Shaobo Zhang

ucsf

[Martin Smith @martinalexsmith]

How cool is this? Michal Lipinski from @broadinstitute presenting stacked #Illumina spatial slides of the mouse brain with subcellular transcriptome resolution #AGBTGM

[Li Wang @LiWang_neuro]

Brain cancer leverages the same tools as the developing brain 🧠! In our new study, published today in @Nature, we mapped neocortical development to explore brain cancer and neuropsychiatric risks. #stemcells #brainresearch
https://t.co/8t8WHyQiS4

[Shaobo Zhang @ShaoboZhang6]

@mo_hannes @Caltech @CaltechCCE Congrats！！

[Rong Fan @RongFan8]

Spatial epigenome–transcriptome co-sequencing🤩🤩🤩Beyond excited to see it out today @Nature! Enjoyable collaboration between my lab @YaleBME @YaleSEAS @YaleMed and @GoCasteloBranco of @karolinskainst. The most informative tool for spatial multi-omics!!
https://t.co/hRTtfGVbno

[Matt Henderson @matthen2]

Check out UMAP - it tends to do better at preserving the actual structure https://t.co/cJC6kDUzzB

[Nature Medicine @NatureMedicine]

New Perspective: Russell van Gelder & colleagues discuss promising strategies for restoring visual function in degenerative retinal disease - including cell-based therapy, gene therapy & prosthetics.
@UWMedicine @NatEyeInstitute @NEIDirector @CliveSvendsen
https://t.co/lDd4hWsEmL

[Saez-Rodriguez Group @saezlab]

We are 🥳 to share that a substantially improved version of LIANA’s manuscript "Comparison of Resources and Methods to infer Cell-Cell Communication from Single-cell RNA Data" has now been published at: https://t.co/Tdy1MOkCPz

Highlights for some of our findings in the 🧵1/10

[Jiefu Li @JiefuBiol]

We are hiring @HHMIJanelia
systems cell surface biology, neuro, immune, method development
https://t.co/6dSbsAKrgQ

[Jiefu Li @JiefuBiol]

We are hiring @HHMIJanelia!
systems cell surface biology, neuro, immune, method development...
https://t.co/6dSbsB1uiQ

[Gray Camp @GrayCampLab]

Space-time analytics in digital human organoids! Stellar work from talents @WahlePhilipp @brangiov @HarmelChristoph @zhisong_he + team! Collab with @lucaspelkmans @TreutleinLab. Thanks @OrganoidAtlas @cziscience @humancellatlas @ETH_BSSE @IOB_ch #organoids https://t.co/DxqNpmCLJ7

[Fabian Theis @fabian_theis]

Interested in spatial omics? Plz check out our squidpy tool, bringing together omics & image analysis to enable a scalable description of spatial molecular data. Out today @naturemethods thx to @g_palla1, @HannahSpitzer1 & team! https://t.co/0iD92imm4H https://t.co/VPpelQHzl1

[Science Magazine @ScienceMagazine]

New in Science: Researchers present a high-speed cell sorter that records multicolor fluorescence images and sorts cells based on them at speeds upwards of 15,000 events per second. Learn more ➡ https://t.co/KIZLQZ2Sce

[Angelique C Paulk @ACPaulk]

As promised, we put 3 deidentified human Neuropixels data sets up on DRYAD! Thanks to all the participants and Yoav Kfir, Ziv Williams, Syd Cash and coauthors! #OpenData #Neuropixels @sergeydoestweet @EricMTrautmann @shenoystanford
@MGH_CNTR @MGHNeuroSci
https://t.co/pKsqEbjhUX

[David R. Liu @davidrliu]

Today we report in @CellCellPress an engineered virus-like particle (eVLP) platform that mediates efficient in vivo delivery of therapeutic proteins, including base editors and Cas9 nuclease, resulting in therapeutic editing in multiple mouse organs. 1/14
https://t.co/v1yBl296L6

[Nature Methods @naturemethods]

A new benchmarking study compares 16 methods for integrating complex single-cell RNA and ATAC datasets and provides a guide to method choice. @MDLuecken @fabian_theis @colomemaria_epi @ICBMunich @HelmholtzMunich
https://t.co/AC2ydb1gL5

[Abu Sufyan @abusufyanvu]

"NLP with Deep Learning" by @stanfordnlp is free and open!

Find links on:
- lecture slides
- lecture videos
- notes
- codes
- suggested readings

All is here⬇️
https://t.co/vvoEd0mEKk

[Nature Biomedical Engineering @natBME]

Cancer cells enriched in cholesterol in their plasma membrane impair T-cell-mediated cytotoxicity, which can be augmented by stiffening the cancer cells via cholesterol depletion, as shown in mouse models of adoptive T-cell immunotherapy.

https://t.co/BOgeq9ZDOF

[Nature Neuroscience @NatureNeuro]

Organ-specific targeting (enriched in brain, not liver) of adeno-associated virus (#AAV) capsids after intravenous delivery in mice and marmosets enables new avenues for gene therapy

New from @VivianGradinaru @DavidGoertsen @Caltech @CaltechN

https://t.co/id6WlMEEV9

[Stefan van der Walt @stefanvdwalt]

scikit-image 0.19.0 is out!

👏 to release manager @__GregLee__

Highlights include:
- SIFT keypoints
- Blur metric
- Lazy loading
- Pixel graphs

Also some beautiful new 3D bio examples in the gallery! (🙏 mkcor)

Check out the full release notes at https://t.co/y04yrOpZRe