Wonjo Jang

Neurology resident at Mass General Brigham/Harvard Medical School | Lambert lab | GPCRs, Neurobiology, BTS

[Wonjo Jang @WonjoJang]

Does endogenous heterotrimeric G proteins trafficking rely on acyl cycling as much as monomeric G proteins do? Check out new Lambert paper! https://t.co/IAeztqCw2I

[Cell @CellCellPress]

In the latest issue! Direct interrogation of context-dependent GPCR activity with a universal biosensor platform https://t.co/fDuMZiSef2

[Makaía Papasergi-Scott @MPapasergiScott]

Very happy to have my recent work on "Time-resolved cryo-EM of G protein activation by a GPCR" out in Nature today! #cryoEM #GPCR @Nature #LabSkiniotis https://t.co/rrL5zPfXRK

[Wonjo Jang @WonjoJang]

Special thanks to all the Lambert lab members who made this project possible!

[Wonjo Jang @WonjoJang]

Excited to share a new preprint by Lambert lab! https://t.co/8wu0A95fU1
While GPCR signaling from intracellular compartments have been well studied, it is unclear how G proteins are supplied to them. (1/n)

[Wonjo Jang @WonjoJang]

Our subcellular map of endogenous G protein distribution suggest that G proteins may be partially excluded from nascent endocytic vesicles, and are likely to have implications for GPCR signaling from endosomes and other intracellular compartments. (n/n)

[Mikel Garcia-Marcos Laboratory @MGMlab]

Do have an interest in #GPCR signaling? Did you always want a good assay that worked in your favorite cell type? Even with endogenous GPCRs? This might be for you. We got some surprises about endogenous GPCR behavior. Remi + Marcin led, with help from many https://t.co/H50CuWJTy8

[Mikel Garcia-Marcos Laboratory @MGMlab]

We found a new twist on how #GPCR signaling is regulated to tweak neurotransmission. Biased signaling? Maybe. But somewhat different from the usual.

JC + Alex —> biggest push.
Thanks to @KLabGPCR and Yano lab for joining this loooong journey.
Free link: https://t.co/NUxWQKPoRp

[やし @AlHSJCKtEfpFXtm]

https://t.co/2njGn27ham
We are so thrilled to share our latest research!
We revealed a new and intriguing GPCR activation mechanism from the intracellular agonist.

[Structure @Structure_CP]

Team headed by Gregory Tall & Georgios Skiniotis @StanfordMed presents the cryo-EM structures of Ric-8B with with Gα protein folding clients Gaolf and Gas

https://t.co/Tp3V9A6vFb

[Ben Myers Lab @Myers_lab]

Excited to present a new story focusing on how the #GPCR #SMOOTHENED activates GLI transcription factors in the primary cilium during #Hedgehog signaling! Fantastic collab with Radhika Subramanian, @GeXuecai , and many others.

https://t.co/vktp4hZatt

[Makaía Papasergi-Scott @MPapasergiScott]

📰Check out our latest work from @LabSkiniotis on "Time-resolved cryo-EM of G protein activation by a GPCR" that is now on @biorxivpreprint!👀 #GPCR #cryoEM [a thread w/ videos below] (1/6)
https://t.co/RwJGD5BqbQ

[Makaía Papasergi-Scott @MPapasergiScott]

Super excited to share our recent collaborative work between @LabSkiniotis and @lab_tall showing structures of Ric-8B complexed with Gαs and Gαolf https://t.co/mKaoQP3TLK

[Tall G protein Lab @lab_tall]

The Ric-8B G alpha s/olf structures are the first of any pose for G alpha olf and the hard work of @MPapasergiScott, Frank Kwarcinski, @maiya_yu, Ouliana Panova, Ann Ovrutsky in a fun collaboration with @LabSkiniotis

[Wonjo Jang @WonjoJang]

@PhRMAfoundation @MCG_AUG @nchembio Thank you for the highlight!

[Wonjo Jang @WonjoJang]

@Myers_lab Thank you for the shout out!

[Wonjo Jang @WonjoJang]

@katprichardson Thank you! 😀