Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8+ TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 https://t.co/wiKVvR4Ldz
Congratulations @simpak, @susanna_c_, & @LMackayLab! An exciting story and an epic effort by three of the hardest-working, talented scientists you could hope to work with!
🌟Excited to share our latest work on how functionally distinct skin TRM utilise different pathways to establish residency, published today in @ScienceMagazine! A true labour of love by BFF @simpak and @susanna_c_! 👩🔬 @TheDohertyInst@UniMelb @UniMelbMDHS https://t.co/3m3tNsKqUe
Honoured to be awarded the @AAMRI_Aus@CSL Rising Star Award 💫 So grateful for the recognition of our work to unravel tissue immunity 🔬🎉
@TheDohertyInst@Unimelb
In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance?
Read to find out! In our new work from the @EJohnWherry lab, out now at @SciImmunology, we...
https://t.co/fHISKaFcZm
Our latest work is out @ImmunityCP ! Find out how we used surface proteome analyses to explore circulating and tissue-resident memory T cells diversity across tissues & many more!👇
https://t.co/KKpzzFjdnS
@LMackayLab@TheDohertyInst#teamTRM 🧪🔬🧵
🚨 New paper alert out now in @PNASNews! Have you ever wondered how T cells search the host for antigen in animals that don’t have lymph nodes (ie fish, amphibians, birds, reptiles)? Then this one’s for you: https://t.co/lBliv3T2Tv
@ZebrafishRock@LabHutt#Immunology#zebrafish
Gearing up to offer our DIYtranscriptomics course again this Spring semester (Jan), covering bulk and #singlecell RNA-seq. All video lectures will be freely available online. Updated labs too! Something specific you'd like to see? Post in the comments!
https://t.co/iDxjDdiaIY
We are happy to share our latest publication from Mary Margaret Addison, PhD! Here, she highlights the ability of activated CD4+ T cells to act as antigen-presenting cells and present endogenous antigen derived from infectious HIV-1! https://t.co/4RLCL8ATYr
@Youngthepro@LMackayLab@NatImmunol@raissaf@TheDohertyInst Interesting question! Given ThPOK and RUNX1 can repress RUNX3 expression (at least during T cell development), we might predict that overexpression of either factor would inhibit epithelial CD8 TRM formation.
Have you ever wondered what controls tissue residency in CD8 vs CD4 T cells? Find out today! @NatImmunol https://t.co/wR4MpECRbU 🧵👇 Amazing teamwork @raissaf@TomBurn8@TheDohertyInst 🧑🔬
Excited to see our new study out in @JExpMed ! Find out how S1PR5 regulates T cell migration and their differentiation into resident-memory T cells here 👇 https://t.co/ik0eBWyujh
Thank you @LMackayLab, our amazing #teamTRM@TheDohertyInst and all co-authors!