Jae Lab

Functional genomics lab at the LMU Gene Center in Munich, Germany. -Posts by LJ

[Jae Lab @TheJaeLab]

@XiangZh04660352 @GeneCenter_LMU @LMU_Muenchen @PichlmairL @MPI_Biochem @ERC_Research @dfg_public If you’re into heme, also check out this intriguing study by our friends @Riemerlab on the spatial choreography of a key step in heme synthesis, also featuring an evolutionary plot twist: https://t.co/mKBNIp0j71

[Jae Lab @TheJaeLab]

Check out our new @Nature paper showing that heme scarcity is surprisingly sensed in #mitochondria by the #DELE1 pathway. Conserved all the way to Hydra, this ancient system takes the heme reading in the very organelle that produces this key metabolite. https://t.co/Si8r5fPT6u

[Jae Lab @TheJaeLab]

Spearheaded by @XiangZh04660352 and Max-Hinderk Schuler here at @GeneCenter_LMU @LMU_Muenchen, with fantastic collaborators: team @PichlmairL and Barbara Steigenberger @MPI_Biochem. Deeply grateful to our funders @ERC_Research, @dfg_public, Krupp Foundation and Vallee Foundation.

[Irina Dudanova @IrinaDudanova]

Our joint study with Takaki Komiyama @takaki_komiyama is out in @Nature !
https://t.co/bW0tvl9cao

We found cell type-specific changes in the cortical circuit of Huntington’s disease mice. Optogenetic stimulation of VIP cells rescued circuit defects and improved motor function.

[Till Stephan @stephan_till]

📢 We are hiring!

My lab is looking for a postdoctoral researcher. If you are excited about understanding cholesterol transport between the endoplasmic reticulum and mitochondria, membrane biology, lipid metabolism, or super-resolution imaging, please apply by June 30th!

[Jae Lab @TheJaeLab]

Big news this week: results of a very competitive @ERC_Research CoG call are in, and I’m happy that our project mitoSCALES (scales of mitochondrial stress response) is among the ~11% funded. Recruiting will begin soon—get in touch if you want to hop on board for the ride!
#ERCCoG

[Jae Lab @TheJaeLab]

@DeshwalSoni @HelmholtzMunich @ERC_Research @Conrad_Lab @SchmollerLab @NatalieKrahmer Cool! Congratulations and welcome to Munich

[Jae Lab @TheJaeLab]

@BarteltLab Congrats, wonderful news! 🤩

[QMB Munich @MunichQbm]

📣Only three weeks left to apply! Exciting projects with renowned scientists are available. Don’t miss your chance! https://t.co/af3syVPeiD
@TheJaeLab @karen_alim @PhysOfLifeLMU @hornung_lab @khmelinskaia @LFMilles @SchwilleLab @RaedlerLab @BenediktSabass

[Jacob Corn @jcornlab]

Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in @NatureBiotech for the story & ways to improve HDR. https://t.co/03GokR65LA With @karasuerman1 & @J_Maciejowski

[The Langer Lab @langer_lab]

🥳🚨Paper Alert🚨🥳
Excited to present our latest work on #Opa1 in this newly published paper @ScienceAdvances by @sahola6 and @LPazurek. We present here two new mouse models with impaired Opa1 processing. 1/🧵
https://t.co/88eaOnzeO1
#mitochondria #mitochondrialdynamics @MPIAGE

[Jae Lab @TheJaeLab]

Don’t miss this great opportunity! Deadline is September 13.

[QMB Munich @MunichQbm]

🚀Wanna do your PhD at QMB? Apply NOW!
Engage in interdisciplinary research that integrates experimental and theoretical approaches, or focus solely on theoretical work, and become a leader in the emerging field of quantitative, systems-oriented bioscience.https://t.co/af3syVPeiD

[Gene Center Munich @GeneCenter_LMU]

🚀Our celebratory symposium last Monday was enjoyed by all participants😀😆. Bavarian Minister of State Blume and LMU President Huber offered their congratulations. Patrick Cramer, President of the Max Planck Society, sent his greetings via video message.

[Alexander Bartelt @BarteltLab]

There is a new study section @GBM_eV @JuniorGBM on Organelle Biology and I have just joined - exciting initiative by @winklhofer_lab & @Herrmann_lab and very relevant for our new @dfg_public Priority Program

[Jae Lab @TheJaeLab]

@ThijnBrummel Congrats, Thijn! Powerful stuff! #HaploidGenetics

[Veit Hornung @v_hornung]

Excited to share our latest study in @ImmunityCP showing how PLD exonucleases together with RNase T2 process RNA upstream of TLR7. ✂️🧬

Kudos to @BeroutiMarleen for her fantastic work!

https://t.co/nXXoCEcgmJ

[Mikko Taipale @mike_tilapia]

Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ https://t.co/vzNbJyR2rk https://t.co/5S9i7UG7JL

[@luschnig.bsky.social @StefanLuschnig]

Looking for a postdoc position to study epithelial tissue dynamics in Drosophila? New institute, interdisciplinary, international environment and very livable place @uni_muenster
One week left to apply, see https://t.co/esjOrXhFiJ

[Pavel Kielkowski @pavelkielkowski]

Let's do the right click! In chemical proteomics chemoselectivity of the CuAAC is crucial. Andreas Wiest in our group found that formation of the ubiquitous thiotriazole byproduct during the click reactions can be easily diminished: https://t.co/5uKlRx3n6i. Congratulations!

[Gene Center Munich @GeneCenter_LMU]

📣📣📣Great opportunity for ambitious junior researchers🫵
We are looking for an Independent Group Leader in Nucleic Acid Research🧬
https://t.co/fLEO8qyrFR
Please RT🙏
#ApplyNow #Career