Toni Petan

Group leader @JSI_SLO and Associate Professor @MPS_JS
#Lipids #LipidDroplets #CellBiology #Membranes #Ferroptosis #Metabolism

[Toni Petan @PetanLab]

Excited to share our new paper in @FEBSJournal! With @OndrejKuda & @FedorovaLab we show how LDs reshape the lipidome of PUFA-exposed cells & shift function within the same cell, revealing a context-dependent role in ferroptosis. Congrats Ana & @Lejaperne! https://t.co/sZlckc7fmt

[James Olzmann @OlzmannLab]

Save the date! 🔥 The 2027 FASEB Science Research Conference on Ferroptosis: From Mechanism to Medicine is coming to Denver, July 12–15!

We are excited to bring the ferroptosis community together again. Experts and newcomers welcome!

Please help spread the word! More info soon!

[Toni Petan @PetanLab]

Thank you, @KlaraJurecic and @programArs @rtvslo, for a very pleasant conversation about lipid droplets and their fascinating roles in our cells! https://t.co/oGllFx5jJk

[Toni Petan @PetanLab]

Hvala lepa @KlaraJurecic in @programArs @rtvslo za zelo prijeten pogovor o lipidnih kapljicah in njihovih nenavadnih vlogah v naših celicah!
https://t.co/bUVvDP8wVy

[Toni Petan @PetanLab]

@AjasjaLjubetic Congrats, Ajasja!! Well deserved🎉🥂

[James Olzmann @OlzmannLab]

New preprint! We find that fatty acid double-bond geometry alters their metabolic fate and ferroptosis sensitivity. Trans fatty acids are metabolized differently from their cis counterparts, reshaping membrane phospholipids and ferroptosis sensitivity.
https://t.co/XaaAGyDh6J

[Jeremy Baskin @basktastic]

Thrilled to share this #lipidtime story in @JCellBiol where, led by Shiying Huang and in collaboration with Tamas Balla’s lab, we uncover plasticity in phospholipid metabolism to preserve plasma membrane identity and integrity in the face of disease-relevant perturbations!

[Veijo Salo @VeijoS]

How does a cell remodel the ER membrane into a lipid droplet?

Excited to share our new preprint. We find that regulated opening of the seipin ring defines a functional ER–lipid droplet interface — and identify SMLR1 as a regulator of this transition.
https://t.co/eZEo2Oovmz

[Lauren Albrecht @TheAlbrecht_Lab]

Excited to highlight our newest work “Lysosome-derived methylarginine is a signaling metabolite of the lipidome” (1 / 6) @NataliesWish https://t.co/o3KqXo5qDb

[Cell Biology J-Club @cell_club]

Lysosome-derived methylated arginine is a signalling metabolite controlling the lipidome | Nature Cell Biology https://t.co/hhfHvf5t0F

[Nature Metabolism @NatMetabolism]

#Throwback

COMMENT | KS Lee, X Su & T Huan

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics

https://t.co/Cvu9LTGYrZ

[Maria Bohnert Lab @MariaBohnert]

A new review from the lab on #LipidDroplet heterogeneity in Current Opinion in Cell Biology. Big thanks to Philippe Chavrier and Chris Fromme for organizing an exciting #Membrane Trafficking special issue! https://t.co/6lS58kMBTL

[Eric Betzig @Eric_Betzig]

The danger of reasoning by analogy: "The behavior of things on a very tiny scale is simply different. (Atoms) do not behave just like particles. The do not behave just like waves. Atoms do not behave like weights hanging on a spring and oscillating. Nor do they behave like miniature representations of the solar system with little planets going around in orbit. Nor does it appear to be like a cloud or fog of some sort surrounding the nucleus. It behaves like nothing you've seen before."
Likewise, the cell is not a deterministic machine or factory. I think I can safely say that nobody understands the cell.

[nature @Nature]

Artificial intelligence is not replacing human intuition in maths and physics, but reimagining how questions are asked, explored and understood

https://t.co/hDA1iExhvb

[Journal of Cell Biology @JCellBiol]

Marjana Ndoci, @DeshwalSoni et al. show that #mitochondria prioritize survival over safety: when resources are low, they stop exporting Coenzyme Q to keep respiration running, at the cost of antioxidant protection. https://t.co/b8qdNgSmLZ

#CellMetabolism #Organelles

[Cell Metabolism @Cell_Metabolism]

DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function https://t.co/9chwzLCWT0

[Cell Biology J-Club @cell_club]

Membrane bridges and nanodomain partitioning govern membrane protein targeting to lipid droplets | Nature Cell Biology https://t.co/QFiIOLSpkc

[Henne_Lab @HenneLab]

Please re-post! Time is almost up to register for the 2026 FASEB Lipid Droplet Meeting. Abstracts are due May 31, 2026. See link below, and join us for an amazing SRC lipid meeting July 26-30! #LipidSRC

https://t.co/G6tAlhSxUF

[Ferroptosis and Oxidative Stress @Ferroptosis_SP]

📖FOS New Mini-Review!
“On the lethal mechanism of class III ferroptosis inducers” by Prof. Scott J. Dixon from @Stanford. Check to see why FIN56 causes ferroptosis but its analogs don’t.
🔗: https://t.co/CxKvo63fMK
#ferroptosis #Science #academic #cell

[Cell Metabolism @Cell_Metabolism]

Fasting opens a metabolic window that favors anti-tumor immunity https://t.co/2d0T4aSeGU

[James Olzmann @OlzmannLab]

Great to see this Spotlight article in Trends in Cell Biology highlighting our recent identification of a lipid droplet quality control pathway in which FSP1 protects PUFA-rich neutral lipids from peroxidation, thereby suppressing ferroptosis.
https://t.co/oumG9roaOh