X David Li Lab

Professor in HKU Department of Chemistry，School of Biological Science and School of Biomedical Science. Epigenetics and Chemical Biology.

[X David Li Lab @XDavidLiLab1]

@LilingWanLab @nchembio Thank you, Liling!

[X David Li Lab @XDavidLiLab1]

We have reported a series of first-in-class inhibitors for YEATS domain proteins since 2018, including an ENL inhibitor in 2018, an AF9 inhibitor in 2020, and now the first YEATS2 inhibitor. This work is now published in @nchembio
https://t.co/QmwlzeFoim

[X David Li Lab @XDavidLiLab1]

Tenure-Track Professoriate Position in Chemical Biology at The University of Hong Kong
https://t.co/uaR8EkacWj

[X David Li Lab @XDavidLiLab1]

@doc_jlmeier Oh, I miss this place! Last time being there was 2019.......

[X David Li Lab @XDavidLiLab1]

Congrats to Shixian @Linlab_ZJU on this paradigm-shiftimg work. Unnatural amino acid incorporation using rare codons. Really COOL!!

[Shixian Lin @Linlab_ZJU]

🔊Check out our work in @ScienceMagazine. We identify a new weak point (TCG codon) in the codon table of mammalian cells and recode it into non-canonical amino acids (ncAAs) with impressive efficiency and selectivity. This strategy, rare codon recoding (RCR), is very different!

[X David Li Lab @XDavidLiLab1]

A new application of photo-ANA to interrogate tissue-specific protein-protein interactions is now published in PNAS.

MACSPI enables tissue-selective proteomic and interactomic analyses in multicellular organisms | PNAS https://t.co/I6TxeyD4vY

[X David Li Lab @XDavidLiLab1]

How long and how much it takes from idea to publication?

Here is my tale of three molecules that I designed more than 11 years ago.

[X David Li Lab @XDavidLiLab1]

I am honored to receive this recognition from HKU, where I studied and have served for more than 12 years😊

[The University of Hong Kong @HKUniversity]

Congrats to Prof David Li (@XDavidLiLab1) from @HKU_Chemistry and Prof Stephanie Ma (@stephaniema912) from @hkusbms on being awarded this year's #HKU Outstanding Researcher Award for their exceptional research accomplishments!

🎥https://t.co/FlAgtzz7f3

[X David Li Lab @XDavidLiLab1]

@_chrisgparker_ @ChemicalBiology @ForliLab @bmsnews Awesome work!! Congratulations!🎉🎉🎉

[X David Li Lab @XDavidLiLab1]

A Must-Read thoughtful and comprehensive review from my colleague Xuechen @LiXuechen_HKU, a Master of Chemical Protein Synthesis!!

[Xuechen Li @LiXuechen_HKU]

We put a lot of thinkings and efforts in this paper. Hope this will be useful to the peptide/protein chemistry community. "Precision in Protein Chemical Modification and Total Synthesis". https://t.co/2h0vwcNjcW

[X David Li Lab @XDavidLiLab1]

Reunion of Kapoor lab @KapoorLab_RU alumni @JeffTiLab @XDavidLiLab1 and collaborator @Hippo326 for hotpot in Hong Kong😁

[X David Li Lab @XDavidLiLab1]

Great to visit @TheCrick institute for the first HKU-Crick symposium together with many colleagues from @hkusbms @hkumed @hku_science. As the only chemist in the symposium, I am glad to learn lots of new frontier biology.

[Max Gutierrez @maxgabgut]

Great to meet so many people from @hkumed @hkusbms - thanks for coming to visit @TheCrick

[X David Li Lab @XDavidLiLab1]

@LiXuechen_HKU Wow👍

[X David Li Lab @XDavidLiLab1]

@Rongsheng_Wang @TetrahedronChem @hku_science @HKU_Chemistry Thank you, Ross!

[X David Li Lab @XDavidLiLab1]

I am very honored to receive 2024 Tetrahedron Young Investigator Award for Bioorganic and Medicinal Chemistry.
https://t.co/rO3GTSwolk
Thanks to @TetrahedronChem for recognizing our works, and continuous support from @hku_science and @HKU_Chemistry

[X David Li Lab @XDavidLiLab1]

@AlanZeXiong @TetrahedronChem @hku_science @HKU_Chemistry Thanks, Ze.

[X David Li Lab @XDavidLiLab1]

@iUmyrr @TetrahedronChem @hku_science @HKU_Chemistry Thank you!

[X David Li Lab @XDavidLiLab1]

@JeffTiLab @TetrahedronChem @hku_science @HKU_Chemistry Thanks, Jeff!

[X David Li Lab @XDavidLiLab1]

@InLiuOfBulkExps @TetrahedronChem @hku_science @HKU_Chemistry Thank you, Shixin!

[X David Li Lab @XDavidLiLab1]

@JianHe_HKU @TetrahedronChem @hku_science @HKU_Chemistry Thanks, Jian

[X David Li Lab @XDavidLiLab1]

@XuhuiHuangChem @TetrahedronChem @hku_science @HKU_Chemistry Thank you, Xuhui!