Stoyno Stoynov

Group leader, Laboratory of Genomic Stability, Institute of Molecular Biology, BAS #DNArepair #DNAReplication #Imageanalysis #Cancer #Anticancerdrug #Microscopy

[Cell @CellCellPress]

Now online! Polarity-guided uneven mitotic divisions control brassinosteroid activity in proliferating plant root cells https://t.co/KSZMwHvMYc

[Laboratory of Genomic Stability @LGS_IMB]

How many PCNA/RPA molecules are loaded and removed per min during fork stalling and restart? How do DDR inhibitors influence these dynamics?
We estimate these rates in our pre-print, out on bioRxiv: https://t.co/51hfXZSL39
#microscopy #DNArepair #genomestability #DNA #replication

[Petar Kanev @petkanev]

Contributing to efforts toward elucidating the response to replication stress, we provide a precise timescale of fork stalling and restart in live cells, at 30-s resolution (airyscan teaser below). https://t.co/cvLW0YaI5O
#replicationstress #DNArepair #ATR #replication #DNA #RPA

[Radoslav Aleksandrov @radaleksandrov]

We are happy to share our latest paper “A unified mechanism for PARP inhibitor-induced PARP1 chromatin retention at DNA damage sites in living cells”, out today in @CellReports. #PARP1 #PARPinhibitor #GenomicStability

Hopefully not a boring thread ↓

https://t.co/MCU6BsbJRQ

[EMBL @embl]

The @EU_Commission has officially established @EuroBioImaging as an European Research Infrastructure Consortium (ERIC).

Euro-Bioimaging provides life scientists with #openaccess to a range of technologies & resources in biological and biomedical imaging: https://t.co/Y6p4ct1bgW

[Mihail Sarov @MihailSarov]

I am very proud of the latest output of our lab - the Master of Molecular Bioengineering Irina Georgieva!

[IMP @IMPvienna]

Research highlights of the past year? @QuantaMagazine has included the #axolotl genome in its compilation: https://t.co/LAc2FXo0RF
@IMPvienna @viennabiocenter @mpicbg @csbdresden @CRTDpress

[bioRxiv @biorxivpreprint]

CellTool: an open source software combining bio-image analysis and mathematical modeling https://t.co/GSutCozyBG #bioRxiv

[Stoyno Stoynov @StoynoS]

The preprint for our open source software #CellTool for #imageanalysis with simultaneous data presentation was posted on #BioRxiv.

[CellTool @CellTool]

The preprint for #CellTool is available at #BioRxiv. #CellTool is a stand-alone open source software, optimized for measurement of time-lapse #microscopy images. It combines #imageprocessing, #mathematicalmodeling and graphical presentation of data. https://t.co/p4XLrHup4z

[EMBL @embl]

First interactive model of human cell division https://t.co/jvxYGFUA9S

[Mihail Sarov @MihailSarov]

Четири медала за българските ученици от Международната олимпиада по биология https://t.co/M9IOmDrPFN

[Stoyno Stoynov @StoynoS]

Research Reveals Dynamics of DNA Repair Proteins https://t.co/vqMQN9WNBn

[Laboratory of Genomic Stability @LGS_IMB]

It was a great collaboration with @HymanLab, @bel_drag, @TransgeneOme, Stephan Grill, Frank Buchholz, Greta Panova and Georgi Georgiev

https://t.co/86tPJtu5P1

[Laboratory of Genomic Stability @LGS_IMB]

An interview with the member of the lab @radaleksandrov and Anton Dontchev in Meet the Author series of @MolecularCell
https://t.co/zgd8bALwoh

[Laboratory of Genomic Stability @LGS_IMB]

Sentinels of the Genome
https://t.co/NwDs7RvfwO

[Laboratory of Genomic Stability @LGS_IMB]

We are happy to announce that our paper is published as a Featured Article in the current issue of @MolecularCell.
https://t.co/86tPJtu5P1

[Laboratory of Genomic Stability @LGS_IMB]

You can check out and compare interactively the kinetics of 70 DNA repair proteins with and without PARPi reported in @MolecularCell with our web tool https://t.co/12yRW5pRgs