Nicole Bender

Derm-Dermpath at Sagis Diagnostics
The views expressed on this website are mine alone and should not be considered medical advice.

[Nicole Bender @NRBenderMD]

@MELanocyteMD @HENRYY_MD @Gloria_SuraMD @DrAldehyde @MightyDermPath @TristanRutland7 @AhmedShahMD @SumantaDas_7 @PathBst @SimonRoyMD Nice example 😍😍

[Melanie Bourgeau, MD @MELanocyteMD]

Localized Tenosynovial Giant Cell Tumor:
1️⃣ Multilobulated, dense fibrosis
2️⃣ Mononuclear neoplastic cells (epithelioid/plasmacytoid)
3️⃣ Variable GC's, foamy histiocytes, hemosiderin

Learn more:
✳️ https://t.co/xNqKnCrrHP
✳️ https://t.co/s7AgGqgDfp

#3thingstoknow #bstpath

[Nicole Bender @NRBenderMD]

And finally Silicone
These are empty lipid-like vacuoles, variably sized, within histiocytes. You frequently need history to help inform you to make this diagnosis, as some artifact can mimic these changes

[Nicole Bender @NRBenderMD]

50s F cheek - clinical ddx: cyst vs. foreign body rxn
- pt had history of soft tissue augmentation
#dermpath #pathtwitter #dermtwitter #pathology #dermatology #residenteducation
#backfromsummerhiatus

[Nicole Bender @NRBenderMD]

Calcium Hydroxylapatite (Radiesse)
This is very distinctive, with grey-green granular microspheres. These microspherules are not refractile under polarizable light.

[Nicole Bender @NRBenderMD]

@PathologoP Tissue culture-like fibroblasts resemble those grown in the lab on plates. They are stellate and elongated with finely tapered ends (which adhere to the dish or plate).

[Nicole Bender @NRBenderMD]

80sM - neck/shoulder area - clinical ddx: Lipoma
#pathology #PathTwitter #dermatology #dermtwitter #dermpath #residenteducation #tweetorial

[Vikram Deshpande @Vik_deshpandeMD]

First of 4 videos on what may be called Ewing Family of Tumors. This is Ewing #BSTPath PS I'm so old that I remember using PAS and PAS/D to make a diagnosis of Ewing😱

[Nicole Bender @NRBenderMD]

@94_inno @JMGardnerMD @DrGeeONE @TristanRutland7 Pretty! Agree myofibroma :)

[Nicole Bender @NRBenderMD]

Ddx: Rhabdomyosarcoma
- Desmin+, polygonal cells w/ more eosinophilic cytoplasm & more severe cytologic atypia + atypical mitoses, may contain cross-striations
- proliferative fasciitis usually has mitoses, but should not have ATYPICAL mitoses
- also wrong pt characteristics

[Nicole Bender @NRBenderMD]

Ddx: Nodular fasciitis
- does not contain these characteristic ganglion-like cells

Ddx: Ganglioneuroma
- S100+, contains Schwann cells, fibrillar background lacking significant component of fibroblasts/myofibroblasts & wrong pt (too old + this tumor not really seen in skin)

[Nicole Bender @NRBenderMD]

@Madhury57496817 @MELanocyteMD Great call!