Pragmatic Critical Care Research Group

Improving the care of critically ill adults by studying common critical care practices in the environment in which they occur

[Critical Care Reviews @CritCareReviews]

@JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simultaneously published in @NEJM

https://t.co/4Awp1u7axg
@PCCRG

[Pragmatic Critical Care Research Group @PCCRG]

Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/6cOLnQtaC2

[Adit Ginde @AditGinde]

Excited to share practice-changing results of our PREOXI trial showing preoxygenation with non-invasive ventilation safely reduced hypoxemia by 51% during emergency tracheal intubation @PCCRG @CUEmergency @CUCombatCenter
#CCR24
https://t.co/bJzaB0otgs

[Pragmatic Critical Care Research Group @PCCRG]

Next up from the ⁦@PCCRG⁩ https://t.co/8dxjXzcqbP

[Pragmatic Critical Care Research Group @PCCRG]

https://t.co/ZsNWhJe3Pp

[Critical Care Reviews @CritCareReviews]

Miss the @PCCRG DEVICE trial, presented by Matthew Semler & Matthew Prekker at the Critical Care Reviews Meeting #CCR23 last week?

It was simultaneously published in @NEJM
https://t.co/3MobsWJfmh

Here, the trialists briefly explain the results

[ICUEdandToddCast @IcuCast]

Off schedule but super excited to have the opportunity to sit down with Matt Prekker from the @PCCRG who just presented the DEVICE trial published in @NEJM today and presented at the @CritCareReviews meeting 2023

DEVICE: https://t.co/czd7zvCpuZ

[Pragmatic Critical Care Research Group @PCCRG]

Result now online @NEJM

https://t.co/VVhyR0biP6

[Pragmatic Critical Care Research Group @PCCRG]

Coming up in a few minutes, Matt Prekker and Matt Semler present the #DEVICEtrial at #CCR23. The ⁦@PCCRG⁩ conducted the largest randomized trial of video vs direct laryngoscopy in critically ill adults. Answer to this question in a few minutes https://t.co/OQVA4PykPM

[Pragmatic Critical Care Research Group @PCCRG]

Individualized Treatment Effects of Bougie versus Stylet for Tracheal Intubation in Critical Illness | American Journal of Respiratory and Critical Care Medicine https://t.co/KiF1l7995U

[Pragmatic Critical Care Research Group @PCCRG]

https://t.co/b1DVyNJswv

[Pragmatic Critical Care Research Group @PCCRG]

Matt Semler currently presenting the PILOT trial results ⁦@CritCareReviews⁩ #CCR23 https://t.co/OQVA4PykPM

[Critical Care Reviews @CritCareReviews]

Our next faculty member for #CCR23 is Assoc Prof Matthew Prekker (Minneapolis, USA)

https://t.co/JP6c2O2Pq6

[Pragmatic Critical Care Research Group @PCCRG]

Out now in the ⁦@NEJM⁩, the next publication by the ⁦@PCCRG⁩ https://t.co/b1DVyNJswv

[Critical Care Reviews @CritCareReviews]

@DogICUma @VR_Cornelius @BodilSRasmussen @JonathanCaseyMD @toddrice_ICU @PCCRG The trial results are being freely livestreamed
Monday Oct 24th, 8pm UTC+1

Faculty includes chief investigators for

➡️PILOT
➡️O2-ICU
➡️HOT-ICU
➡️LOCO2
➡️ICU-ROX
➡️ongoing MEGA-ROX

https://t.co/46GjQG72L9

See you on Monday!

15/16

[Critical Care Reviews @CritCareReviews]

@DogICUma @VR_Cornelius @BodilSRasmussen @JonathanCaseyMD @toddrice_ICU Enter the PILOT trial from @PCCRG

➡️Pragmatic Investigation of optimaL Oxygen Targets
➡️2500 patients
➡️randomised cluster-crossover trial
➡️SpO2 90% v 94% v 98%
1⃣ outcome ventilator-free days at D28

14/16

[Critical Care Reviews @CritCareReviews]

The PREPARE II trial result presentation from #CCR22 is now available
https://t.co/7rX7fNoTnQ

Results - @DerekRussellMD @JonathanCaseyMD
Editorial - @agordonICU
Panel Discussion - @ADAlthousePhD @1791_mew @Lennie333 @LarsWAndersen1 @seymoc

Very impressive trial from @PCCRG

[Andrew Althouse @ADAlthousePhD]

3b. To deal with this uncertainty the @PCCRG is proactively (often with minimal resources...) running trials to address some "we do this every day without really knowing whether it's helpful or harmful" issues, like the PREPARE-II trial

https://t.co/xQ1JNF8nZj

[Pragmatic Critical Care Research Group @PCCRG]

#PREPAREII published in ⁦@JAMANetwork⁩ today and presented at #CCR22. Thanks to all of the ⁦@PCCRG⁩, ⁦@CritCareReviews⁩, ⁦@JAMANetwork⁩ to see this huge effort come to conclusion https://t.co/ZbivREyBN3