MikaelScience

Scientist in @TheBlanchardLab.
I like ribosomes.

[Scott C Blanchard @TheBlanchardLab]

Excited to share our Annual Reviews in Biophysics article on Single-Molecule Imaging of Integral Membrane Protein Dynamics and Function. Many thanks to all authors for their diligence putting this summary overview together! https://t.co/bbuuJJnkWF

[Nature Methods @naturemethods]

Out today from the Blanchard lab! An important paper showing that the accuracy of smFRET measurements depends on excitation strength, and how to correct for these issues or bypass them with self-healing dyes. https://t.co/2dpO9NU5lE

[MikaelScience @MikaelScience]

@IsraelF96135088 Nah, these Everest guys aren't stabbing each other to be the first to the top :)

[MikaelScience @MikaelScience]

@IsraelF96135088 Looking at fig. 3a, maybe you should be a little worried @IsraelF96135088 😂

[Tominaga K. (tomiken) @pacyc1841]

» Ribosome-binding antibiotics increase bacterial longevity and growth efficiency | PNAS https://t.co/dW1FbxuCAM

[DNA&RNA Universe 𝕏 @DNA_RNA_Uni]

High resolution Molecular dynamics (MD) of mRNA translation on ribosome

[Vasili Hauryliuk @hauryliuk]

It is out in @PNASNews. A massive bioinformatics undertaking by @gem__atkinson lab + an insane amount of experiments from my team and numerous collaborators. The first new phage defence system from Lund! @HenrikStrahl @arneelof @KarinErnits @FacultyLund https://t.co/x6cH8Upbfx

[Suparna Sanyal @sanyal_suparna]

Happy to share that Mathew Gagnon and my lab's joint story of translation inhibition by aminoglycoside Amikacin is now published in @NatureComms 🥳🥳🥳. Superhappy for this collaboration. Fast-kinetics biochemistry and structure together make a very powerful tool afterall 😃

[Sergey Melnikov @SergeyVMelniko1]

Our study shows that ribosomal genes—widely used to infer the origin of species—also hold a record of the optimal growth conditions for a given species, making it easier to infer the optimal environment for uncultured or extinct organisms (1/3): https://t.co/kWLU8vpcQe

[Matthew L. Kraushar @MatthewKraushar]

check out our Spotlight Article @TrendsGenetics
🔥 hot 🔥 off the press!

teamed up with @OlivierDuss (@EMBLHeidelberg) & @RainerNikolay (@MPI_MolGen) to cover the recent mRNA decoding ribosome smFRET🤝cryoEM story from @TheBlanchardLab

open access 👇
https://t.co/fxq2IjTQdk

[Olivier Duss @OlivierDuss]

In our new Spotlight in @TrendsGenetics we are discussing the recent @Nature paper from @TheBlanchardLab about eukaryotic mRNA decoding combining smFRET and cryoEM!

Was fun to collaborate with & @MatthewKraushar & @RainerNikolay @MPI_MolGen on this!
https://t.co/Y0NkBMsAgE

[Israel Fernandez @IsraelF96135088]

We suffered two problems on our Krios/Arctica instruments related to a pressure gauge called PPal. Here a picture of the faulty PPal from the Arctica. But then...what is a PPal and how it measures pressure? These two questions kept me busy for a while, a thread to follow 👇

[Israel Fernandez @IsraelF96135088]

Very soon and thanks to one an only @delarosatrevin an integrated solution for CryoEM facility management and on-the-fly processing with Cryolo/ctfffind/Relion ! And free!!! 👇🏽
Look at these gorgeous ribosome from @TheBlanchardLab !

[Ignatova Lab @IgnatovaLab]

Happy to anounce our paper published today ⁦@Nature⁩ - a tour-de-force in tRNA biology. We developed suppressor tRNAs with high efficieny in correcting PTCs. For a disease protein we crossed a disease threshold of correction. #cftr #uhh https://t.co/sr0CHUlIMJ

[alexmag @AlexmagCryo]

Proud to be involved in this work. Please have a look. High res.80S ribosome, many states, interesting story.
@TheBlanchardLab @AlexmagCryo
@KundhavaiS
https://t.co/c5Ug92JjvZ

[News Medical @NewsMedical]

Is mRNA decoding in humans structurally and kinetically distinct from bacteria? https://t.co/zmR4ZYQDKg @Nature @StJudeResearch #mRNA #bacteria #molecularbiology #research #bacteria #microbiology #cells #news

[cryoEM Papers @cryoEM_Papers]

Mechanism of messenger-RNA decoding in humans illuminated https://t.co/haw5DpTwSF

[Structural Biology at St. Jude Children's Hospital @StJudeStructBio]

See also Research Briefing here:
https://t.co/nqk5nUY7Po
Congrats @TheBlanchardLab @MikaelScience @ERundlet @KundhavaiS and all authors!

[Structural Biology at St. Jude Children's Hospital @StJudeStructBio]

Now #OA @Nature: combining #cryoEM and #smFRET to examine decoding by human #ribosome, @TheBlanchardLab reveals important differences from bacterial ribosome and mechanisms of action of several translation inhibitors.
https://t.co/rMVrLUg5o9

[St. Jude Research @StJudeResearch]

Human ribosomes decode messenger RNA 10 times slower than bacterial ribosomes—but do so more accurately. Explore how St. Jude scientists made this discovery. https://t.co/IhU9QII1sE @TheBlanchardLab @nature #cryoEM