Check out my recent publication in bioRxiv.
Thank you so much to my mentor Dr. Ali Mortazavi as well as the co-first author Dr. Shan Jiang!
Comparative Chromatin Dynamics of Stem Cell Differentiation in Human and Rat https://t.co/cVgUz3IBgr
Extremely pleased to share the preprint of our paper on single-nucleus RNA-seq in FSHD. Thank you to everyone who has been a part of it. I hope this work helps others and their research. @ShanMandy#SingleNucleus#SingleCell#RNAseq#FSHD#DUX4
https://t.co/eVn125oAan
I am happy to share another example of how long reads can outperform short reads for functional genomics! Great collaboration with @SpitaleLab .
Long-TUC-seq is a robust method for quantification of metabolically labeled full-length isoforms https://t.co/HabBw9htw3
Check our latest @nature paper here:
https://t.co/Zo0VZ1zHQV
Circular ecDNA promotes accessible chromatin and high oncogene expression
We reveal the circular shape of extrachromosomal DNA in cancer, describe its transcription, chromatin landscape, and 3D interaction @mischellab
The international #HumanCellAtlas General Meeting is starting tomorrow, October 10 - 11, 2019. See full agenda here: https://t.co/Cq6rpqFAHv. Talks and breakout sessions will be livestreamed at https://t.co/RHbifxYIcS
The hypothalamus can become inflamed during aging and in metabolic diseases. Cai and Khor provide an overview of mediators, signaling components, and physiological impact of hypothalamic microinflammation. https://t.co/wP5kPMtx8n
Are you interested in spatial transcriptomics? Check out our new Giotto pipeline for analysis and visualization! Great work by @RnDries@qzhu2012 and collaboration with @LongCai_Lab https://t.co/eKLeXmvxYi
how about a predictive marker of vulnerability or resilience to mental illness? after early-life adversity? methylation profile? but variance between people is a problem check out a solution in experimental models. Human babies coming soon...
At long last, I am glad to share our pipeline for long-read RNA-sea using @PacBio and @nanopore sequencing for the @ENCODE_NIH Consortium.
This has been the hard work of the two first authors- Dana and Gaby- over the last two years.