Tom Fusillo, DO

Incoming Chief Resident at @MSKcancercenter | @UTAustin , @NorthwesternLaw , & @DesMoinesUniv Alum | RT ≠ endorsement; I sometimes RT things I don’t agree with

[Tom Fusillo, DO @T_Fus]

@miami_rick Does this take into account Bernoulli effect? Presumably would substantially lower the pressure gradient.

[Jame Abraham, MD, FACP @jamecancerdoc]

Absolutely practice changing!! One of the most stunning developments in the treatment of patients with metastatic pancreatic cancer !! It is one of the rare moments in oncology which you will always remember ! Like the imatinib, trastuzumab presentations @ASCO #ASCO26 @OncoAlert

[Tom Fusillo, DO @T_Fus]

Every week this is the scene right outside my building. Sidewalk overrun with broken pieces of furniture and random objects. Today we also had plenty of broken glass. @NYCSanitation @NYPDnews @nypost We shouldn’t just put up with this. Everyone needs to do their part to keep our city clean and the greatest in the world.

[Spencer Pratt @spencerpratt]

If that addict on your street were your own son, what would you do? That is the defining question that guides my 5 step plan to fix the homelessness problem in LA. We *must* end this evil racket of corrupt politicians and NGOs who profit off the misery of these poor souls. They launder money and feed them more drugs, so they can keep their customers locked in this hell on our streets. We have a moral obligation from God to help them and make our city safe and clean for everyone. Karen Bass and Nithya Raman have forsaken this city. Time for real leadership. Time for real compassion.

[Tom Fusillo, DO @T_Fus]

@GovKathyHochul Great. Will be ready in 35 years.

[Tom Fusillo, DO @T_Fus]

It is more complicated though Congressman. We are crushed by debt and bureaucracy immediately upon medical school graduation. I am planning on a long career in clinical medicine + research but I understand why others do not. I would love to come to DC to meet and discuss further and come up with a plan to fix this problem.

[Memorial Sloan Kettering Cancer Center @MSKCancerCenter]

Memorial Sloan Kettering Cancer Center (MSK) congratulates Dr. Nicole B. Saphier on her nomination to become the next Surgeon General of the United States. Over her decade of service to the MSK community, Dr. Saphier has been a tireless advocate for women’s health and early cancer detection, expanding access to breast cancer screening, and raising awareness at a community and national level. We are grateful for her steadfast commitment to delivering excellent patient care and her willingness to serve our country in this capacity.

[Tom Fusillo, DO @T_Fus]

@kai_xbt I gotta know what physician is prescribing selegiline in 2026.

[NEJM @NEJM]

Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: https://t.co/qAMC2o36Mi

Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? https://t.co/KyOWdblUR3

[Tom Fusillo, DO @T_Fus]

@mcuban @costplusdrugs For those wondering how this drug works

https://t.co/egfz8wJSWp

[Tom Fusillo, DO @T_Fus]

A few weeks ago I had a patient that we considered starting Tikosyn (dofetilide) on. It’s a less common anti-arrhythmic so I did a bit of a deeper dive. 🧵

[Sravan Panuganti, DO, FACOS @SPuro88]

Cool part about being a physician is that you get accused of being a pharma shill & forcing pills down peoples’ throats and get yelled at for not prescribing antibiotics for asymptomatic bacteriuria both in the same day.

[Tom Fusillo, DO @T_Fus]

Taxi ride in NYC today:

Fare: $9.30

Fees: $7.25
Congestion surcharge: $2.50
Rush hour surcharge $2.50
Central business district surcharge $0.75
Taxi improvement surcharge $1.00
MTA State surcharge $0.50

[Anil Makam @AnilMakam]

https://t.co/FPoF1Pt6TC

[Tom Fusillo, DO @T_Fus]

@Nowooski Cefepime?

[Tom Fusillo, DO @T_Fus]

@AmmousMD I'll add that sure, their hypothesis of mental stress causing HTN causing plt activation in theory may have an effect, but they chose not to reference or site anything to support this. Why?

[Tom Fusillo, DO @T_Fus]

The authors in that paper suggest that mental stress causes more ASCVD than actual plaque. How does that work?

"Here, the authors found that LDL-C was significantly higher among those with subclinical atherosclerosis (125.7 vs.117.4 mg/dl). However, association does not prove causation. Mental stress, for instance, is able to raise cholesterol by 10–50% in the course of half an hour[18,19], and mental stress may cause atherosclerosis by mechanisms other than an increase in LDL-C; for instance, via hypertension and increased platelet aggregation."

Hundreds if not thousands of studies have supported LDL increasing ASCVD risk. Here's a more recent one from 25 years of data:

"During follow-up (mean: 5 years), the early target LDL-C group (n = 5702) had a lower risk of recurrent MACEs compared with the non-early target LDL-C group (n = 11,232; adjusted hazard ratio [95% CI]: 0.89 [0.82–0.96]). The effect was most pronounced in patients with ACS (0.73 [0.63–0.85]), particularly for recurrent MACEs within 6 months (0.61 [0.44–0.87]). The early target LDL-C group had 19% lower frequency and 31% shorter LOS for cardiovascular-related hospitalizations than the non-early group."

https://t.co/Va7e0C1Fx2

[Tom Fusillo, DO @T_Fus]

@Papa_Heme I use it occasionally for lit review but the problem I have had when asking about differentials or management decisions is that its responses differ somewhat substantially depending on how the question is phrased.

[Secretary of War Pete Hegseth @SecWar]

The Department of War has officially put Scouting America on notice.

It’s time to get back to basics — and DoW is leading the charge.