Holley Lab

The Holley Lab at Duke University works to discover how non-coding RNAs and epitranscriptomic RNA modifications contribute to heart disease.

[Sudarshan Rajagopal @SudarRajagopal]

@NIH While the indirect rates have in general been to high, it reflects that the direct costs have not been inflation-adjusted for decades. If you do this, put the money back into direct costs that actually fund the research. This is a total disaster for all universities.

[Harlan Krumholz @hmkyale]

NIH just made a drastic change to indirect cost rates, reducing the rate to 15%, a significant cut from the 60%+ some institutions charge. This will have a devastating effect on the nation’s medical research infrastructure. @ResearchAmerica @AAMC @YaleMed https://t.co/GQidBBR6C8

[Prof. Akiko Iwasaki @VirusesImmunity]

NIH indirect costs fund the backbone of research: maintaining labs, ensuring safety, and supporting admin work. These are essential for groundbreaking discoveries. Drastic cuts to NIH indirect rates are detrimental to academic biomedical research.

[F. Perry Wilson, MD MSCE @fperrywilson]

NIH has announced a cut in the "indirect rate" to 15% across the board, in a move that appears to be retroactive to even existing grants. This is a bloodbath for research institutions throughout the country.
Brief explainer for those not in this world:

https://t.co/VUP7tWat7O

[Jeffrey Flier @jflier]

This approach to suddenly cutting @NIH grant indirect costs will cause chaos and harm biomedical research and researchers in hospitals, schools and institutes nationwide. A sane government would never do this.

[Andrea C. Love, PhD @dr_andrealove]

The NIH 15% cap on indirect costs will kneecap biomedical research in the US.

Without essential infrastructure, there will be:

Staff cuts
Lab closures
Fewer research projects
Less scientific progress
Loss of talent

The US will no longer lead scientific & medical innovation.

[MeyerLab @MeyerLabDuke]

Attention prospective postdocs: Are you interested in studying RNA modifications and using cutting edge technologies to uncover the role of m6A in physiology and disease? Come join our team! We are hiring!
https://t.co/0Za5MdqPGt

[Syed A. Ahmad @SyedAAhmad5]

Medical knowledge is doubling every 60 days.

There are no shortcuts for training physicians.

MEDICINE IS DIFFICULT AND SERIOUS BUSINESS. 👇🏼👇🏼

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

[Sean M Wu, MD PhD @SeanM_Wu]

Great visualization and a nice way for trainees to see what it takes to make it as an academic scientist. 👍👍👍🙏🙏🙏👏👏👏

[MeyerLab @MeyerLabDuke]

Excited to share our latest work developing DART transgenic mice and using them to profile m6A in single cells of the mouse brain. A fantastic study led by Matt Tegowski with contributions from @TheHolleyLab https://t.co/2OSfKmtiW1

[Holley Lab @TheHolleyLab]

@SvatiShah @robmentz @manesh_patelMD @Nishant_ShahMD @senthil_selv @MEbreitbach @aepetersMD @SJGreene_md Nice work - I hate those shrubbery nets!! My daughter and her ball python also applaud your good deed. 😃

[Pradeep Natarajan @pnatarajanmd]

Are you an MD student interested in research?
Would strongly consider applying for the @SarnoffCardio Fellowship. Scientific immersion with *unparalleled* longitudinal mentorship & exceptional peer network career-long. https://t.co/v8Hz9bxwYC
My biggest regret in med school was not participating despite guidance from mentors. Now I'm thrilled to join this vibrant community on the Scientific Committee.
Nice summary of the program https://t.co/GE79jX8RUW @CircAHA
Track record of successful physician-scientists going through this program is impressive - the recipe of immersion + longitudinal engagement/sponsorship/mentorship works very well

[Holley Lab @TheHolleyLab]

@MuathBishawi @DukeCTSurgery @DukeSurgery @DukeHeartCenter @JacobNiall @EmoryCTSurgery @GeorgiaTech Congrats Muath - will miss you and wish you the best of luck and success at Emory and GA Tech!

[The RNA Society @RNASociety]

RNA science has gone mainstream - learn from outreach experts how to best explain your research in a way that the public actually understands! 

Join us for the Public Engagement in RNA Research Workshop scheduled just prior to RNA 2024 in Edinburgh. Registration required and the deadline for joining is tomorrow, May 16th!

https://t.co/0ofX1prCEt

[Chad Pecot, MD @ChadPecot]

Learned so much from @KatherineZhouMD and @TheHolleyLab putting this together

Keep an eye out for Katherine, she's a fantastic scientist!

More to come soon 🧐 @RNADiscovery @UNC_Lineberger @chrisholley

[JAMA @JAMA_current]

Most viewed in the last 7 days from @JAMA_current:

New USPSTF guidelines recommends all women undergo routine #breastcancer screening every other year beginning at age 40, an update from the 2016 recommendation to start at age 50.

https://t.co/lRQEU6s0Q4

[Holley Lab @TheHolleyLab]

Exciting work with translational promise from the Holley and Freedman labs, presented at #AHA23 by Brittany Elliott, PhD:

[Holley Lab @TheHolleyLab]

@ChadSWeldy @StanCVFellows @euanashley @joshuawknowles @alyelezaby Congrats Chad!

[American Heart News @HeartNews]

Manesh Patel followed his dream of making a difference, and to him, it’s a privilege. #AwardsWithHeart Read his full story: https://t.co/Gi4NsErplD @manesh_patelMD @AmericanHeartNC