Tom Thomas

Drug Development | MD DPhil (Ox) | Ex-VC Fellow @ArtisVentures

[Calli Dendrou @CalliDendrou]

Why do some inflammatory bowel disease patients benefit from anti-TNF therapy whilst others do not?

Our new @NatImmunol resource paper investigates this question by following patients before and after treatment: https://t.co/AmOpIBwqjB 👇

[Tom Thomas @TomThomas3000]

@danielt_illborn Phenomenal piece of work - masterclass in world building and character development

[Mark Dawson @MAF_Dawson]

The career question I get asked the most is “why did I become a Physician-Scientist” - too often I give a vanilla answer to this - some colleagues have a Eureka moment- for me it was uncertainty, failure & extraordinary mentorship that set me on my journey https://t.co/RpTHgDuwCM

[The Pharmaceutical Journal @PJOnline_News]

NICE says genetic testing before initiating clopidogrel is a cost-effective use of NHS resources for patients at risk of stroke

https://t.co/hsiOOkyaq6

[Zhijuan Qiu @Zhijuan_JExpMed]

Today's #JEMLegacy @JExpMed highlights the work of Fiona Powrie @powrie_lab & colleagues showing #Treg cells constitutively express #CTLA-4 and signaling via CTLA-4 is essential for their function to control intestinal inflammation. https://t.co/QgHHi2ntnh

[Tom Thomas @TomThomas3000]

@1RabP Thank you for your kind words!

[Nirantharakumar @Nirantharakumar]

Proud to be part of Dexter, as a tool for clinical trials. Dexter can help with quality improvement, predictive analytics and informatics consult in addition to observational studies and clinical trials. @KrishnaGokhale @UoB_IAHR @HDR_UK @JohtChandan

[Heather J Faust @HeatherJFaust]

Please check out my paper on healthy synovial fibroblasts and the role of cortisol signaling, now on Bioarchive. Much thanks to all my co-authors!! @ilyakorsunsky
@lynchielydia @AHelenaJonsson1 @FanZhang_Jessie @soumya_boston https://t.co/hjVYwMv3fq

[Rockefeller U. Press @RockUPress]

Do T cells remember what we eat? In @JExpMed, Lockhart, @danmucida et al @RockefellerUniv show that physiological exposure to food protein drives CD4+ T cell accumulation, clonal selection, and transcriptional adaptation at the intestinal epithelium. https://t.co/sdf4474qNB

[Dr. Fan Zhang ⛵️ @FanZhang_Jessie]

Excited to share another Bioinformatician position in our lab based on our recent fundings!! Great opportunity to develop computational AI methods for longitudinal #SingleCell omics for translational medicine! https://t.co/20Lx1ltNCG @CUBiomedInfo @CURheumatology DM me directly🙌

[Mark Lawrence @Mark__Lawrence]

To celebrate the release of THE BOOK THAT WOULDN'T BURN...

...everyone who retweets this g̷e̷t̷s̷ ̷a̷ ̷c̷a̷r̷ ... I mean is in the draw for a signed, dedicated copy ... I'll even number it for you!

[Tom Thomas @TomThomas3000]

Similar scale work needed in the Indian subcontinent as well given rising incidence rates!

[Sang Hyoung Park, MD, PhD, AGAF @sang_hyoung]

Congrats on this groundbreaking work!!! @BDYE_IBD #HosuLee #KyuyoungSong @doc_ibd @JudyCho7 @AsanIbd @NatureGenet https://t.co/OBuOgeMc3l

[Jason Sheltzer @JSheltzer]

Fascinating new preprint on bioRxiv tackles a whale of a question:

Whales are huge. So why don’t they get a ton of cancers?

https://t.co/z0KjxPUebi

[Arno Bourgonje @BourgonjeArno]

Very happy to announce that today two papers on #PhIPSeq in (1) the general population (🧵 by @sea_andreu) and (2) in patients with inflammatory bowel diseases (#IBD), got published today in @ImmunityCP https://t.co/N1VhJNijEJ
https://t.co/8wCMV3YeEp 🧵 on IBD findings:

[Tom Thomas @TomThomas3000]

@FanZhang_Jessie Thank you so much for your advice and input @FanZhang_Jessie - much appreciated!

[Yavuz Yazicioglu @YavuzYaziciogl1]

Delighted to share our paper on mitochondrial dynamics in B cells and lymphoma. Really grateful to my supervisor @a_j_clarke for his invaluable support and mentorship. Huge thanks to my co-supervisor @MichaelLDustin, collaborators and colleagues @KirOxford & @UniofOxford

[Journal of Experimental Medicine @JExpMed]

#Macrophages in the synovial lining niche initiate #neutrophil recruitment and articular #inflammation, say Kristina Zec, Irina Udalova et al. @UdalovaLab @KirOxford https://t.co/AFs5VUMtxr
#arthritis

[Tom Thomas @TomThomas3000]

https://t.co/Gzvt36nHb9

[Cameron McAlpine @cam_phd]

We are thrilled to share the first publication from the McAlpine lab! Out today in @ImmunityCP.

“Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis”

@IcahnMountSinai @SinaiHeartBlood @SinaiBrain

https://t.co/WlWY1fFRa9