Pepito

🇮🇹#bitcoin #curiosity #learning #nature #exercise #intermittentfasting #freedom - Bad money-good life “JK”. Tell the truth-or at least,don't lie “JBP”.🇮🇹

[Pepito @PepitoPolak]

#Bitcoin is a swarm of cyber hornets serving the goddess of wisdom, feeding on the fire of truth, exponentially growing ever smarter, faster, and stronger behind a wall of encrypted energy.

[Dr. Rhonda Patrick @foundmyfitness]

Artificial light at night is a risk factor for age-related eye disease.

Evening light exposure above 1,000 lux was associated with a 31% greater risk of macular degeneration, an 18% greater risk of cataract, and a 47% greater risk of glaucoma.

1000 lux is very bright (e.g., a heavily lit television studio), but it illustrates the risks of nighttime light that may still be present at lower levels of exposure to screens or bright bedrooms.

[Pepito @PepitoPolak]

@Fidias0 What is the solution for that ?

[Alex @alexpilar]

Nejbohatší Ital už není výrobce kabelek, luxusních aut ani bankéř.

Je jím Giancarlo Devasini, spolutvůrce Tetheru. Deset let posloucháme, že Tether zítra zkrachuje. Mezitím stablecoiny přepisují finanční infrastrukturu světa.

To není příběh o Tetheru. To je příběh o tom, kam inovace přesouvá moc.

[Robert Chovanculiak @RChovanculiak]

Slovenskí zamestnanci dostávajú v čistom jedny z najnižších miezd v EÚ. Sme na 4. mieste od konca. Pred nami sú už len Rumunsko, Bulharsko a Maďarsko.

Slovenskí zamestnávatelia však platia cenu práce, ktorá je takmer v strede rebríčka EÚ. Platia rovnako ako českí zamestnávatelia a viac ako portugalskí, poľskí, maltskí, chorvátski, grécki, litovskí, lotyšskí, maďarskí, rumunskí či bulharskí.

Asi tušíte, kde sa stráca rozdiel medzi tým, čo odíde z vrecka slovenského zamestnávateľa, a tým, čo skončí vo vrecku slovenského zamestnanca.

Problémom nie je len nižšia životná úroveň, ale aj semienko konfliktu, ktoré vysoké daňovo-odvodové zaťaženie vytvára v spoločnosti. Zamestnanci majú pocit, že za svoju prácu nedostávajú adekvátnu odmenu, a zamestnávatelia majú pocit, že za vysokú cenu práce nedokážu vytvoriť dostatočnú pridanú hodnotu.

Tento konflikt je následne vodou na mlyn populistom a etatistom, ktorí nás posúvajú ešte ďalej nesprávnym smerom – k väčšiemu štátu. Je to také etatistické perpetuum mobile smerujúce k ekonomickému zaostávaniu a chudobe.

O tom, ako z neho vystúpiť, je kniha O pôvode prosperity (2025).

[Pepito @PepitoPolak]

Wtf is that…fix it…

[Pepito @PepitoPolak]

Fix the app @SumUp our clients need pay us!!!

[Brandon Luu, MD @BrandonLuuMD]

People told to track moments of gratitude reported fewer health complaints, exercised nearly 1.5 hours more per week, and felt better about their lives than people focused on the negative.

What you focus on becomes your reality.

[Pepito @PepitoPolak]

https://t.co/fS059x7k0U - @DaliborCicman - klobuk dole za myšlienky vo videu, z ktorých sa dá učiť a len súhlasiť.

[Nicholas Fabiano, MD @NTFabiano]

Instead of “I’m bad at this”.

Say “I'm new to this”.

This gives your brain the space to learn instead of shut down.

This is neuroplasticity in real time.

[Pepito @PepitoPolak]

Do you remember when you joined X? I do! #MyXAnniversary

[FoundMyFitness Clips @fmfclips]

People who end up happy and healthy in old age typically share 7 habits:

1) Healthy diet
2) Regular physical activity
3) No smoking
4) No substance abuse
5) Lifelong learning
6) A go-to technique for dealing with life's problems
7) Love through a strong marriage and/or close friendships

There's no substitute for the last one

Happiness is love, full stop

[Deep Psychology @DeepPsycho_HQ]

“ Politicians and Diapers must be changed often, and for the same reason.”

- Mark Twain.

