Brown-Séquard syndrome is a classic bedside pattern:
one-sided weakness with opposite-side pain and temperature loss — recognize the tract anatomy, localize the lesion.
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Goodpasture syndrome is a classic USMLE-tested condition characterized by the triad of hematuria, hemoptysis, and rapidly progressive renal failure in a young man, typically in his 20s to 40s. It results from a type II hypersensitivity reaction in which anti-glomerular basement membrane (anti-GBM) antibodies are directed against the α3 chain of type IV collagen, a key structural component of both the alveolar and glomerular basement membranes.