Yin Loon Lee

Cell biologist from 🇸🇬 @astar_research, co-founder at Nuevocor, postdoc @LabBurke, PhD @StearnsLab. Nuclear mechanotransduction, #microtubules, #RareDisease.

[Yin Loon Lee @YLLee_CellBio]

My first paper as a co-corresponding author has been accepted @hmg_journal. A long-running team effort with co-first authors Ei Leen and Thet, @cadotbru and other authors, my thanks to @LabBurke and Colin Stewart for letting me drive this.
https://t.co/vVWuPvegQr?

[Andrew Holle @ahcells]

#Preprint alert! Check out @ConfinementLab’s new research on the role of #mechanical #memory in potentiating confined migration: https://t.co/6oNLRhsYMl

[Mechanobiology Institute @MBIsg]

Day 1, done and dusted! But the party is just getting started with The Hawker Center Mentorship Night at three of Singapore’s most iconic hawker centers – ABC Brickworks, Lau Pa Sat and Newton Food Center. See you there! #MBIMPG2025

[Shailaja Seetharaman @shailajaseethar]

My lab @MBIsg and @NUSMedicine is recruiting a fully-funded postdoc to start in Jan 2026! Interested in cell and tissue mechanics, transcriptional regulation of tissue health, or AI/ML for disease mechanobiology? Come join us in Singapore!
https://t.co/qoZz02LPDY

[Lammerding Lab @LammerdingLab]

What allows lamins A and C to confer much stronger mechanical stability to the nuclei than lamin B? We show that even though all lamins can protect the nucleus from small cell intrinsic forces, only lamin A/C protect the nucleus from large deformations: https://t.co/wEkM2GXCZr…

[Jennifer Young @nano_jenn]

Interested in a #postdoc on cardiac #mechanobiology? Our lab has a fully funded position via our recently awarded @HFSP grant to study the biophysical processes that build insect hearts🪲🪰🫀

Come join us @MBIsg for some cool evo-devo-mechanobio work! 👇

https://t.co/BVOWW3ofLn

[Yin Loon Lee @YLLee_CellBio]

I am looking to hire a postdoctoral fellow to work on a collaborative project at the Mechanobiology Institute with the inimitable Sasha Bershadsky, focusing on interactions between the nucleus and the cell-ECM junctions in directed cell migration.

https://t.co/TpboD1iMaO

[Jennifer Young @nano_jenn]

Check out our lab's latest review by @MFarisHazwan @MBIsg @BME_NUS in Current Opinion in Cell Biology @sciencedirect

🔗https://t.co/e7UJmw6G3G

We teamed up w/Brian Aguado @ucsdbe to highlight region- & sex-specificity of #ECM signaling in the aging heart!🫀

Hope you enjoy!

[Andrew Holle @ahcells]

Interested in a #postdoc on nuclear #mechanobiology? We have a fully funded position in the @ConfinementLab designed to help you meet your career goals while researching the rapidly growing field of cellular #confinement. Please get in touch for more info!

[Mechanobiology Institute @MBIsg]

Our heartfelt condolences to Linda and all affected by this devastating news. Prof Michael Sheetz was an inspirational Founding Director of MBI and we would not be here today without his foresight and leadership. We hope to continue his legacy in mechanobiology for years to come.

[Andrew Holle @ahcells]

The @ConfinementLab's latest paper is out in @PNASNews! Fantastic work by @LY_Sci to build a tool to rapidly and accurately measure nuclear volume and surface area in #confinement. Thread below: https://t.co/NUXPQkz5p1

[Gautam Dey @Dey_Gautam]

Ok looks like we’re reaching critical mass on the other place! I won’t delete this account but I’ll stop actively posting - see you over there 💙

[Bomont Pascale @PascaleBomont]

👇SAVE the date 👇As the chair of the upcoming European meeting on Intermediate Filaments, I am happy to announce its launching. RT & more details to come. Thx organizing team with @BonneGisele @etiennemannevil A.Bertrand O.Agbulut #cytoskeleton @ConnectingIFs

[Prof. Michael Lin @MichaelLinLab]

This may be obvious to some but I'm now convinced: fierce competition for grants and papers is leading to low societal ROI (return on investment).

Why, when competition should mean only the best-formulated and executed work is accepted for funding and high-profile publication?

[Yin Loon Lee @YLLee_CellBio]

@BenjaminNanes @Dev_Cell Congratulations on the publication and making the cover!

[Benjamin Nanes @BenjaminNanes]

We’re thrilled to see our artistic rendition of the keratin intermediate filament cytoskeleton highlighted on the cover of @Dev_Cell along with our paper!
https://t.co/n5CjAyikSV

[Yin Loon Lee @YLLee_CellBio]

@SirioDupont @LammerdingLab @scita_lab @Ruprecht_Lab @LennonLab @PCusachs @KateMiro1 Glad to see our Sun1/2 DKO MEFs made it in. Will have to spend some time reading through your exciting new work!

[Sirio Dupont @SirioDupont]

🚨 Super psyched this story is finally out!

Herculean effort and 3rd chef d’oeuvre in @NatCellBio by @patriziaromani in just 5y, where we describe #mitochondrial #mechanotransduction.

https://t.co/l9oRSFdhaH

Megathread with bonuses ⬇︎⬇︎⬇︎

[Tim Stearns @StearnsLab]

Congrats to Ambros and Ruvkun! Read the original papers, which appeared together in 1993:

https://t.co/Pa7uzFw1H7
https://t.co/lSo9t5ez30

Back then, the finding that small RNAs - not protein - produced at one locus could control protein expression from another was big news!

[Jens Luders @LudersLab.bsky.social @LudersLab]

Happy to share (time-limited) free access to our latest work @Dev_Cell by Fabian Zimmermann @LudersLab @IRBBarcelona and @sernarina @CNIOStopCancer @LlorcaLab:
https://t.co/p88d1tAYQr
By reconstitution and #cryoEM we show how the #microtubule nucleator #gTuRC gets activated 🧵👇

[Prof. Michael Lin @MichaelLinLab]

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye!

The dye is tartrazine, used in Doritos!

https://t.co/fqVivyH0kI