VaD Matrix

Consortium of researchers from Edinburgh, Glasgow, Manchester, Oxford & Cambridge investigating #extracellularmatrix defects in #SVD #dementia #stroke

[VaD Matrix @VaD_Matrix]

Our consortium is ecstatic to announce the launch of our website! Visit us at https://t.co/SfF7Ou5GXj to find out all about our research on #NeuroGlioVascularUnit #MatrixBiology in #stroke & #dementia & the faces behind it @TheBHF @TheStrokeAssoc @alzheimerssoc @ARUKnews @BSMB1

[VaD Matrix @VaD_Matrix]

@SelinaWray Couldn’t agree more. Disgraceful treatment of the future of UK science.

[VaD Matrix @VaD_Matrix]

Sorry to hear this Emily. Sadly, despite huge efforts by many to change things, such views are ingrained in many academics. We can only hope it will change sooner rather than later.

[Emily Sena @profEmilySena]

Reviewer/panel comments to another rejected grant.
Main theme was ”applicant has co-authored ~79 academic articles, >9,380 citations, h-index of 41.
Only weaknesses is no stellar papers in top-tier journals”. How is this still legit?! #ImpactFactor #sfDORA #tired

[Alex Granata @DrAlexGranata]

Very well done to my student Mary for winning the best poster prize at the #cambridgeneurosciences departmental AWAYDAY!!! 👏👏👏👏👏🎉🎉🎉🎉@CamStroke @Cambridge_Uni @Cambridgecardio @VaD_Matrix

[VaD Matrix @VaD_Matrix]

Fantastic! Great to see our programme research findings presented 😊 stay tuned for more data on Col4a1 contribution to #SVD @CamStroke @TomVanAgtmael

[Cambridge Stroke @CamStroke]

Our article just out. How common are single gene mutations as a cause for lacunar stroke? Answered using sequencing panel. Funded by @TheBHF and NIHR @StrokeGenetics @CamNeuro @Cambridgecardio https://t.co/XavGHw1xFo

[VaD Matrix @VaD_Matrix]

Fantastic meeting yesterday with all of our consortium collaborators. Lots of exiting data from @Horsburgh_Lab @CamStroke @CaderLab @DrAlexGranata lab 🧪 🔬 and more! And now let’s get those papers out! It’s going to be a very prolific 2020! Stay tuned! #stroke #vasculardementia

[Cambridge Stroke @CamStroke]

Another great meeting of ⁦@VaD_Matrix⁩ fighting vascular dementia ⁦@TheStrokeAssoc⁩ ⁦@Cambridgecardio⁩ ⁦@alzheimerssoc⁩ ⁦@TheBHF⁩

[Cambridge Stroke @CamStroke]

Another great meeting of ⁦@VaD_Matrix⁩ fighting vascular dementia ⁦@TheStrokeAssoc⁩ ⁦@Cambridgecardio⁩ ⁦@alzheimerssoc⁩ ⁦@TheBHF⁩

[Work Research group @teamWorkstroke]

We are so excited to be involved in the LOC planning for this meeting 🙌🏴󠁧󠁢󠁳󠁣󠁴󠁿🧠 along with @JosieNeuro @stu_art_here @Horsburgh_Lab @Fowler_JH @EdNiBL @alysonmiller24 @neuronerdsunite @Maclomaclee @JaimeCPI @ConferencePart @meetglasgow + several others not in Twitter!

[Cambridge Stroke @CamStroke]

Interesting study suggesting #AD and vascular pathology’s have differing effects on #brainnetworks - but what influence does vascular disease have on the BOLD response underlying the networks? We found functional networks had poor reproducibility in #SVD https://t.co/DK2pGe4PAe

[VaD Matrix @VaD_Matrix]

Some of the amazing work from our programme on #CollagenIV #dementia and #stroke using #iPSCs Well done Mary!👏🏻

[Alex Granata @DrAlexGranata]

Perfect poster picture of my student Mary presenting her work on iPSC-BBB model of collagen IV SVD at the 22nd International Symposium on Signal Transduction at the Blood-Brain Barrier in Wurzburg @CamStroke @VaD_Matrix

[Alex Granata @DrAlexGranata]

Perfect poster picture of my student Mary presenting her work on iPSC-BBB model of collagen IV SVD at the 22nd International Symposium on Signal Transduction at the Blood-Brain Barrier in Wurzburg @CamStroke @VaD_Matrix

[Alex Granata @DrAlexGranata]

If you are interested in stem cell disease modelling, mechanisms of atherosclerosis & inflammation in stroke and epigenetics, this is the job for you👇 Spread the word! @CamStroke @Cambridgecardio @SanjaySinhaUK

[Cambridge Stroke @CamStroke]

Stroke is a syndrome not a single disease and determining the cause is important in guiding treatment. A practical guide to diagnosis and its effect on treatment here. Personalising secondary prevention: different treatments for different strokes https://t.co/BQk7q0UlNq

[VaD Matrix @VaD_Matrix]

Check out the latest review on #basement membranes and #collagen co-authored by two of our programme researchers @TomVanAgtmael and @Gaia_Brezzo

[Tom Van Agtmael @TomVanAgtmael]

Excellent job by @AnnaGatseva @Gaia_Brezzo and Yuan Yan (Angie) Sin (but I am biased!).... Review article: Basement membrane collagens and disease mechanisms #Essaysinbiochemistry @PPPublishing. @UofGICAMS https://t.co/sHQ9W7V9Ae.

[Alex Granata @DrAlexGranata]

We are seeking an enthusiastic and experienced postdoc to work with us on very cool project, looking at the mechanisms of atherosclerosis/inflammation driven by HDAC9 in large-vessel stroke using stem cells. Spread the word! https://t.co/rKguYg3WlC @CamStroke @Cambridgecardio

[VaD Matrix @VaD_Matrix]

Will be interesting to see if #NOTCH3 is also implicated in other Col4a1 mutations @Horsburgh_Lab @TomVanAgtmael

[Cambridge Stroke @CamStroke]

Exciting data showing importance of SMC loss in ICH in COL4A1 and that this is modulated by NOTCH 3 pathway - might explain why ICH less common in CADASIL despite SMC loss ⁦@VaD_Matrix⁩ ⁦@StrokeGenetics⁩ ⁦@Cambridgecardio⁩ ⁦@Cadasilsupport1⁩

[VaD Matrix @VaD_Matrix]

#ESOC2019 goers! Make sure to chat to Gaia about a novel mouse model of SVD. This is novel research from our #vascular extracellular matrix consortium.

[VaD Matrix @VaD_Matrix]

Job adverts here; https://t.co/1E1BPxFbrU. https://t.co/97jkWqXt9o

[VaD Matrix @VaD_Matrix]

Amazing to see such great science at #ARUKconf! Stop by poster 11.2 & chat to @Gaia_Brezzo about novel mouse model of #SVD. If you are drawn in, we are recruiting in Manchester & Cambridge! If you have experience in #iPSCs we want to hear from you! @stu_art_here @DrAlexGranata