@JDubwub @cryptoklotz Ascvd is caused by particles penetrating the endothelial lining and sparking an immune response to remove the particles that lead to fatty streaks / plaque
The more LDL carrying cargo ships you have, the more likely that more particles will penetrate, and lead to more plaque
@JDubwub @cryptoklotz Maybe we’re generally arguing the same thing that particle count is more important than concentration.
The one image you shared showing greater particle count with increased risk I agree with. ApoB is the best metric we have IMO, because it counts the cargo ships carrying ldl