Robin H. van der Weide

Postdoc Integrative Single-Cell Functional Genomics in the @kind_jop lab (@_Hubrecht). PhD from @NKI_nl

[Robin H. van der Weide @RobinWeide]

Happy to see the improved and expanded version of this out in @naturemethods 🎉

https://t.co/T4zrBnGXmI

[Robin H. van der Weide @RobinWeide]

📯 Thread alert: introducing MAbID, a new combinatorial single-cell profiling method. This was a team effort between PhD-candidate Silke Lochs and me, with the full support of the @kind_jop lab at @_Hubrecht.

Read all about it: https://t.co/6p5RgmqaqX

[Niko McCarty. @NikoMcCarty]

.@nehaludyavar is doing interesting work.

He's currently reading Uri Alon's book to learn Systems Biology. As he learns about new concepts, he writes about them and makes super clean graphics + interactives to accompany the text.

He's "learning in public" in a beautiful way.

[Stefano Giustino Manzo @stefanogmanzo]

So thrilled to see our work on regulation of transcriptional repression in lamina-associated published in @embojournal. Thanks to all the authors!! Thanks to all the authors for their fantastic contribution. https://t.co/7DLzVQzVgZ

[Robin H. van der Weide @RobinWeide]

@stefanogmanzo @embojournal Congrats Stefano!!

[Rob Klose @RobKlose]

Great to see @AleksSzczurek's paper out today! A wonderful team effort with @emmy_dimitrova , @Jess_R_Kelley , and @blackledge_neil. Have a look if you are interested in how #Polycomb controls transcription to repress gene expression.
https://t.co/MJPJ8E8N0r

[Robin H. van der Weide @RobinWeide]

@golobor Congrats Anton, exciting times ahead!

[dana_peer @dana_peer]

4) The scientific method also applies to computational results: proper controls and negating all alternative hypotheses are just as important in computational biology as in bench experiments.

[Campàs Lab @CampasLab]

Out today in @NatureMaterials, the updated version of our work on nuclear jamming in organogenesis 👁️🧠 Thanks to the reviewers (yes, thanks 😊), we have added a lot of new data. Check below for the new results... 🧵

➡️https://t.co/iLAdn8x2q2

[Evgeny Kvon @evgenykvon]

How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: https://t.co/n0p7BdxSdq 1/

[Fabian Theis @fabian_theis]

In need of an educational weekend read? Check out our new perspective @CellCellPress with Rahul @satijalab. Led by @mo_lotfollahi & @YUHANHAO2, we outline how to automate single-cell data analysis via reference mapping. https://t.co/vHvBvOKuB1

[Lior Pachter @lpachter]

The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In https://t.co/rVOiR847CY w/ @Josephmrich et al. we take a close look. The results are 👀 1/🧵

[Pall Melsted @pmelsted]

In this preprint https://t.co/IYUCt8DScv with @sindri_e we compared seven widely used methods for batch correction of single cell RNA-seq data. We found that all but one of the methods introduce batch effects when there are none. 1/N

[Anders Sejr Hansen @Anders_S_Hansen]

(1/14) Excited to share our new work on ZNF143/ZFP143 by @DomenicNarducci

ZNF143 has been widely reported to be a general loop factor

Instead we and @deWitLab in a companion preprint show that ZNF143 is a TF with no loop function:
https://t.co/kqvujLFjEN
https://t.co/UJD9mNKcWq

[Robin H. van der Weide @RobinWeide]

@deWitLab @hansen_lab Congrats to all, great (th)read. What a rollercoaster!

[deWitLab @deWitLab]

You may know ZNF143 as a looping factor. We show together with the @hansen_lab that this is not the case! If you want to know why and what it does instead do read our thread below:
https://t.co/2oPbiy0SoW

[Hubrecht Institute @_Hubrecht]

Congratulations to Puck Knipscheer and @kind_jop, who have been awarded @NWOFunding Vici grants for their research on resolving dangerous DNA structures and the role of chromosome organization in determining cell identity respectively.

[deWitLab @deWitLab]

We have an open post-doc position in the lab. If you're interested in studying the role of the cohesin complex in gene regulation, don't hesitate to apply. Come and join us in beautiful Amsterdam! Email me if you have specific questions. https://t.co/j7vo2xq5RR

[Latif Nasser @latifnasser]

Last January, I noticed something peculiar in my 2yo’s bedroom that - after a year of obsessive reporting - led me to a profound cosmic revelation about what’s even possible in our universe. A 🧵.

[Moritz Bauer @MoritzBauer_87]

📢We are very excited to announce the second edition of the Dutch Embryo Model Meeting #DEMM24

Are you working with embryo models such as 2D/3D #gastruloids or #blastoids?

Join our meeting and submit an abstract!

https://t.co/ssMaC6ts35
@oncodeinstitute

[Bas van Steensel lab @bvansteensellab]

New preprint from our lab: LAD scrambling to figure out how they interact with the nuclear lamina. https://t.co/yxJNptqS0I

[Igor Ulitsky @IgorUlitsky]

Next week is the 42nd time my lab will run the journal club (JC) in a lab meeting in the 'collaborative' format, which we do 1/month, and I think it is the ultimate journal-club format, so a 🧵 about it