Tacke Lab

Research group studying liver immunology and gut-liver interactions, acute and chronic liver diseases. #liver #immunology #immunooncology #inflammation

[eGastroenterology @eGastro_BMJ]

🙌 This review summarizes recent findings deciphering the relevance of liver macrophage spatial localization as a phenotypical marker and functional contributor to liver diseases.

via https://t.co/h0GDWVFVdP

@bmj_company @Tacke_lab @FrontGastro @FrankTacke

[eGastroenterology @eGastro_BMJ]

A review paper by Prof Frank Tacke & Dr Adrien Guillot entitled

‘Spatial dimension of macrophage heterogeneity in liver diseases’ via

https://t.co/UzIWeigwnc

[Tacke Lab @Tacke_lab]

Now in the latest Hepatology issue! Thanks to all contributors and collaborators!
https://t.co/AKvyob1l8n
Multiplex immunostaining revealed that accumulation of IBA1+ CD16lo CD163lo macrophages near ductular cells is a hallmark of advanced liver disease (incl. NAFLD, PSC).

[Tacke Lab @Tacke_lab]

What are the mechanisms of fibrosis across organs and disease etiologies?

💡Our latest review examines the underlying processes and resulting therapeutic opportunities. @ILurje

https://t.co/2YGF6uGIsA

[Tacke Lab @Tacke_lab]

@kaymtye @science_is_hard Holy crap! What a nightmare......I hope it's not broken beyond repair.....what a major blow :(

[Tacke Lab @Tacke_lab]

Ever wondered why CXCR6+ cells in the liver are important? Check out our latest article showing that loss of CXCR6 exacerbates inflammatory IL17 responses in liver!

Hepatic C-X-C chemokine receptor type 6–expressing innate... : Hepatology Communications https://t.co/xb3lmVuJLF

[Linda Hammerich @Flt3Linda]

@KimberlyHartl_ @JohannaKusnick @Tacke_lab

[Tacke Lab @Tacke_lab]

Check-out two recent reviews from our department and collaborators on the diverse roles of immune cells in primary liver cancers! Big-up to #MarleneKohlhepp
@Branden_HY_Liu @YeniAit #FouadLafdil #AdrienGuillot @Tacke_lab

📌 https://t.co/3q6jDtgDmW

📌 https://t.co/h2ja5qMqHt

[Linda Hammerich @Flt3Linda]

Happy #WomenInScience Day!

So greatful for this team of powerhouse woman scientists that slay every single day. Let's keep this going @ILurje @JohannaKusnick and the whole twitter-less bunch @Tacke_lab

[Tacke Lab @Tacke_lab]

Congrats to our PI #AdrienGuillot advocating for science and research! Hooray for the Franco-German friendship! #GenerationEU @ofaj_dfjw @AllemagneDiplo @EmmanuelMacron @Bundeskanzler

[Tacke Lab @Tacke_lab]

We are thrilled to announce that the members of our lab Adrien Guillot and @ilurje together with Prof. Fouad Lafdil will edit the Special Issue "Tumor-Associated Macrophages in Primary Liver Cancers and in Premalignant Liver Diseases". We look forward to your submissions!

[Linda Hammerich @Flt3Linda]

Just some of our rising stars (@JohannaKusnick AlixBruneau) having fun presenting their data at the annual meeting of @Ferroptosis2306 #ferroptosis #immunogeniccelldeath #curinglivercancer

[Tacke Lab @Tacke_lab]

Happy and proud to fond our name here again this year #HighlyCited2022 https://t.co/3jJFMOZEYf this is a team effort!!

[Tacke Lab @Tacke_lab]

Congrats to all #HighlyCited2021 Researchers at #CharitéBerlin! Proud and happy to find our name on this list 🤗

[Tacke Lab @Tacke_lab]

and @olmohsin and @Flt3Linda

[Tacke Lab @Tacke_lab]

Congratulations @CorneliusEngel7 !

[Journal of Hepatology @JHepatology]

🆕Article in press❕

Combination of G-CSF and a #TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of #ACLF

Read it here👉https://t.co/ZG9wQwr1Mn

@CorneliusEngel7
#LiverTwitter

[Tacke Lab @Tacke_lab]

https://t.co/loFsleOTWY

[Journal of Clinical Investigation @jclinicalinvest]

#Cover: Distinct histopathological phenotypes of severe alcoholic hepatitis: https://t.co/JRMKhYi6Qp
Image: multiplex immunofluorescence staining of liver tissue with SAH, revealing a large number of inflammatory cells surrounding hepatocytes
@NIAAAnews
#Gastroenterology

[Tacke Lab @Tacke_lab]

Our collaboration with Bin Gao’s lab just released in JCI: two distinct histopathological phenotypes based on liver immune phenotyping observed in severe alcoholic hepatitis patients
Our multiplex IHC is on the cover @Tacke_lab #AdrienGuillot @NIAAAnews
https://t.co/EgBv7ZY2LD

[Moritz Peiseler, MD @moritzpeiseler]

Delighted to see our review on immune cell heterogeneity in #NAFLD in the era of multi-omics in press at @JHepatology! Thanks to invaluable contributions from @CancerInflam, @RobSchwabe, @Kubes_Lab, Jochen Hampe and of course @Tacke_lab!
#LiverTwitter

[Isabella Lurje @ILurje]

Read now in „Liver Cancer“:
❗️single-nucleotide polymorphism of CXCR1 is associated with oncological and overall outcome in surgical CCA patients❗️
https://t.co/9QGplQuk8b
@glurje @ZoltanCzigany @Tacke_lab @ChariteBerlin @KargerPublisher

[Linda Hammerich @Flt3Linda]

Our master's student just won a speed lecture award talking about her research studying #ferroptosis in #livercancer. So proud!! Congrats @JohannaKusnick @Tacke_lab @Ferroptosis2306 #BIONNALE #fireuptheliver