How thrilling to see this online after 8 years in the works!!!
We showed that #Lyme bacteria
mimic our own“don’t eat me” signal with their P66 protein to hide in plain sight!!! This tricks our SIRPa protein to trigger the breaks on immune clearance!
https://t.co/jxdc0xJVjr
The measure of what makes a good medical student and future physician should not be how many publications they have, but how well they understand and care for their patients. https://t.co/KQK4cphJgW
Thank you so much @GlobeKayLazar for this fantastic piece on our clinical study MAESTRO and the impact that it's going to have on our understanding of infection associated chronic illness!
https://t.co/OBK1Bi3iBJ
@ImmunoFever@ndchiappini@bleeeve243@PaigeSHansen@LiLiLac_F We’ve had similar experiences to both of these stories 😂
Finding a newborn mouse left behind on a microscope, and don’t get me started on questionably labeled mouse parts!!
Our bay was Halloween-themed all year.
1/ Taking a break from #COVID, I am going to dig into our new preprint by @StrauszSatu et al! We found some key genes that could protect people from #Lyme disease. Then, we wanted to see if these genetic findings held up in the lab (SPOILER THEY DID!!!) 🧵
https://t.co/1WNjbFcu11
Have you ever wondered what factors affect risk for #Lyme disease? Our new study in @finngen_fi finds two host factors that affect disease risk: one at canonical immune locus, HLA, and one at a quite unexpected locus, SCGB1D2! https://t.co/yQkZw4bSnr
With COVID, and all infections:
Symptoms occur for at least 2 VERY different reasons
1) Immunity Fighting the infection (fever, congestion)
2) The infection winning & causing harm (lose smell, breathing issues)
Symptoms do NOT define if you are infectious, the virus does!
1/
Does it matter if you’re sweating at the time you get a tick bite?
Do you have #Lyme fighting proteins in your sweat?
Check out our latest preprint with @HannaMOllila where we take a deep look at the genetics of people who get Lyme disease.
https://t.co/1LZNNP1rza
@ACK025@ImmunoFever@Irnov_I@JacobsWagnerLab@RavehTaltal @markovic_max @StemCellBear @ErinSandersNP Masts cells too! In the mouse model, we see increased mast cell degranulation in Lyme arthritic tissue, and induced degranulation worsens arthritis.
We’re working to further show mast cell degranulation in Lyme, outside of arthritis.
We have got another big reveal for you #AAI2022! We're determined to take this poster session by storm!
Come talk to @Sarah00Galloway about her incredible work on allergic responses to the bacteria that causes Lyme disease!!! An allergy to bacteria??? What a wild microbe!!!
COVID Update: COVID may not be remembered primarily for the full hospitals, unpredictable variants, mask & vaccine controversies, or even the massive loss of life.
It may be thought of primarily as chronic disease affecting 10s of millions. 1/
I regraphed some of the residual Omicron/B.1.1.529 neutralization data from our recent preprint. This makes a very strong case for getting a booster dose and for getting vaccinated if you are convalescent but not yet vaccinated.
https://t.co/yb20sidGnl
New | Estimating salivary carriage of #SARSCoV2 in nonsymptomatic people & efficacy of mouthrinse in reducing viral load. #COVID19
All 4 mouthrinses decreased viral load by 61% - 89% at 15 minutes & by 70% - 97% at 45 minutes. https://t.co/i4tDcEzgMh cc @DrJudyStone@ImmunoFever
I feel so lucky to have the most amazing team working with me through this rollercoaster of a year. It's been a non-stop 48 hours collecting reams of data on precious mice and LymeTeam rocked it! @Sarah00Galloway@PaigeSHansen @GeorgieNahass @bleeeve243@gumby707@ShulmanSalomon
In September we saw the tweet below. As of today, after lots of hard work, @GeorgieNahass in my group has built us our very own dSTORM. Thank you so much @beniroquai for sharing this with the world! We can't wait to start playing around with it!