Eva Rose Balog

associate professor of chemistry @unetweets. protein biochemistry, biophysics, biomaterials. mom of three.

[Jake Wintermute 🧬/acc @SynBio1]

Researchers - have you considered using engineered protein binders as an alternative to tradtional antibodies for Western blots, fluorescence microscopy, etc?

Interested in the practical barriers to general adoption of AI-engineered binders for research

[Paul Robustelli @PaulRobustelli]

Proud to share a new manuscript:

"Ensemble docking for intrinsically disordered proteins"

from @DartmouthChem undergrad Anjali Dhar 24' and grad student Tommy Sisk. We present ensemble docking strategies for IDPs that, remarkably, seem to work!

(Links in thread below)

[Homeworld Collective @HomeworldBio]

The Garden Grants application window is open!

We're offering $50k-$150k grants (up to $1M total) to support de-risking ideas that intersect biology and GHGR.

Application window closes 2/28.

Apply here: https://t.co/GSote6M1E9

[Erik A. Rodriguez @erin_rod_phd]

Today, I would like to honor the memory of Roger Y. Tsien, born on February 1, 1952. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more!

https://t.co/YdWfBPUOBB

#FluorescenceFriday

[nature @Nature]

Obituary: Martin Karplus (1930-2024) theoretical chemist who first simulated proteins using molecular dynamics

https://t.co/taGGs0aBew

[J. Am. Chem. Soc. @J_A_C_S]

Modulation of Protein–Protein Interactions with Molecular Glues in a Synthetic Condensate Platform | Journal of the American Chemical Society
@TUeindhoven https://t.co/24Q1pc3fId

[Dr. J. M. Groh @JMGrohNeuro]

If you had a study section or similar NIH travel canceled, or indeed if you have not, can you reply with the dates of the meeting and whether it's on or not? Would be good to get a sense of what time period this applies to for now (esp if NIH is muzzled and can't announce it...)

[Jake Wintermute 🧬/acc @SynBio1]

Every synthetic biologist, every biochemist, when they dream, will sometimes hear a voice calling

A whisper on the wind, as impossible as infinity, as sweet as the ambrosia of the very Gods

"Engineer RuBisCo"

And this paper takes us one step closer
https://t.co/xS0ns6UGlY

[Eva Rose Balog @ProfBalog]

I've never seen anything quite like this, very cool

[J. Am. Chem. Soc. @J_A_C_S]

Observation of the Protein-Inorganic Interface of Ferritin by Cryo-Electron Microscopy | Journal of the American Chemical Society @ASU @ASUBiodesign @ASUResearch https://t.co/3zV1kDU808

[nature @Nature]

Those recovering from drug or alcohol misuse speak up — and say they wish more researchers could do so freely at work

https://t.co/WtxHec3F6P

[David S. Goodsell 🏳️‍🌈 @dsgoodsell]

I'm very happy to announce that I have retired! I'm equally happy that @janetiwasa has agreed to continue the Molecule of the Month @buildmodels. Read about this at https://t.co/fs5LBpfL9E

[Katie Galloway @GallowayLabMIT]

Failure to establish a reasonable digital folder hierarchy

[Michael Fischbach @mfgrp]

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

[Institute for Protein Innovation @ipiproteins]

Check out this @SpecificaInc AI challenge (co-authored by André Teixeira, now at IPI) on #antibody affinity maturation, #affinity rank prediction for Ab discovery, and computational antibody design! @NatureBiotechl #proteinscience https://t.co/oH1sWFNRP7

[Merriam-Webster @MerriamWebster]

Tag yourselves.

[Michael C. Jewett @MichaelCJewett]

Can protein expression be "solved"? And how can we enable predictive design?

Check out this project led by @erika_alden_d @Align_Bio

https://t.co/SjFqMMCULZ

[Eva Rose Balog @ProfBalog]

absolutely thrilling protein design - for its findings, applications, and most of all future questions. This is how you play all day.

[Adam Broerman @adam_broerman]

Excited to announce our new #proteindesign strategy for allosterically controlling the kinetics of protein-protein interactions! Read on for cool applications in cytokine signaling, biosensing, and protein circuits. https://t.co/jBIHq10Ykd

[Eva Rose Balog @ProfBalog]

from the link: Photographs by Price Sewell.

[Eva Rose Balog @ProfBalog]

interesting metabolic biochemistry *and* pictures of bats on a treadmill

[Alexander Schubert @alexschbrt]

Vampire bats literally run on blood.

Their body can oxidize non-essential amino acids from blood meals to rapidly create ATP, fueling their muscles.

https://t.co/PTdOCWBsEj

[nature @Nature]

Tools such as Rosetta and AlphaFold have redefined the protein-engineering landscape. But some problems remain out of reach — for now https://t.co/i6nS7QVh8P