Vedran Vasic

Protein biochemist and molecular biologist. Views and opinions are my own.

[NASA Webb Telescope @NASAWebb]

👀 Sneak a peek at the deepest & sharpest infrared image of the early universe ever taken — all in a day’s work for the Webb telescope. (Literally, capturing it took less than a day!) This is Webb’s first image released as we begin to #UnfoldTheUniverse: https://t.co/tlougFWg8B

[Vedran Vasic @VedranVasic]

@isaac_fianu @ScienceMagazine @CramerLab Wow, Isaac! Congratulations!

[Cell @CellCellPress]

New review covering the #hallmarks of #health, now online! https://t.co/57n7LCn0h7

[Vedran Vasic @VedranVasic]

@CramerLab @hauke_hillen @uniGoettingen @mpi_bpc Congrats Hauke! Well deserved!

[Vedran Vasic @VedranVasic]

Our new paper on the ERAD E3 ubiquitin ligase Doa10 is out in @eLife! Congratulations to @clautinaschmidt and the Stein lab @mpi_bpc!

[Claudia Schmidt @clautinaschmidt]

Check out our latest paper from the Stein lab (@mpi_bpc, @VedranVasic ) where we provide molecular insights into the endoplasmic reticulum ubiquitin ligase Doa10!
Using a fully reconstituted system, we show that it is a membrane protein retrotranslocase.

https://t.co/v4x8vcTIh4

[Vedran Vasic @VedranVasic]

@CramerLab Congrats @isaac_fianu :)

[Kashish Singh @kash1shsingh]

Cryo-EM structure at 1.25 angstrom from the Stark lab @mpi_bpc. #CryoEM

https://t.co/Y64ro9Dspu

[Rebecca Voorhees @voorheeslab]

A brief COVID respite:
Structure of the human ER membrane protein complex. https://t.co/g0cyL1Hp7E

A glimpse into the role of this crazy complex in membrane protein biosynthesis.

Congratulations @TinoPleiner, Gio, Kurt, @aj_inglis, and Masami. @Caltech

[Vienna Biocenter Ubiquitin Club @VBC_Ubiquitin]

Please RT! Registration is now open for the 7th Ubiquitin&Friends Symposium, which will be on 14-15 May in Vienna https://t.co/DcThJWHKa7 Amazing lineup, great location, and most importantly friendly atmosphere. Hope you can join us!!!

[Patrick Cramer @mpgpresident]

Here is a simple animation of #coronavirus replication:
NTPs enter from the right and are added to the growing RNA copy (red) of the #SARSCoV2 RNA genome (blue) by the viral polymerase. #COVID19
Preprint: https://t.co/KWD2bgPWGb
Press release: https://t.co/bT7ig1Oyjc

[Cell @CellCellPress]

In the latest issue: on-demand secretion of #inflammatory factors and protein cargoes lacking #secretion #signal sequences relies on #TMED10, a protein that oligomerizes to channel the cargoes into secretory #vesicles https://t.co/wEWByNbKwj

[Cell @CellCellPress]

Now @CellCellpress - Human recombinant soluble #ACE2 (hrsACE2) reduces #SARSCoV2 viral load, suggesting #hrsACE2 can block early stage infection https://t.co/pHi0swPf2W
For @CellPressNews #coronavirus research- https://t.co/BCdU2ltXnp
#COVID19

[Patrick Cramer @mpgpresident]

Watching #coronavirus replication!

#SARSCoV2 polymerase-RNA structure: basis to study potential #COVID19 drug #Remdesivir

Team @hauke_hillen @KokicGoran @LucasFarnung @c_dienemann @DTegunov @mpi_bpc @maxplanckpress

Preprint https://t.co/KWD2bgPWGb

PR https://t.co/bT7ig1Oyjc

[Vedran Vasic @VedranVasic]

A truly remarkable paper. Congrats to the Rapoport lab and everyone involved! Having personally spent the past five years eating, sleeping and dreaming about the Hrd1 complex, I'm fascinated to finally see it in its full glory.

[Rapoport Lab @RapoportLab]

Congratulations to Xudong Wu on the publication his new paper today in @ScienceMagazine! This is the culmination of years of work to solve the structure of th ERAD-L retrotranslocation complex.

https://t.co/XHB78TLlTd

[Vedran Vasic @VedranVasic]

@RapoportLab @ScienceMagazine Congratulations Xudong and colleagues! This is truly incredible work!

[Vedran Vasic @VedranVasic]

High resolution CryoEM structures show a new regulatory subunit of yeast fatty acid synthase (FAS), structurally similar to mycobacteria FAS. Has potential for new tuberculosis therapeutics. Congrats to the Chari/Stark and Tittmann groups! @mpi_bpc https://t.co/rJ6EcJ6dIM

[Vedran Vasic @VedranVasic]

Saying the words “stay healthy” emitted thousands of saliva droplets. A cloth mask reduced droplet emission down to background levels. #Coronavirus Could SARS-CoV-2 be transmitted via speech droplets? | medRxiv https://t.co/bEyXWxffuC

[Ivan Đikić @iDikic2]

Congratulations to Donghyuk on the first crystals of CoV2 protease. Such a good feeling and highly promising. #Science can deliver a lot in a short time when a small group of scientists (#CoV team) works closely together (most of the lab is shut down). 🙌😀👏👨‍👩‍👦‍👦

[Vedran Vasic @VedranVasic]

@AgataWitkowska @SandoghdarLab @mpi_bpc @MPI_Light @uniGoettingen @thegoecampus @MPZ_PhysMed Congrats Agata!

[Vedran Vasic @VedranVasic]

An interesting pre-print by the @TobiWalther lab. Used SILAC to assay global protein stability and identified new physiological substrates of ERAD. #ubiquitin #proteomics #proteinqualitycontrol https://t.co/KKS4aYKvDC