Phil Strandwitz

Microbiome | Gut-Brain-Axis | Biotechnology | Co-founder and CEO @Holobiome_Inc

[Phil Strandwitz @PhilStrandwitz]

@owl_posting You make great content - would love to see the next post around the final paragraph re: China (and could chat about this with a few friends about this -- @DrSynbio)

[Jake Wintermute 🧬/acc @SynBio1]

I’m sure all the US pharma VCs who are off-shoring biotech R&D programs to China care only about patient well-being, as they say

But just in case they are also thinking about how this might play out for them financially, let me describe the current situation

Pharma is the most unpopular industry in the US

https://t.co/MgfAVKOGdD

US patients pay 70% of total worldwide profits for the pharma industry. Other countries are effectively free-riders

https://t.co/CcW3zjGiWa

Anti-China sentiment in the US is at an all-time high

https://t.co/j4YsKcxsUw

The current US administration is the most anti-China in history, believes the covid pandemic was engineered in a Chinese lab
https://t.co/Pc3Br2Kfn0

And in this political climate, with the US public being this deeply set against you, in an industry that only exists because US politicians allow you to take profits that no other country on earth tolerates, you have chosen the year of our lord 2026 to ramp up your off-shoring efforts to China

My Brothers in Christ, the US biotech industry and all of your portfolios are hanging by a thread. Do not dare the American people to hate you even more

[owl @owl_posting]

bleak that the primary people who are worried about chinese biotech are people who actually work in the field, and everyone telling them to chill out are either VC’s or journalists

[Select Committee on China @ChinaSelect]

WATCH | @RepLaHood questions biotech leaders on how China is cornering the medicine market and what it means for patients and national security.

"China’s rapid advancements in biotechnology are challenging America’s leadership. We must ensure life-saving innovation starts and stays here in the U.S., for the sake of patients and national security."

[Select Committee on China @ChinaSelect]

WATCH | @StrandTx's Dr. Jacob Becraft warns, "a future where we hand control to China over the discovery, development and manufacturing of the medicines we rely on is truly not far away.”

The race for clinical data is the race for global leadership.

[Phil Strandwitz @PhilStrandwitz]

@malikules

[Phil Strandwitz @PhilStrandwitz]

@kulesatony I have always thought that if we could reduce the friction of exposing society to it's problems and/or unknowns, give those curious the tool kit(s) to tinker, and a coordinated means to contribute, that same Minecraft/RPG grind energy could be funneled towards such innovation.

[Phil Strandwitz @PhilStrandwitz]

Love these "Visions of the Future" posters from the Jet Propulsion Laboratory of @NASA . I'm thinking we need something similar for what our microbial future will be.

https://t.co/5NtnWorieH

[Phil Strandwitz @PhilStrandwitz]

I'm ready for this! Can't wait to participate in my first SynBioBeta and share how we're using our microbiology-first platform to map the gut-brain-axis. If the pre-conference call (with around 150 attendees) is an indication of the energy of the event, it's going to be a blast!

[John Cumbers @johncumbers]

Our gut #microbes may hold the key to overcoming some of #medicine’s most pressing challenges. Learn about how scientists are translating the emerging science of the human #microbiome into the next generation of #probiotics, and how the gut-brain connection plays a pivotal role in mental and digestive health in this session at #SynBioBeta2024 (May 7, 1:45 pm - 2:30 pm) https://t.co/2ZG7J19wY0 #neurotech

[Phil Strandwitz @PhilStrandwitz]

@dunkhippo33

[Phil Strandwitz @PhilStrandwitz]

@JTRobinsonLab @motifneuro Awesome - well done Jacob!

[Phil Strandwitz @PhilStrandwitz]

@ugizashinje @bryan_johnson I lead a biotech that does a lot of translational microbiome research. One of our projects includes isolating and growing communities of microbes from people + mapping what foods/ingredients they interact with. Currently can't this level of resolution with sequencing data alone.

[Phil Strandwitz @PhilStrandwitz]

@titanioustom And it's probably not just equity in many of these cases - in the Oxford Nanoimaging deal it was 50% equity (!) and 3.5-6% of net sales on a sliding scale.

[Phil Strandwitz @PhilStrandwitz]

Super excited to see this published --> a pilot placebo-controlled FMT trial for depression, the first of its kind. What a beast of a study to get done during a pandemic. Sets us up well for a powered trial (first link = protocol; results = linked at the end of the thread).

[Dr Jessica Green @Jessica52870672]

I'm excited to share the results of our RCT of faecal transplants for depression! The first published controlled human evidence supporting the acceptability, feasibility and safety of faecal transplants for the treatment of a mental health disorder https://t.co/WPUng9kKVY

[Phil Strandwitz @PhilStrandwitz]

@jmigueljd @J_LHeureux23 @BCMSpaceHealth @DARPA @DoritPhD Way to go Miguel! Super cool

[Phil Strandwitz @PhilStrandwitz]

@gilbertjacka "Probably perfection"

[Phil Strandwitz @PhilStrandwitz]

When passions for poop science and writing intersect - a great read from @StephenSkolnick, one of my favorite Holobionts.

[Stephen Skolnick @StephenSkolnick]

I started a substack! Please subscribe for deep dives on the neurochemistry of mood and its connections to the gut, advice on caring for your microbiome, and the occasional pontification on other aspects of health, diet, and science philosophy.
https://t.co/8hpDqhBkIg

[Phil Strandwitz @PhilStrandwitz]

The microbiome field has been watching -- great to see a positive vote for both safety + efficacy from the FDA's AdCom meeting for RBX2660 (Rebyota). Big congrats to @Rebiotix. A significant milestone + just the start of the incredible potential in manipulating our microbes

[Phil Strandwitz @PhilStrandwitz]

@titanioustom @MichaelRetchin @JocelynnPearl Gets me every time.