Ryan Muir

Postdoc in the Bogyo Lab at Stanford. Ph.D. from UCSF in the Renslo Lab. Chemistry and Chemical Biology

[Ryan Muir @RyanKMuir]

Excited to share our recent publication on identifying & targeting ferrous iron addiction in KRAS-driven cancers using the TRX-based prodrug strategy.
https://t.co/Qc0vHpL4SH

[Ryan Muir @RyanKMuir]

It was a pleasure working with @__mguerra__ on this review. I love this topic and am excited to see where the field is moving!

[Matthew Bogyo @mbogyo]

Our latest review on activity-based diagnostics is out at ACS Chem Bio! Check it out using this link which will allow you to download for free. Great work from @RyanKMuir and @__mguerra__

https://t.co/78aCqyFJyH

[José Montaño @Chemystified]

Thrilled to share that the Zaro Lab's first ever preprint is now LIVE on @ChemRxiv 🧪 We developed a new, highly-selective (like, *really* selective) covalent inhibitor of BTK through the simple elaboration of fumarate ester-based warheads (1/n): https://t.co/HZyQICJ8qk

[Michael Evans @mikeevans_ucsf]

Thanks to @LewisLabMSKCC for highlighting our work presented at @WMISWMIC developing nuclear imaging methods to better exploit the labile iron pool for cancer therapy @adamrenslo @UCSFimaging @RyanKMuir @nzhao2ucsf

[Ryan Muir @RyanKMuir]

@adamrenslo @mikeevans_ucsf Thanks Adam! It's crazy to see how far a quals project idea can go (especially when you have awesome collaborators!)

[SNMMI @SNM_MI]

A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients, according to research published in @JournalofNucMed. https://t.co/u26ySTlkjV

#PrecisionMedicine #Theranostics #Cancer

[Science Magazine @ScienceMagazine]

As repurposing drugs for #COVID19 has drawn much attention, a new study shows that drugs w/ antiviral effect through phospholipidosis are unlikely to be effective in vivo. Screening out such drugs may allow a focus on drugs with better clinical potential. https://t.co/4b4lh8xroD

[Adam Renslo @adamrenslo]

To photo-affinity, and enzyme/AA-reactive ABPs, you can add ABPs activated by intracellular labile iron. Congrats to Ying-Chu, Juan and collaborators @aPOPEtosis and @SJD956! #ferroptosis @J_A_C_S
https://t.co/Ci3OEYmE98

[Angewandte Chemie @angew_chem]

We are deeply sorry for the opinions expressed in the recent piece published in our journal.

We recognize the responsibility we have to our community and are conducting an internal investigation into this incident.

Read our full statement here: https://t.co/KMVqLpqm0A

[L.-C. Campeau Ph.D. @DrLCsquare]

I am very disturbed and disappointed by Prof. Hudlickly's comments in this article in @angew_chem where he makes the case that “diversity of the workforce” has a ”negative impact” on the field of organic synthesis (see the ridiculous figure!) https://t.co/409o4tW5e6

[Ryan Muir @RyanKMuir]

Figure 1 says that "diversity in the workforce" is having a negative impact on the field of Organic Synthesis. Additionally complains that grad students are no longer willing to "submit to their mentors." I can't believe @angew_chem published this.
https://t.co/PLNghQ7LFh

[bioRxiv @biorxivpreprint]

Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC) https://t.co/3cUKFJpcCx #bioRxiv

[Nature Portfolio @NaturePortfolio]

The findings of a Nature paper suggest that there may be potential for developing treatments for #COVID19 by repurposing drugs that are already approved or under investigation for other conditions. https://t.co/TqILFgyLuN

[Kevan Shokat @kevansf]

Our collaboration with @QBI_UCSF on #SARS_COV_2 host factors and how to drug them is online now https://t.co/btrWHwApYt thanks to everyone. #COVIDー19 @UCSF @UCBerkeley @HHMINEWS

[Mona Chalabi @MonaChalabi]

If you speak a language other than English and want to help me translate this, there's a form here https://t.co/lNDzRy9RbH thank you thank you thank you

[Adam Renslo @adamrenslo]

Sneaking antibiotics into bacteria with siderophore-iron(III) conjugates is a cool trick. In our latest paper in @ACS_Infectious we instead uncage antibiotics via reaction with free iron(II) at infection sites https://t.co/FvkwlmWa7A @EricSkaar @RyanKMuir @erin_r_green

[Ryan Muir @RyanKMuir]

@crystalmet @adamrenslo @ACS_Infectious @EricSkaar @erin_r_green We can! Check out our lab's papers on this strategy here:
https://t.co/dRy9yv1yxV
https://t.co/wNZUddhBY6

[Ryan Muir @RyanKMuir]

@NHL A lot of upset fans, especially when we're told it didn't show up because the people handling the Cup were too busy partying

[Ryan Muir @RyanKMuir]

@NHL Bad look saying you'll show the Stanley Cup at the Giants game from the 5th inning on and no-showing, leaving hundreds of fans waiting...

[Ryan Muir @RyanKMuir]

@Ella_Maru @ACSCentSci @adamrenslo @mikeevans_ucsf @UCSF @UCSFimaging @ucsfpharmacy We're working towards that right now! Stay tuned!