Ryan Smith (@rssmith.bsky.social)

Research Associate Professor at the Laureate Institute for Brain Research focused on computational neuroscience, interoception, emotion, and decision-making

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Huge congrats to Claire Lavalley on this new paper. https://t.co/1HZibdOXbQ Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Congrats to Navid on his new paper in Molecular Psychiatry! Computational modeling showed learning rates and uncertainty sensitivity could distinguish affective disorders from substance use disorders, while forgetting rate was affected transdiagnostically https://t.co/zcog0mSmUi

[Mark Solms @Mark_Solms]

A nice podcast 'debate' with a colleague who has slightly different views about consciousness than me. (I had to leave 15 minutes before the end -- they ran over the allotted time -- in case you wonder why I suddenly disappear from the conversation!
https://t.co/GiRBd7AD9n

[Communications Psychology @CommsPsychol]

Computational modeling revealed that individuals with methamphetamine use disorder show reduced information-seeking and slower belief updating when trying to maximize long-term reward.
@CarterMGoldman @toru1789taka @RyanSmith_LIBR
https://t.co/FfD7gUQxN7

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Big thanks to co-authors as well! @NRDlab @SamuelTaylorCS @KhalsaLab @mpwpaulus (and others without Twitter)

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Congratulations to @toru1789taka and @CarterMGoldman on their newly published paper!

This paper shows that individuals with methamphetamine use disorder show reduced directed exploration and slower dynamic learning rates in both high/low anxiety states

https://t.co/gUFBPx6KAg

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

These and other results in the paper could help explain difficulties considering abstinence and vulnerability to relapse. Big thanks to
@docqhuys @mpwpaulus @KhalsaLab @MarishkaMehta @SamuelTaylorCS and other twitterless co-authors for their very helpful contributions!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Huge congrats to Claire Lavalley on this new paper. https://t.co/1HZibdOXbQ Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Groups also differed on a cognitive reflectiveness test, and a mediation model suggested differences in reflectiveness partially accounted for greater pruning in the methamphetamine users. The effect of anxiety induction on craving was also positively associated by pruning levels

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

@RENiemeyerPhD Sure, I don’t see why not. Would be interesting to try!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

"The Inter-Personal Affect Regulation Test (IPART): a Performance-Based Assessment of the Ability to Improve the Emotions of Others"

https://t.co/phATcpy09L

Congratulations to co-first author Claire Lavalley on validating this new performance-based measure!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

We expect greater skills in regulating others emotions will be crucial for an individual to maintain social support, which is especially important for individuals with emotional disorders and other forms of psychopathology.

We hope others will also find this measure useful!

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

@Ella_Maru @molpsychiatry Thanks! Great question. People with high trait anxiety experience anxious states more frequently, leading to development of compensatory strategies. So our thought was that anxiety induction might interfere less with reflective cognition in these individuals as a result.

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

Very excited to congratulate Ning Li and Claire Lavalley on their new paper published in @molpsychiatry.

"Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders" (https://t.co/zcf6gik6a1) 🧵👇

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

An important note - an earlier preprint from this study instead reported that anxious depression showed elevated directed exploration than HCs that was reduced by the anxiety induction. This was due to a coding error we caught during revision. We apologize for this error.

[Ryan Smith (@rssmith.bsky.social) @RyanSmith_LIBR]

In this model/task, the slower learning rates suggest that uncertainty in anxious depression may have reduced at a slower rate. Big thanks to our co-authors: @NRDlab @KhalsaLab @mpwpaulus @AnnieChuning @SamuelTaylorCS @CarterMGoldman @rowan_hodson @LIBR_Tulsa