[Learn Something @cooltechtipz]

Never do this to anyone. It can completely shatter someone’s confidence. 🙏😔

[vittorio @IterIntellectus]

this is actually insane

> be tech guy in australia
> adopt cancer riddled rescue dog, months to live
> not_going_to_give_you_up.mp4
> pay $3,000 to sequence her tumor DNA
> feed it to ChatGPT and AlphaFold
> zero background in biology
> identify mutated proteins, match them to drug targets
> design a custom mRNA cancer vaccine from scratch
> genomics professor is “gobsmacked” that some puppy lover did this on his own
> need ethics approval to administer it
> red tape takes longer than designing the vaccine
> 3 months, finally approved
> drive 10 hours to get rosie her first injection
> tumor halves
> coat gets glossy again
> dog is alive and happy
> professor: “if we can do this for a dog, why aren’t we rolling this out to humans?”

one man with a chatbot, and $3,000 just outperformed the entire pharmaceutical discovery pipeline.

we are going to cure so many diseases.
I dont think people realize how good things are going to get

[Tim Cook @tim_cook]

April 1st marks 50 years of Apple. Thank you to everyone who’s been a part of our journey. https://t.co/ZeB68ok859

#Apple50

[Perplexity @perplexity_ai]

Announcing Personal Computer.

Personal Computer is an always on, local merge with Perplexity Computer that works for you 24/7.

It's personal, secure, and works across your files, apps, and sessions through a continuously running Mac mini.

[Carnivore Aurelius ©🥩 ☀️🦙 @AlpacaAurelius]

guys, from 4-7pm every day, your testosterone tanks.

this is basically your man "period", your body is shedding the days work

you need to just chill out, your woman cannot ask anything from you and if anything she should bring you ice cream

[Bryan Johnson @bryan_johnson]

Overall, significant upgrade to the American diet. Some longevity tweaks:

0. Milk and dairy should be deprioritized and moved down the inverted pyramid, especially for adults. In adults, and particularly men, milk protein has an unfavorable amino acid composition, being high in Branched-Chain Amino Acids (BCAAs). BCAAs have been linked to metabolic disease and preclinically shown to accelerate cancer growth. BCAAs, especially leucine, are potent mTOR activators; while essential for growth, repair, and survival, mTOR hyperactivation accelerates aging and is a common mechanism underlying several chronic diseases.

Milk protein has been associated with inflammation, blood glucose dysregulation, and weight gain in some mechanistic and observational studies; however, randomized controlled trials show inconsistent effects. In a longevity-focused context, high dairy-derived BCAA intake may nonetheless contribute to metabolic stress, including impaired glucose handling and weight gain, in susceptible adults and is therefore best moderated.

Saturated fatty acids are another concern. The American Heart Association recommends limiting saturated fat to 5–6% of total energy (around 13 g/day at a 2,000 kcal intake) when targeting LDL reduction, which is particularly important for men over 40 and post-menopausal women, high-risk groups for cardiovascular disease, still the leading cause of death in developed societies including the US.

1. Legumes should have their own prominent category, placed high on the pyramid as a primary protein and dietary fiber source. Plant-based protein has been associated with better health and longevity outcomes in several large population studies across various societies, including the US. Legume fiber has health promoting qualities, including the reduction of colon cancer risk.

2. Meat belongs on the pyramid but with an emphasis on high-quality, non-processed sources. It should occupy a lower rank and be optional, especially for adult men. Red meat is associated with increased chronic disease and mortality risk in multiple large population studies. These results might be confounded by healthy user bias and a lack of specific information about meat sources. However, processed red meat is strongly implicated in driving chronic age-related disease and shorter lives in all studies. The same concern about saturated fats applies here, especially for men over 40 and post-menopausal women.

3. Healthy fats (unrefined cold-pressed oils, nuts, and fatty fish) belong at the top, next to legumes and vegetables. Olive oil, avocados, and macadamia nuts are rich in healthy Monounsaturated Fatty Acids (MUFAs) shown to reduce heart disease and all-cause mortality risk as part of Mediterranean-style dietary patterns demonstrated in large randomized controlled trials.

Fatty fish and walnuts are rich in Omega-3 fatty acids, which are essential for lowering cholesterol, providing systemic and vascular anti-inflammatory protection, and slowing down biological aging in interventional studies, along with vitamin D.

What it did well: shifted away from highly processed starches and added sugars toward protein and fat rich foods

Children are well positioned to benefit from the highly anabolic effects of milk and red meat proteins and are least affected by the risk of saturated fats, provided these are part of a relatively balanced diet.