Aarsh M. Dabhi

Forever Curious! #PhD Graduate Student at Centre for Molecular Neuroscience, KMC, Manipal • Ice - cream aficionado 🍨• Alum of MSU @vsicmb

[Aarsh M. Dabhi @aarshmd]

#BuildWetLabs

[Andrea Volpini @cyberandy]

The next revolution will be OI; Organoid Intelligence.
Don’t build data centers. Build wet labs.
Intelligence will start growing.

[Aarsh M. Dabhi @aarshmd]

Thanks for such an Insightful Summary!! 🤩

[William A. Wallace, Ph.D. @WilliamWallace]

Your brain and immune system are not separate. They speak the same language and they constantly regulate each other.

neurons and immune cells form a single, integrated network sense stress, injury, infection, and social cues in real time.

🔵 Neurons don’t just transmit thoughts
They actively shape immune behavior using neurotransmitters, neuropeptides, and electrical signals that influence immune cell migration, activation, and suppression.

🟣 Immune cells talk back to the brain
Cytokines, chemokines, and immune-derived signals directly alter synaptic function, plasticity, mood, motivation, pain perception, and cognition.

🟡 Stress rewires immunity
Psychological and social stress activate neural circuits that mobilize monocytes, neutrophils, and T cells, shifting inflammation throughout the body and brain.

🟢 Microglia are the translators
They integrate neural input with immune signals, shaping learning, memory, behavior, and vulnerability to neurodegeneration.

🔴 This cross-talk spans the entire body
From meninges to gut to vasculature, neural signals coordinate immune defense across space and time, not just during disease, but during normal physiology.

What this means:

• Mental stress can become biological inflammation
• Immune activation can alter behavior and cognition
• Brain health depends on immune regulation
• Disease emerges when communication breaks down

The nervous system and immune system are not rivals.
They are co-authors of your physiology.

Ref:
Leuning A, Gianeselli M, Russo SJ, Swirski FK. Connection and communication between the nervous and immune systems.
Nature Reviews Immunology (2025)

[Aarsh M. Dabhi @aarshmd]

@dr_ericberg Tea with Homies! 😎

[Aarsh M. Dabhi @aarshmd]

For researchers, BDNF = Healthy Neurons!!!
which means Happy Researchers!!😃😃
#brain #neurons #Neuroscience #neurobiology #academia #PhDlife

[Louisa Nicola @louisanicola_]

Exercise is a brain drug. Here’s the biology behind it

New review in Frontiers in Molecular Neuroscience breaks down how exercise boosts brain BDNF, the key molecule for learning and memory.

What matters most:

1. Exercise reliably increases brain BDNF, a driver of neuroplasticity and neurogenesis
2. BDNF supports memory, learning, mood, and stress resilience
3. Blocking BDNF signaling removes many cognitive benefits of exercise

How exercise raises BDNF:
4) Neuronal activity increases calcium signaling and gene expression
5) Increased cerebral blood flow activates endothelial BDNF production
6) Muscle and liver release exerkines like lactate, irisin, IGF-1, and ketones that signal the brain
7) Brain BDNF comes from neurons, blood vessels, and peripheral organs working together

Exercise isn’t just movement, it’s a whole body signal that rewires the brain from the inside out.

[William A. Wallace, Ph.D. @WilliamWallace]

Nutritional Neuroscience: Micronutrients in Neurotransmitter Synthesis and Metabolism- A Simple Illustration.

Understanding the complex interplay between vitamins, minerals, and neurotransmitter pathways highlights the foundational role of nutrition in cognitive health and overall well-being.

[Aarsh M. Dabhi @aarshmd]

@kamran4300 Course

[Aarsh M. Dabhi @aarshmd]

@vikasnavaratna Coincidentally, I did that just today! This exact thing!!

[Aarsh M. Dabhi @aarshmd]

@boyar_dad Is that a TVS Gold mechanical keyboard? 😍

[Aarsh M. Dabhi @aarshmd]

@historyinmemes Go to the future and notice all the historical moments... Then come back to the present and try and live through them as they unfold!

[Aarsh M. Dabhi @aarshmd]

@vikasnavaratna Not Today!

[Aarsh M. Dabhi @aarshmd]

@neophyte_writer @urssahu @yakzaf Congratulations Yuvaraju!!

[Aarsh M. Dabhi @aarshmd]

@urssahu @DBT_NBRC @yakzaf @Saleemm_10 @BBAjournals @neophyte_writer Congratulations Sir!

[Aarsh M. Dabhi @aarshmd]

What a whisker-twitching, tail-swishing adventure! #Caturday 😻

[Jeffrey Ⓥ @LiftForever67]

“We don't stop playing because we grow old; we grow old because we stop playing.”

#Caturday #Tag
#CatsLover #CatsOfTwitter

[Aarsh M. Dabhi @aarshmd]

@NidhiKrishnaS @joshiamitabhevo Congratulations🎉

[Aarsh M. Dabhi @aarshmd]

@HariniSridhar3 Arianna looks the calmest of the lot😃
While Apollo seems full of orange cat energy😄

[Aarsh M. Dabhi @aarshmd]

@HariniSridhar3 What are their names? 😃

[Aarsh M. Dabhi @aarshmd]

@CatWorkers I hope showing this hardworking cat's picture will motivate my cat to turn in the work before the due date!! 😜😜

[Aarsh M. Dabhi @aarshmd]

@FreakyTheory Zorro

[Aarsh M. Dabhi @aarshmd]

@MikaelPalner @kwanalexc Done👍🏼