Hard to say goodbye to these two 1st gen Perera lab members 🥺- @AnthonyVenida - off to Stanford for his postdoc and @SupritGupta25 - shown giving his last lab meeting, now at @chemocentryxinc - so proud of all you have achieved. We will miss you 👋
Incredibly grateful to receive the Gunter Blobel Early Career Award. Thank you @ASCBiology for this recognition.
Congratulations to all awardees incl. my former mentor Pietro De Camilli @PDClab who received the EB Wilson Medal ! 🍾🍾🙏 https://t.co/EZEYV5q38Q
NEW online today from @rushika_perera & co: Membrane repair factor Myoferlin protects against membrane damage in pancreatic cancer lysosomes to sustain enhanced lysosomal function and promote tumour growth.
Download the pdf here: https://t.co/RrKzV4fv8F
https://t.co/t8eXfsx5zg
Check out our lab's most recent publication exploring lysosomal biology in PDAC and how it can sustain membrane stress to promote tumor growth!
Congrats to @rushika_perera, @SupritGupta25, @JulianYano and the rest of the lysosome dream team on this @NatureCellBio paper!
Nothing makes a guru happier than the success of his chela!! @SupritGupta25 Proud of you Suprit for the great work publihsed in Nature Cell Biology!! Congratulations!!
https://t.co/kZkb2tI4jR
Excited to announce our work in the lab of @rushika_perera by first author @SupritGupta25 is out in @NatureCellBio ! We demonstrate a unique dependency of Pancreatic Cancer on repair factors previously only found in muscle!
Ferlins to the rescue! Plasma membrane repair protein Myoferlin relocates to lysosomes in pancreatic cancer cells to protect lysosomes against microtears in their membrane. Preprint by @SupritGupta25 and
@rushika_perera lab. Prelight by @BerrakUgur1
Welcoming the new year with a new preprint identifying a cancer specific mechanism for lysosomal membrane stabilization. "Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth". Thread below. 👇1/
https://t.co/kaLZu6jpFz
Congrats to first author @SupritGupta25 and Perera lab teammates @UCSF, and collaborators @HijaiShin@RobertoZoncu@berkeleyMCB and David Dawson @UCLA ! Together we discovered that pancreatic cancer lysosomes are highly resistant to membrane stress. 2/
Saddened to hear about the passing of Irrfan Khan. What a phenomenal talent and dearly touched everyone's heart with his versatility. May god give peace to his soul 🙏