blockbuster obesity drugs. Now, she’s fighting for recognition. #LongReads https://t.co/OiztSK71z6

[Elite Possik @elite_pk]

Excited to share our latest paper published in Nature Communications about the mechanism whereby overexpression of G3PP protects from gucotoxicity and promotes healthy aging in C.elegans. New from the Prentki Lab! @MDRC_CRDM
https://t.co/xf49xbygQ5

[Christian Wolfrum @WolfrumLab]

I disagree with this suggestion. Research is based on failure. Those who finance research have to take this risk without the prospect of a direct return on investment. Such approaches endanger basic research not just at @ETH but worldwide.
https://t.co/R5qEBzlV47

[MDRC_CRDM @MDRC_CRDM]

@guy_rutter @ADA_DiabetesPro Great to have debate. But at max glucose concentration is not the right one to test the model. Sub maximum are much more revealing to discuss canonical mito versus PK control. Marc Prentki

[Nature Metabolism @NatMetabolism]

Online now! Triglyceride cycling enables modification of stored fatty acids https://t.co/VWPnQe7wtE

[MDRC_CRDM @MDRC_CRDM]

@DanielJDrucker May be as we discussed glp. Eat less. Less fat and glucolipotoxicity metabolic stress in the heart less cardiomyopathy and MACE. No need glpr in the heart for this Obesity with T2D known to be associated with some steatosis in the heart Marc

[Daniel J Drucker @DanielJDrucker]

A refined model of fuel signals and cycles driving #insulin secretion #islets #diabetes @bcorkey @MDRC_CRDM @Cell_Metabolism https://t.co/Ad0qeA8HU0

[Matthew Merrins @merrinslab]

Excited to share our review in @Cell_Metabolism proposing a revision to the canonical beta cell model that incorporates spatial metabolic signaling. A great collaboration with @bcorkey, Dick Kibbey, and Marc Prentki. Thanks to @guy_rutter and many others. https://t.co/bzERJjbA7r

[Daniel J Drucker @DanielJDrucker]

“We propose that that the glycerol shunt plays a role in preventing
#insulin hypersecretion and excess body weight gain and contributes to ß-cell mass preservation in mice in the face of hyperglycemia” New from the Prentki lab @MDRC_CRDM @MolMetab https://t.co/ULgw1xiWpu

[Elite Possik @elite_pk]

Very happy to share our work published in @NatureComms about a new calorie restriction mimetic enzyme that promotes healthspan and protects from glucotoxicity in C.elegans. @marcprentki @JAlexParker @CRCHUM
@udem
@MDRC_CRDM @rrcmdo
https://t.co/btqZuLXxXY
https://t.co/btqZuLXxXY

[Daniel J Drucker @DanielJDrucker]

“We propose that G3PP in beta cells acts as a security valve that expels excessive glucose carbons as glycerol to prevent excess secretion of insulin, ß-cell dysfunction and death under chronic hyperglycemic conditions” #diabetes @MDRC_CRDM https://t.co/JeVo6cnQou

[MDRC_CRDM @MDRC_CRDM]

@philippefroguel Il n y a pas de peuple pire ou meilleur qu un autre ce qui n est pas le cas de ceux qui les gouvernent. N oublions pas que les premiers à être dans des camps en 1933 en Allemagne étaient des allemands Les autrichiens ont ils voté pour l Anchluss? On connaît la réponse Marc

[MDRC_CRDM @MDRC_CRDM]

@JuleenRZierath @EASDnews @srp_diabetes @Metabolcenter Congrats Juleen and team for great work. Marc Prentki

[MDRC_CRDM @MDRC_CRDM]

@Mathieu_Ferron I keep wonderful memory of myrtella Such nice human being. She always helped CDA committee member doing best job. We will miss her and her smile. Marc Prentki

[MDRC_CRDM @MDRC_CRDM]

@Mathieu_Ferron I keep wonderful memory of myrtella Such nice human being. She always helped CDA committee member doing best job. We will miss her and her smile. Marc Prentki

[Mathieu Ferron @Mathieu_Ferron]

This is a very sad news. So sorry.

[HoesliLab @HoesliLab]

We just posted our postdoctoral fellow position on cellular therapy & immunotherapy on Nature Jobs. The project is in collaboration with @SG_LifeSciences
and Kanyr Pharma in Montreal. Last chance to apply! #postdocjobs #Immunotherapy #cellulartherapy

https://t.co/FCJtXieaPG

[Lawrence Kazak @kazaklab]

1/ Today in @nature, our lab details the discovery of a key effector protein that controls the futile #creatine cycle in #brownfat #thermogenesis. https://t.co/qipY0xdBv1. @mcgillGCRC, @mcgillmed, Karen Reue @UCLA and Bruce Spiegelman @DanaFarber. Tweetorial below…

[Molecular Metabolism @MolMetab]

The free #fatty #acid #receptor 4 regulates #hormone #secretion in the #pancreas via expression in the delta-cells of the islet.
@VPoitout @CRCHUM @MDRC_CRDM

➡️https://t.co/LIOZiZBDAV

[MDRC_CRDM @MDRC_CRDM]

Thrilled to welcome you @guy_rutter & Dr Isabelle Leclerc in Montreal & @MDRC_CRDM A strong gain for beta-cell & diabetes research in Montreal, Québec & Canada, exciting ! @rrcmdo @CIRTNetwork

[Guy Rutter1 @guy_rutter]

Delighted and privileged to announce that I’ll be joining @VPoitout @AlquierThierry and col at @CRCHUM as Professor of Medicine at l’Universite de Montréal, Québec 🇨🇦 from August 2021. Post doc positions in beta cell biology and functional genomics available!