Takis Prinos

Cancer researcher looking for novel drug targets, promote collaboration and open science

[Nick Robinson @bbcnickrobinson]

Wow

[Takis Prinos @PrinosTakis]

@MariosGeorgakis You raise good points. I was considering trying betaine supplements without reading the whole paper! Now you seeded doubts. I'll read it through and make my own conclusions.

[Takis Prinos @PrinosTakis]

@NTFabiano It is well known that steroid hormones regulate the brain so this is a no brainer. I just heay about the post-finasteride syndrome in a subset of men that take it. Can't believe the negative stance of some physicians towards men that suffer from it. Can you do a thread about it?

[Takis Prinos @PrinosTakis]

@BrandonLuuMD Is it soluble in water? I noticed it stays as a slurry. Do you need to heat it up to dissolve completely or it doesn't matter?

[Takis Prinos @PrinosTakis]

@EricTopol @NatureMedicine @AdamRodmanMD @jonc101x Time to modernize our old and outdated health care system.

[Takis Prinos @PrinosTakis]

@LidskyPeter If we can rejuvenate individual cells e.g. by reprogramming them, then I don't see why it is not feasible at the organismal level. It's a matter of getting rid of senescent cells and replacing them with new ones.

[Takis Prinos @PrinosTakis]

@davidasinclair @CellPressNews Very interesting results! An increasing number of recent studies show that the cancer fighting phenotypes observed using epigenetics inhibitors are due to viral mimicry i.e. retroviral element activation that result in IFN signalling, immune system activation and cell death.

[Takis Prinos @PrinosTakis]

@MitoPsychoBio I think GDF15 has been associated with aging in mice. There was a controversial study claiming they could reverse aging if they blocked GDF15 with antibodies!

[Takis Prinos @PrinosTakis]

Every lab has had experience with bad antibodies. They are a big waste of time, money and lab resources and lead to false and irreproducible results. Initiatives such as the SGCs YCharOS help pinpoint the good ones and will save time, money and resources.

[nature @Nature]

Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this https://t.co/xpo9iAmV0m

[Takis Prinos @PrinosTakis]

@ggmacleo @angerslab @MolaeiFatemeh Congrats Graham, Fatemeh and team!

[mcguiganlab @mcguiganlab]

🔥NEW PAPER ALERT🔥: our study on perturbing CAF activation to modulate tumor invasion is out in @Biomaterials. If you like bioengineering, targeted screening and cell phenotype perturbations, this story is for you! 👀 (https://t.co/Jv8cXvPhXc

[Takis Prinos @PrinosTakis]

@BoWang87 Congrats Bo, very cool tool! Question for you: can it predict the functions of new isoforms? Also does it analyze alternative polyadenylation isoforms ?

[Takis Prinos @PrinosTakis]

@aledmedwards Now they are asking for 2 pages of EDI statements for new faculty or scientist positions!

[nature @Nature]

World-first therapy using donor cells sends autoimmune diseases into remission https://t.co/YdzCzEogXq

[Takis Prinos @PrinosTakis]

@AIneurolab I think clinical trials of GLP1 drugs are looking into aging and neurodegeneration. RNA metabolism also seems to be important in NSC aging.

[Takis Prinos @PrinosTakis]

https://t.co/AusvsiZvuX

[Joe Walton @Cool_Genes]

🚨 Excited to share our new publication in @NatureComms on PRMT inhibition in kidney cancer! 🙌 Big thanks to @laillesuhnrese1, @thesgconline, @CherylArrowsmi1, @BrianRaught, and the entire team!👏Read more here: https://t.co/MBvnoo5CKM #cancerresearch #kidneycancer #UHN

[Yue Lab at Newcastle @TheYueLab]

Great public engagement initiative

https://t.co/mx5VK31ooa

[Takis Prinos @PrinosTakis]

@AIneurolab Congrats Angelo and team! Amazing work!

[Cheryl Arrowsmith @CherylArrowsmi1]

Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles https://t.co/S4w50anoA7
Awesome study by Manisha Yadav, @LabScribbles , @pouladi , @hansenhe7 and Pearson Labs