Tilman

Computational geneticist interested in complex traits and untangling the underlying genetic mess.
PhD student with @OrjanGenetiker at @UU_University

[Örjan Carlborg @OrjanGenetiker]

The project where we "did it all": sequenced the genomes of every available individual (>3,300) from 18 generations. Result? Increased power facilitating mapping of 40 loci for the single analysed trait at 10% FDR (12 reached a 5% genome-wide threshold). @yanjunzan @Troe2710

[Tilman @Troe2710]

@nr_claudio @MalwadeSusmita

[Örjan Carlborg @OrjanGenetiker]

Our latest work on public yeast data exploring GxGxE interactions. Environmental changes often modulated the i) connectivity in epistatic networks, and ii) level of genetic capacitation. Interesting mechanism where segregating genetic variants only acts in specific conditions!

[Örjan Carlborg @OrjanGenetiker]

Will be recruiting two computational genetics PhD students for fall 2019. Projects include both methods development and experimental data analyses. Focus is on polygenic complex traits, adaptation, epistasis and G-by-E interactions. PIs: please forward to suitable candidates/RT

[Örjan Carlborg @OrjanGenetiker]

We had a large population & little money for genotyping. This is how we solved it & I’m really happy with the results. Hope the approach, detailed protocol & software will be of use for someone else too! Work w @yanjunzan @ThibautPayen @MetteLillie et al