Sarbari Saha

PhD student _Trying to understand mechanics of the intestinal epithelium @_andrewgclark @uni_stuttgart. Formerly: @goetheuni @ccmb_csir @nitrourkela

[Organoid News @organoidscience]

🧪 Scientists and Dr. @HansClevers at @_Hubrecht incorporated the integrin-binding domain of Yersinia Invasin protein into polyisocyanide hydrogels, creating a multivalent 3D Invasin environment for long-term culture of epithelial organoids.

@PNASNews | https://t.co/oyZJqj4Pus

[Intestinal Cell News @Intestinal_Cell]

Let's hear it for number two! 🥈

Congratulations to researchers at @Roche, whose work illustrates the potential of spatial transcriptomics to resolve #CRC molecular heterogeneity. 🤩

https://t.co/PfudGUSV9w

[Organoid News @organoidscience]

🥉 Our 3rd top post is here!

Dr. @SamreenJatana and team showed that hyperglycemic stress increases protein loss and disrupts the spatial distribution of intestinal barrier proteins in an intestinal organoid model.

https://t.co/fFVvqXBemV

[Organoid News @organoidscience]

The countdown hits #4! 🔥

The @penningerlab presented a viable organ-on-chip model to vascularize diverse biological 3D tissues, paving the way for organoid perfusions using advanced microfluidics.

https://t.co/SLPRw3wv6f

[Organoid News @organoidscience]

This new study by Drs. @chris_zdyrski, @trtlevoecognmcs, and team presents the development and characterization of adult stem cell-derived turtle liver #organoids from painted, snapping, and spiny softshell turtles. 🐢

@CommsBio | https://t.co/q6dEut1q3i

[Joram Mooiweer @JoramMooiweer]

Co-cultures of Intestinal Organoids and T cells show
IFNγ reprograms intestinal cells, boosting CXCL11-driven T-cell migration! 🔬 Suggests targeting CXCL11 an option to fight inflammatory diseases and GVHD 🧬#Organoids #Immunology #GutHealth
https://t.co/Iwp6498tpH

[Hans Clevers @HansClevers]

Exciting study! Organoid models reveal a novel role for human tuft cells in gut regeneration upon damage. Video: Tuft cell division is triggered by IL-4, visualized in human gut AVIL-Clover reporter organoids (Credit: Daniel Krueger) https://t.co/gXhem2rw0B

[Jens Puschhof @JensPuschhof]

Great to see the @nociorganonchip perspective on standardizing microphysiological systems out in @natBME: https://t.co/1s3zfDsbKI
Many thx to shared first authors @MoerkensRenee + Dennis Nahon, as well as Christine @MummeryLab for steering the ship and having us on board!

[Institute of Human Biology @IHB_Research]

🔬 Exciting discovery! Isolated tissue-resident T cells integrate back into epithelium of intestinal #organoids. Just out in @Nature, this breakthrough engineered #humanmodelsystems recapitulates tissue-mediated immune responses observed in clinic. Paper👉https://t.co/Gein2mZRsD

[soft/living matter fanclub @softlivmat_fc]

J.-Q. Lv, et al., Active hole formation in epithelioid tissues. Nat. Phys. 1–11 (2024). https://t.co/AhhpuKIqvo

[Adam Grant @AdamMGrant]

It's possible to be sexist without being hostile toward women.

Benevolent sexism is viewing women as warm but weak. It limits them to traditional gender roles.

We have to stop pigeonholing people based on their group. Gender is not a valid proxy for competence or character.

[Xavier Trepat @XavierTrepat]

A collection on Mechanobiology 👇

[Tanentzapf Lab @TanentzapfLab]

In science we are in denial about how, like in everything else in life, a huge part, maybe the largest part, of being successful is just being the right person at the right place at the right time. Instead we pretend it's all about being a genius & hand out prestigious awards.

[Sarbari Saha @SarbariSaha1]

An incredible mechanobiology course with great line of speakers @institut_curie (for especially like us who doesn't hold a biophysics background). Huge applause for the organizers @DMVlab, Guillaume Montagnac, Stephanie Miserey. One of an experience !

[Adam Grant @AdamMGrant]

Productivity is overrated. What counts most is the quality of output, not the quantity.

People may be impressed by the volume you produce, but impact depends on the value you create.

Success isn't about getting more things done. It's about doing more worthwhile things well.

[Dr. Nicole LePera @Theholisticpsyc]

If you’re always trying to read people’s emotions or wonder if someone is upset with you, you might have an insecure attachment style.

HERE’S WHAT THAT MEANS 🧵:

[Organoid News @organoidscience]

Congrats to Dr. @HansClevers on his new @CellStemCell paper! 🎉

It presents an optimized #protocol for culturing human small intestinal #organoids, and uses them to reveal the interleukin-22-dependency of paneth cell formation.

Learn more: https://t.co/cpETeN3dQ3

[Andrew Clark @_andrewgclark]

Congratulations to @SarbariSaha1 for having her image of a mouse intestinal organoid selected as an honorable mention in the 2022 @zeiss_micro microscopy image contest! https://t.co/8kjyTuRNyO

[John Streicher @JohnStreicher1]

If you think abuse is "very rare" in academia then this most likely means none of the students trust you enough to tell you about it.

[Nature Physics @NaturePhysics]

Transepithelial potential difference governs epithelial homeostasis by electromechanics

https://t.co/ALabJEEab9