Overacre Lab

Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own

[Overacre Lab @OveracreLab]

I am thrilled to finally share my lab's first paper showing that sucralose consumption reduces immunotherapy efficacy in cancer, published NOW in @CD_AACR ! Let's break it down. 1/n
https://t.co/B85rLv9HDD

[Delgoffe Lab @DelgoffeLab]

Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ https://t.co/zACqCLxDMU

[UPMC Hillman Cancer Center @UPMCHillmanCC]

Congratulations Dr. Finn, an amazing immunologist who continues her research on vaccines at UPMC Hillman & the University of Pittsburgh! @pitt_immunology @PittHealthSci @UPMCnews @UPMCPhysicianEd

[Pitt Department of Immunology @pitt_immunology]

Congratulations to Drs. Dario Vignali @Vignali_Lab and Sarah Gaffen (@PittDeptofMed, @PittRheum) on being recognized as 2026 Distinguished fellows yesterday at @ImmunologyAAI #IMMUNOLOGY2026!

[Overacre Lab @OveracreLab]

Had a fantastic time at the Case CCC Microbiome Conference! Thanks for the invite @nataliesilvermd - what an inspiring event!

[Overacre Lab @OveracreLab]

A belated but very happy 4th birthday to the lab 🎉 so thankful for such an awesome crew! Here’s to many more years of science and fun.

[Pitt Department of Immunology @pitt_immunology]

Diet soda could be sabotaging cancer treatment. Exercise could be boosting it. It all comes down to the gut microbiome. @PittHealthSci and @UPMCHillmanCC researchers are figuring out how to harness gut bacteria and protists to improve cancer outcomes: https://t.co/7BQpePZfMK

[Pitt Department of Immunology @pitt_immunology]

Next up in our trainee spotlight series is Katelyn Wolfgang (@Kate_Wolfgang), a graduate student in the @OveracreLab who studies how a commensal gut bacterium drives the formation of tertiary lymphoid structures in the colon: https://t.co/FJZWOyVBeP

[Iwijn De Vlaminck @IwijnDeVlaminck]

New paper in @NatureMicrobiol.

Spatial RNA mapping of microbiome and host. In situ polyadenylation is the key idea. More to come on this.

Thank you @NIH and @weandmecfs.

https://t.co/QH1U6OnNVo

[Overacre Lab @OveracreLab]

Honored to be part of this @UPMC Cancer Prevention and Survivorship Symposium today!

[Overacre Lab @OveracreLab]

An incredible study, congrats all!

[Waggoner Lab @LabWaggoner]

Spatial transcriptomics maps host–gut microbiome biogeography at high resolution
https://t.co/xGdrkJysKN
@NatureMicrobiol @dwmckellar @ntekasi @IwijnDeVlaminck @Cornell

[Overacre Lab @OveracreLab]

We also had great representation by @Kate_Wolfgang_ and @sadhanabom in the lab!

[Overacre Lab @OveracreLab]

Congrats to @jessica_jana_ and Kelsey Ertwine for receiving @ImmunologyAAI awards at @TRCCC1998 this year!!

[Overacre Lab @OveracreLab]

I got to share some new work in the lab during the Microbiome Emerging Science Working Group

[Overacre Lab @OveracreLab]

The lab had a great time @TRCCC1998 this year!

[Overacre Lab @OveracreLab]

Congrats to @ItzDipyaman for being selected for a SITC sponsored talk where he talked about Tregs and irAEs!

[Overacre Lab @OveracreLab]

Honored to be featured by @DamonRunyon this year!

https://t.co/kO2bX5sghe

[Overacre Lab @OveracreLab]

Love being a part of this! Thanks for including me @JExpMed !

[Lucie Van Emmenis @Lucie_JExpMed]

As 2025 is drawing to a close, @JExpMed would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 https://t.co/WZeOWtF5dQ

[Overacre Lab @OveracreLab]

So thankful for this crew! Missing a couple folks, but we got out of the lab for some cheer tonight!

[Overacre Lab @OveracreLab]

Incredibly proud PI today after @Pitt_PMI day! My three incredible students presented their work and helped to organize an awesome event! @jess_jana_ @Kate_Wolfgang_

[Pitt Department of Immunology @pitt_immunology]

On the latest Outperform Cancer podcast, @OveracreLab chats with @marybethgilliam about her new research showing that the artificial sweetener #sucralose weakens #immunotherapy effectiveness by disrupting the #microbiome https://t.co/DJXHxd0BGM