Rasmus Krogh Norrild

Postdoc with @alexander_dtu at @DTUbioengineer and former student at #LinderstrømLang Center for Protein Science, UCPH @uni_copenhagen

[Rasmus Krogh Norrild @RasmusNorrild]

We are finally ready to share the preprint version about our use of mRNA-display to study what makes disordered proteins form condensates, at the proteome-scale!

Check it out here:

[bioRxiv Biophysics @biorxiv_biophys]

Proteome-scale quantification of the interactions driving condensate formation of intrinsically disordered proteins https://t.co/yxsB8X9aAg #biorxiv_biophys

[Joseph Rogers @JosephRogers100]

mRNA display continues to astound. Fantastic collaboration with @alexander_buell, led by the peerless @RasmusNorrild. ~100,000 peptides and their propensity to join the phase separation of a model disordered protein. https://t.co/hpgcDm8YC4

[Kresten Lindorff-Larsen @LindorffLarsen]

Check out @RasmusNorrild's work with Alex Buell @biophysics_dtu and @JosephRogers100 developing and using Condensate Partitioning by mRNA-Display to probe phase separation of ~100.000 sequences, and @SoBuelow simulations to support and analyse the experiments

[Rasmus Krogh Norrild @RasmusNorrild]

Great timing! Our TDIPS method to study biomolecular condensates highly efficiently is now published in Angewandte Chemie, while I am attending an amazing conference @EMBLEvents #EESPhaseSeparation. Check out the paper here: https://t.co/ONIWGCNVH3

[Soumik Ray @SoumikRay5]

In this comprehensive review now published in @JChemPhys , Alex (@biophysics_dtu) and I highlight the recent advances in the experimental methods to quantitatively study biomolecular phase separation. Really happy to finally see it online!
https://t.co/tuRpUIKx6y

[Frederik Theisen @FrederikTheisen]

Publication 🧵: Excited and proud to share that our work using deep network hallucination to scaffold an enzyme active site has been published (@ACSSynBio #EditorsChoice)! Dive in with us! 👇https://t.co/yK727Nr016

[Rasmus Krogh Norrild @RasmusNorrild]

@titus_franzmann Congratulations! Very cool stuff.

[Joseph Rogers @JosephRogers100]

Was a delight to witness the development of these amazing helix-binding proteins. Congratulations to
@SusanaVazTor @PreethamVi @proleu @_JosephWatson and all on the team from the David Baker lab.
https://t.co/fymEvqox7s

[Rasmus Krogh Norrild @RasmusNorrild]

Finishing a PhD is a tough job, but also an amazing journey of growth and learning. It was therefore amazing to conclude the thesis by being able to discuss my work with @KnowlesLabCamb, @BenLehner, and @rbdamgaard!
Thanks to all involved - especially my supervisors!!

[Antonín @KunkaAntonin]

It's finally out ;) I'm happy to share the results of our work on comparing different protein stabilization strategies which resulted in three highly thermostable haloalkane dehalogenases with improved catalytic efficiencies. @LoschmidtL
https://t.co/Q3ZU8muIkq

[Rasmus Krogh Norrild @RasmusNorrild]

Check out TDIPS, which can induce protein phase separation in a laminar flow! This is an easily accessible assay that probes most parameters of a protein's phase behavior, e.g. for biomolecular condensate formation. Read more in the thread below or in the pre-print.

[Soumik Ray @SoumikRay5]

If you are working or planning to work on alpha synuclein phase separation, then you will find my new article insightful. @alpha_synuclein
@NatureChemistry
@DTUbioengineer

Also go through our research journey here: https://t.co/QrffT2aPvV

[Joseph Rogers @JosephRogers100]

Join us! PhD position open! @HenrietteAutzen and I are offering one-hell-of-a- project: using high-end membrane protein science to enable the screening of ultra-large libraries of cyclic peptides. Funded by @DFF_raad, in collaboration with @LabPless. https://t.co/ZE3W2cYVvX

[Rasmus Krogh Norrild @RasmusNorrild]

@alexander_buell @Bennibolo Yes - really cool paper and amazing data!

[Joseph Rogers @JosephRogers100]

Alpha-helical peptides captured by designed proteins. Biomedical applications abound. Special thanks from us to @_JosephWatson --- new binders from peptide sequence alone. Congrats to the big team @SusanaVazTor @proleu @fabian_hink @DaveJuergens
https://t.co/eYSMiqLoDC

[Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍 @Jpmorth]

Great collaboration between the Copenhagen University friends Jakob Winter Larsen , @LindorffLarsen Kristoffer Enøe Johansson and Charlotte O'Shea. With a cool methodological approach to stabilize proteins. Supported by structural work performed at @DTUbioengineer, #research.

[Rasmus Krogh Norrild @RasmusNorrild]

Now it is possible to read the final version in @CellRepMethods!
https://t.co/a53yQYh67a

[Rasmus Krogh Norrild @RasmusNorrild]

I am happy to share our story from my Master's with @kristofferenoee. We devised a cheap and accessible route to protein stabilization by modelling high-throughput screening data, which increased stability of a model protein by almost 50% in a single step. https://t.co/qMByeZHYfp

[Michael Bang Petersen @M_B_Petersen]

I dag blev sidste Detektor-program sendt. Til nytår skæres Orientering & Deadline.

Skader det den demokratiske samtale?

"Nej", tænker du, "de programmer er for en snæver kreds, som kan få andre nyheder. Demokrati handler om bredden."

Men forskningen siger noget andet.

🧵 1/9

[Rasmus Krogh Norrild @RasmusNorrild]

Amazing to get feedback on our preprint from the review crowd at @ASAPbio_!

[ASAPbio @ASAPbio_]

@L_L_Dougherty @dutta_soumita @PracheeAC Our biochemistry preprint review crowd reviewed this preprint by @RasmusNorrild & colleagues, you can see the public comments here: https://t.co/u14lAc0eyQ

More reviews to come in the coming weeks!

[Rasmus Krogh Norrild @RasmusNorrild]

@ASAPbio_ @L_L_Dougherty @dutta_soumita @PracheeAC Awesome initiative - we are very grateful for your comments and will use the feedback in our revised paper!