Hubrecht Institute

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[Hubrecht Institute @_Hubrecht]

What if science truly is like volleyball, where teamwork and support are everything? We spoke with Francesca Mattiroli, who recently earned tenure, to explore this question and more. Read her inspiring story here 👉 https://t.co/g5R3ZpcCNF

[Hubrecht Institute @_Hubrecht]

On Jan 9, dr. Henriette van Beijnum defended her PhD on the regenerative abilities of the spiny mouse. Congratulations! Her findings, like the flexible “basket-weave” scar pattern, could help improve treatments for heart attacks and chronic wounds. See https://t.co/Ecd9WmJRMw

[Hubrecht Institute @_Hubrecht]

Researchers from @BakkersLab have successfully repaired damaged mouse hearts using a protein from zebrafish. This study marks a promising step toward regenerative therapies to prevent heart failure. Read more https://t.co/9JFR2fXjYu

@DEMdeBakker
@BouwmanMara
@J_Bakkers

[Hubrecht Institute @_Hubrecht]

Researchers from the @TheCleversLab developed a method to grow organoids using a bacterial protein: Invasin. The study, published today in @PNASNews, shows that Invasin offers a sustainable, affordable and animal-free alternative to current methods. https://t.co/16auPZDk8J

[Hubrecht Institute @_Hubrecht]

How reliably is the epigenome passed from one cell to its daughter cells? @AlexandervanOu1, @jervdberg, @groth_anja & @Lleonie received a @novonordiskfond grant to answer this question, which will lead to new strategies to prevent disease and combat aging https://t.co/tnRCQCsbny

[Hubrecht Institute @_Hubrecht]

@kind_jop has been awarded a grant from @kwf_nl to develop a highly sensitive method for detecting cancer using epigenetic signatures in blood plasma. This innovative approach has the potential to revolutionize early cancer diagnosis and monitoring. See https://t.co/XmYPYn6yHT

[Hubrecht Institute @_Hubrecht]

The inaugural Hubrecht Symposium is on March 13th, 2025! Join an inspiring day on molecular & developmental biology. This annual event highlights the role of fundamental research in Dutch science. Free of charge! Submit your abstract by February 13th. See https://t.co/sKGYMwpiZo

[Hubrecht Institute @_Hubrecht]

Congratulations to dr. Yasmine El Azhar, who successfully defended her thesis: Notch signalling dynamics during mouse development and homeostasis. She developed a mouse model to visualize real-time Hes1 oscillations in single cells @SonnenKatharina group. https://t.co/AvOnTdWbfc

[Hans Clevers @HansClevers]

Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. https://t.co/mk4MdczkTM 1/

[The Clevers Lab @TheCleversLab]

📢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in @CellCellPress by @AmandaARolf , @HansClevers and collaborators. See the article here: https://t.co/xcuc8drybh

[Hubrecht Institute @_Hubrecht]

Researchers from @TheCleversLab created an organoid that mimics the human fetal pancreas. Unlike previous models, this organoid has all three key cell types. They also identified the stem cell that develops into these cells. Curious? https://t.co/Sm13BsXjWC

@AmandaARolf @Roche

[Hubrecht Institute @_Hubrecht]

🧬New research published @NatureComms reveals how cells fix damaged DNA. Researchers from the @kind_jop group mapped repair proteins and show how they form 'hubs,' to coordinate repairs, almost like a 'repair café'. Learn more: https://t.co/3Ps1Qri1Ag #DNARepair #SingleCell

[Hubrecht Institute @_Hubrecht]

Researchers from the Mattiroli group discovered that DNA packaging in cells can directly impact the speed of DNA copying during cell division. The packaging sends signals through an unusual pathway, affecting the cell’s ability to divide and grow. More: https://t.co/Fgv1RynmHK

[Hubrecht Institute @_Hubrecht]

Our position for tenure-track principal investigator is still open! As junior group leader you will develop your research line within our lively scientific community. Ready to establish your own research group at the Hubrecht Institute? Apply before 15-11! https://t.co/hXb5jz4Bee

[Hubrecht Institute @_Hubrecht]

Researchers from the Organoid group have developed a new organoid model to study the origin of colorectal cancer. The researchers studied the sequential accumulation of mutations contributing to tumor formation. @HansClevers @Tom_Mizutani Read more here: https://t.co/0pLamFGI9p

[Hubrecht Institute @_Hubrecht]

Read more here: https://t.co/43SEsJKRs3

[Hubrecht Institute @_Hubrecht]

Francesca Mattiroli, group leader, receives a Vidi grant from the Dutch Research Council (NWO). With this funding, she and her team will investigate how DNA and its packaging are copied during cell division. Their findings could in the future help in fighting diseases and aging.

[Hubrecht Institute @_Hubrecht]

Congratulations to all researchers on this great new paper in @ScienceMagazine, including @BeumerJoep @geurts_maarten @VeerleGeurts @NinoukAkkerman @DanielKruegerDK @JensPuschhof, in collaboration with @Roche @IHB_Research @MaastrichtU @UMCUtrecht

[Hans Clevers @HansClevers]

New @ScienceMagazine study in collab with @IHB_Research!
We identified novel receptors on enteroendocrine cells (EECs) that regulate secretion of endogenous hormones. These harbor therapeutic potential for metabolic disease. Read the paper https://t.co/yycQFE72QY  or 🧵⬇️

[Hubrecht Institute @_Hubrecht]

A team from the Organoid group and @IHB_Research @Roche has uncovered nutrient sensors on gut hormone-producing cells using organoids. The characterization of these sensors will help in treating metabolic & gut motility disorders. @BeumerJoep @HansClevers https://t.co/8SWEOPoMZw