Major alcohol study just released (after unexplained delay from HHS):
Even 1 drink per day linked to higher risks of serious illness & premature death - including liver cirrhosis, certain cancers, and injuries. No net health benefits found at any level.
This taxpayer-funded review adds to evidence that alcohol harms start low. It’s sparking fresh questions about past U.S. dietary guidelines and potential industry influence.
Key takeaway: Less is better for long-term health! https://t.co/Xq1Q5BV2u3
Meta-analysis of digitalis glycosides in HFmrEF or HFrEF indicated reduced risk of worsening #HeartFailure events, with no difference in mortality, across multiple randomized trials.
https://t.co/lZMrggrAvm
In this scientific statement, we
💢address the multidimensional needs of older adults w/ #HF, paying attention to multimorbidity, frailty, goals of care
💢discuss strategies to ⬆️uptake of #HF drug & device Txs that improve outcomes but are underused in👵🏼
https://t.co/dBd5920YzM
HIF-2 drives coronary inflammation, remodeling, and thrombosis in a novel mouse model recapitulating Kawasaki disease. Pharmacological HIF-2 targeting may be a new therapeutic strategy for coronary vasculitis. https://t.co/BvBGjXCdpS
#HFpEF is no longer defined by unmet need, evidence-based therapies are here and they're changing practice 🫀
Dr @hvanspall hosts this Masterclass with Prof @MajaCikes, unpacking the trial evidence reshaping HF management – from SGLT2 inhibitors & non-steroidal MRAs to phenotype-driven care in obesity-related HFpEF
Key trials: EMPEROR-Preserved, DELIVER, TOPCAT, FINEARTS-HF, STEP-HFpEF, SUMMIT + a look ahead to HF-POLARIS and MARITIME-HF
Watch video + slides here https://t.co/Rh3icRkpn9
#CardioX #HeartFailure #HFpEF #HFmrEF #SGLT2 #Cardiology #CME
#echofirst
✅ Time to close. 🙏 for comments
✅ Unusual PW Doppler from PV showing a brief reversal prior to the usual P wave related reversal (Ar)
✅ This is not an artifact since it was reproducible, gain setting was OK etc ⬇️
✅ During later part of diastasis here there was a brief period when LV diastolic pressure exceeded LA pressure
✅ Is this an unusual finding indicative of ⬇️ diastolic LV compliance? Stiff LA?
@echo_batman@argulian@EchoSoliman@strain_rate@iamritu@BryanTanMD@HeartOTXHeartMD@purviparwani@JaeKOh2@SNagueh
Blood #aldosterone concentrations and effects of #MRA in #HeartFailure
Pooled analysis of 1,019 HF patients (DOSE, CARRESS-HF, MDR, #TOPCAT) showed #MRA benefit was dependent on baseline aldosterone: high aldosterone predicted improved outcomes (HR 0.63), while low aldosterone was associated with worse outcomes (HR 1.66
https://t.co/lXALZ6qjOU
#EHJ @ESC_Journals@markcpetrie20@ehj_ed@EJHFEiC@MarcoMetra
Mitral Valve Anatomy: Leaflets, Annulus, and Subvalvular Apparatus
👉The mitral valve is an integrated unit: saddle annulus, anterior and posterior leaflets, commissures, chordae, and papillary muscles.
👉Posterior scallops P1–P3 oppose anterior segments A1–A3, with fibrous aorto-mitral continuity anchored by both trigones.
👉Primary chordae support leaflet edges, while secondary chordae and two papillary muscle groups stabilize coaptation and LV geometry.
A patient came in with shortness of breath.
Then the X-ray loaded 😭
And it looked like someone had left a sword inside the chest.
Quick diagnosis challenge 🩻
What’s the most likely diagnosis?
Wild guesses are welcome 👀
Prof @jhfrudd masterfully leads a podcast on #HFpEF & #AF
Have a listen on your work commute or workout!
https://t.co/Edhg7YwP59
Podbean: https://t.co/qyn95A0LE6
Apple Podcasts: https://t.co/gNAkd7Fwi0
Spotify: https://t.co/tuJ7ZYFXm1
Amazon Music: https://t.co/mpECs0ljgd
Severe post COVID myocarditis, free TR, mod MR, massive ascitis and pleural effusion, small pericardial effusion, look at the mobile masses, do you know what this is?
We are delighted to welcome Dr @CarlChiefCard back to McMaster to present at our Regional Grand Rounds.
#PVCs: the good, bad, and ugly
Tuesday Jun 9
8 am EST
On your Teams link
🔑Key Takeaways on MVP, MR, MAD & Arrhythmic Risk 🫀 #ASEchoJC
✅ MVP affects ~2.5% of the population and is the leading cause of primary MR.
✅ Diagnosis requires ≥2 mm leaflet displacement in the PLAX/long-axis view.
✅ Barlow’s disease ≠ FED:
• Barlow = redundant bileaflet prolapse
• FED = isolated segment prolapse with chordal rupture
✅ MR assessment is tricky—eccentric, multiple, commissural, and late-systolic jets can underestimate severity.
✅ Not all MAD is created equal:
True MAD persists in systole and diastole; pseudo-MAD does not.
✅ MAD and prolapse volume add to LV volume overload beyond MR alone.
⚠️ Arrhythmic MVP can occur even without severe MR.
🚩 Echo markers of increased VA/SCD risk:
• Bileaflet prolapse
• MAD >8.5 mm
• Pickelhaube sign
• Curling
• Mechanical dispersion
• Double-peak strain pattern
🎯 CMR is critical for risk stratification—fibrosis by LGE or elevated ECV identifies patients at higher arrhythmic risk.
See you next #ASEchoJC!
@PWesslyMD@HeartToProve@LucySafi@CASivaram1@iamritu@purviparwani@ASE360@JournalASEcho