@DKFZ postdoctoral fellowship awardee & @TMO_Heidelberg team member excited about unraveling targetable vulnerabilities in sarcomas | @NKI_nl & @zwartlab alumni
Beyond excited to finally share our new publication in @CD_AACR, in which we show how prostate cancer cells hijack circadian rhythm regulators to sustain proliferative potential upon AR blockade. A true team effort! @zwartlab @NKI_nl@oncodeinstitute
https://t.co/HwFhc2T8eV
🧵⬇️
Latest journey in #prostatecancer cell plasticity. Team effort @ChrisSweens1@kat_morel@BeatrizGerFalc
Work stems from previous @ChrisSweens1 investigations in NFkB regulation by tristetraprolin (TTP; gene ZFP36), and generation of the NFkBi dimethylaminoparthenolide (DMAPT)
@CancerCoreEU brachte vom 6. - 11.10. erneut Nachwuchskräfte und Expert:innen aus der Krebsforschung an der Algarve zur CCE Summer School in Translational Cancer Research zusammen.
Das NCT Heidelberg war dabei stark vertreten.
Hier zum Rückblick https://t.co/orVTt0FlJQ
🚀 Excited to share another successful CCE Summer School in Translational Cancer Research! ☀️🥼 A huge thank you to everyone who contributed to making #CCESummSchool24 memorable.
➡️ https://t.co/sKtBTt1u8c
Had an amazing time at #CCESumSchool24 in Albufeira, representing @NCT_HD and @DKFZ! A week of inspiring talks, hands-on workshops, and connecting with brilliant scientists from top EU cancer centers.
Thrilled to win the best participant talk prize! Big thanks to @CancerCoreEU!
Congratulations to the stellar @DKFZ PostDoc @Simon_Linderson for winning the award for Best Participant Presentation at #CCESumSchool24! 🎉🏆 He gave a talk on how enhancer hijacking events upregulate genes that could serve as targets for novel sarcoma therapies. @CancerCoreEU
Ever wondered how transposable elements are used differently across development and towards oncogenesis - We provide insights on their role as regulatory elements across pluripotent, mature and cancer cells, with a focus on prostate cancer: https://t.co/Lymvhl6XEn
Please RT: We are hiring informaticians for HEROES-AYA (https://t.co/yANB93iYPF), a multicenter program within the @XgegenKrebs that aims to understand and target tumor heterogeneity and evolution in adolescents and young adults with #sarcoma.
https://t.co/TgzQU3mkTa
So proud of @IsabelMayayo who brilliantly defended her PhD! 🎓 As her co-promoter, alongside @zwartlab, at @NKI_nl, I've witnessed her unwavering determination & exemplary work first-hand. Excited for the brilliance her future holds! #WomenInSTEM#ProudMentor#AcademicChatter
1/3 Are you struggling with different Hi-C data analysis and the handling of different input formats for different tools? Have a look at 𝘴𝘯𝘏𝘪𝘊: the new @zwartlab snakemake Hi-C pipeline, now published on @BioinfoAdv!
DOI: https://t.co/eHTTerYJmQ
https://t.co/JyE2yCZ0PJ
🧬1/ How do SHRs regulate transcriptional activity, and which components of the SHR-coregulator complex are essential for transcription? Our study, published in @NAR_Open, used a FACS-based CRISPR screen to dissect the GR complex. https://t.co/vR3wOXfh76 🧵
Super happy to have received the award for the best basic/translational abstract at the Dutch Endocrine Meeting 2023! Many thanks to all organizers for putting together such a stellar conference! 🧬🧫 #DEM2023@NVEndo
Many thanks to Leonie Young, @damirvareslija and @donaldmcdonnell for giving me the opportunity to present my @zwartlab PhD research on acquired prostate cancer vulnerabilities in the Young Investigator Session at the @Endoadapt Dublin Steroid Cancer Conference @RCSI_Irl. 🧬
I’m very happy to have received the best poster price at the @EMBO#NuclearReceptors meeting in beautiful Malta, where I presented our latest @zwartlab research. Kudos to @JCarrollLab and all other organizers - it was absolutely amazing. 🧬
Excited to share our work on "cistrome-wide association studies" (CWAS) in @NatureGenet. #CWAS identifies #GWAS variants that influence traits and diseases through local effects on the #epigenome. https://t.co/AOyJEPLhml