LaMoia and Shulman @YaleMed tackle the fascinating, sometimes contentious topic of metformin action #T2D#EndocrineReveiws Great figures, open access! @TheEndoSociety https://t.co/Mupubc3JgN
New! Online now: Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo https://t.co/eFZVuAAUb8
COMMENT | Glucose clamps are challenging to conduct in mice & experimental approaches vary between labs, complicating data interpretation. Ayala et al. (@VanderbiltU) highlight methodological differences & propose reporting standards. #glucose#tbt 🔙
https://t.co/gxels1b4Hf
We published the 1st sk.muscle specific AKT KO in 2019 (PMID: 31444134), which showed AKT signaling is dispensable for insulin stim. glucose uptake in adult muscle. Reassuring to see these results now confirmed by the Kadowaki group @NatureComms@MolMetab
https://t.co/V0JE4I9gqI
Fascinating: lactate sensor shows that mitochondrial lactate pools are ~5x bigger than nucleo-cytosolic pools https://t.co/kFTU15c8qg; are there implications for our reliance on whole cell pyr/lac as readout of cytosolic NAD/NADH?
Very proud to see our latest story and my art work in the cover of @Cell_Metabolism picturing the damaged, leaky #mitochondria due to oxidative stress and #ferroptosis
https://t.co/uugGxUNXYU
Interested in #mitochondria, #metabolism, and/or #heartdisease? Want to work in NYC right by Central Park? We're looking for postdocs, technicians and graduates students! @SiniaHeartBlood @IcahnMountSinai@mitojobs
DM or email for details. Please RT!
https://t.co/1BvrNHz1td