Chelsea Powell

Current chemical biology postdoc fellow in @HMS_BCMP. Former therapeutics PhD student in Nathanael Gray's lab with @chemical_phd + @DFCI_ChemBio.

[Chelsea Powell @_CEPowell]

Congrats to Eddie and team!

[Edward Harvey, PhD @epharvey3]

Here we report the in silico discovery of functional MRGPRX2 antagonist nanobodies using AlphaFold2-Multimer. Thanks for the collaboration @katherine_susa @JSmithMDPhD

[Yingjia Chen @YChen2021]

Our paper is online now!!!! @StJudeResearch @postech2020 @ShanghaiTechUni Glut3 obstructs tumor immune surveillance by enhancing O-GlcNAcylation of cellular proteins in tumor-infiltrating Tregs.

https://t.co/vhxva4tB8M

[Milka Kostić, PhD @MilkaKostic]

One of my newest adventures - hosting a podcast!
If you are keen on chemical biology, medicinal chemistry, chemical probes, tool compounds, degraders, chemoproteomic tools, and more... tune to @Target2035 podcasts. Pilot episode is out... more to come!

https://t.co/1AHhUcJzap

[Radek Nowak @RPNowak]

We are hiring! Looking for a #postdoc to join the team in the Nowak Lab to focus on chemical biology in cells and recombinant systems. Excited about protein degradation, small molecule proximity? get in touch!
#TPD #InducedProximity #ChemicalBiology
https://t.co/SYxOT8RwCi

[Chelsea Powell @_CEPowell]

@bmart87 @LDI_ILD @McgillGBDO Congrats!!

[Yingjia Chen @YChen2021]

Excited to share that our work is online @cellhostmicrobe A small intestinal bile acid, taurodeoxycholic acid, is increased after sleeve gastrectomy and decreased in diabetic patients. It improves host metabolism by inhibiting the bacterial production of lithocholic acid.

[Hubert Huang @hai_tsang_huang]

Excited to share E3-substrate tagging by ubiquitin biotinylation (E-STUB) @nchembio! E-STUB enables CUL-RING ligase substrate identification and may transform the way we study glues and PROTACs by directly studying substrate ubiquitylation. 1/
https://t.co/et7SkRjds8

[Behnam Nabet @behnamnabet]

Are you interested in strategies to control the spatial localization of your favorite protein at will? In our review, @Saurav054 and I discuss the exciting development of chemical inducers of proximity to control subcellular protein localization. https://t.co/NXVpp0G4RF

[Chelsea Powell @_CEPowell]

@hojong_yoon Congratulations!!

[Chelsea Powell @_CEPowell]

Congratulations, Radek!! If you are looking for postdoc and tech positions please consider the Nowak Lab. Radek is an amazing person to work with!

[Radek Nowak @RPNowak]

NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! https://t.co/91TSBWYDTk

[Behnam Nabet @behnamnabet]

So proud to share my lab’s first PROTAC in @ChemBioChem #ChemBioTalents! In work led by @ErikoKoide & Kaela Mohardt, we developed a selective in vivo-compatible FAK inhibitor and PROTAC with exciting activity in pancreatic cancer models. A few highlights:

https://t.co/SKAgkHKJG0

[Megan McCurry @microbe_megan]

Pls circulate! If anyone is interested in doing a postdoc in how the gut microbiome modulates metabolic disease, look no further than Dr. Snehal Chaudhari’s new lab @UWBiochem. Snehal is a FANTASTIC scientist and mentor so I highly recommend checking out her lab ☺️

[Chelsea Powell @_CEPowell]

@microbe_megan Your choice 🦝 🦝

[Chelsea Powell @_CEPowell]

Amazing work, @ZHauseman!! Congrats!

[Zack Hauseman @ZHauseman]

I’m excited to share that my (official and formatted!) paper has been published in @Nature. The manuscript is centered around a high-resolution structure of a key protein complex for activation of the MAPK pathway- the MRAS-SHOC2-PP1C holophosphatase.

https://t.co/wgGDhHi1DR

[Chelsea Powell @_CEPowell]

@SamuelMLevi @Nature @AlisonWendlandt @CorinWagen @JacobsenLab @NIH_CommonFund @NSF @HarvardCCB @chemical_phd Congratulations, Sam!!

[Behnam Nabet @behnamnabet]

The Nabet lab @fredhutch is hiring! We are seeking a curious and highly motivated Research Technician to join our growing team and have exciting projects aimed at advancing new targeted protein degradation technologies. Please RT and apply here:
https://t.co/VQv28sv8LT

[Chelsea Powell @_CEPowell]

Our paper "Selective Macrocyclic Inhibitors of DYRK1A/B" is out now in @ACSMedChemLett. Great to work on this med chem story with John Hatcher and team @DFCI_ChemBio. https://t.co/mkl7osZY7C

[Chelsea Powell @_CEPowell]

@microbe_megan Yes

[Chelsea Powell @_CEPowell]

@miniboe Love it anyway! 🎶