Online now: Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies https://t.co/PRKQ1azpFV
Happy to share our recent work on spatially distinct Neutrophil functions in gut inflammation. Congratulations to @LenoreYalom on her well defended PhD thesis work and a beautiful paper that came out of it. https://t.co/PHAdIptnsq
#SharingIsCaring… or not? Togashi, Ikeda &co show @Nature that #tumor cells transfer poisoned #mitochondria resistant to #mitophagy to tumor-infiltrating lymphocytes. Tumor mtDNA with mutations drives senescence & deficient effector & memory functions! https://t.co/dBlGjbOaDJ
Possibly my last co-first author paper in academia: Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma. Enjoyed the collaboration at Dana Farber! https://t.co/ESnRQEQRan
Review @SciImmunology@viditbhandarkar@stefanispranger
DC–T cell interactions during priming influence CD8+ T cell fate, and DCs subsequently sustain T cell responses against cancer
https://t.co/CoMnWn1WiC
Online now: Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion https://t.co/fnnRUAvbBg
This is such an unacceptable response for an NIH PD to give to a trainee. For the record she did read the notices and discuss with her mentor (me), and I recommended she reach out and ask. Wonder why talented young people are leaving academia? This is why @NIH 😑
ICYMI: Macrophages that were exposed to dying cells in vitro, induced different gene expression programs in response to IL-4 depending on the identity of apoptotic cells they had engulfed. This suggests macrophages are what they eat! #Immunology
https://t.co/MIhqC3sLfF