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Really excited to share this work led by Jinglong Wang. It's an in-depth look at end joining that reveals additional insights into repair hierarchy and V(D)J recombination. Many thanks to the thoughtful reviewers, @ScienceAdvances, @AmericanCancer, and @TheVFoundation.
Eliminating core NHEJ factors reveals two distinct alternative end joining mechanisms. We investigate how one of them collaborates with the DDR to suppress MMEJ. https://t.co/G9cX4GYtNA
#UCIMedSchool researchers from the @PannunzioLab have identified a key enzyme contributing to #cancer health disparities within the Latin American population. https://t.co/6NdNoTAL1F #UCIrvine
Thrilled to share the first manuscript from Verma Lab! We uncover that cleavage of abasic sites represents a new approach to enhance PARP inhibitor sensitivity. Thankful to the perseverance and hard work of my students @natasha_m_r and @LindseyA2000
https://t.co/wX2AQvAgiV
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) https://t.co/XFutf8w6ni. Thread ⬇️⬇️⬇️ (1/8)
Excited to share Jinglong's publication on DNA-PKcs role in suppressing translocations! Pro tip in the manuscript to enhance gene editing. https://t.co/jaI0KLRXmx
Breaking News! Partial DNA-PKcs inhibition promotes translocations via NHEJ while complete inhibition promotes the transition to using more MMEJ. See Jinglong Wang's study from the FrockLab below: https://t.co/TdCLcaBgQj
Ringing in the New Year with a preprint Led by Jinglong Wang from the FrockLab: DNA-PKcs Suppresses Illegitimate Chromosome Rearrangements
https://t.co/FcJpj5xk7K
We are searching for an expert in DNA repair and DNA damage responses to join our team as an Assistant or Associate Professor and develop a robust research program in this area. Learn more and apply: https://t.co/wxpZnrg3IN #cancerresearch#clinicaltrials
Checkout our FLASH-RT paper on chromosome translocations free for the next month! Thanks to @elsevier for helping to share the knowledge! #FLASH https://t.co/F4g49FkWoe
Excellent work by our team and collaborators demonstrating similar translocation patterns between FLASH and Conventional RT! @VozeninC@BLoo_LT_SABR@LimoliCharles#FLASH https://t.co/3uLmlSDUiw
New paper by R Frock and team showing DDR after FLASH and conventional dose rate is similar. Great collaboration
Thanks Rich #flash@BLoo_LT_SABR@RichardFrock@LimoliCharles https://t.co/1WBRJ41kny
We're officially moving to open-beta! Join now at https://t.co/O1Qnl6hMgn. **Please read our directions carefully** or check out our detailed how-to guides here: https://t.co/R0ZpVsyz8a. Most importantly, have fun!