Aaron Cypess

#BATman; Gen X; beta3-AR

[Aaron Cypess @acypess]

Finally AI does something good for Gen X. Bra-vo!

[Growing Up Retro @GrowingUpRetro]

The A-Team saves the day.

[Aaron Cypess @acypess]

Capital Weather Gang Leaving The Washington Post, Returning To Independent Roots - The MoCo Show https://t.co/jZIdKxYQQl
The Capital Weather Gang is by far the best place to get accurate, nuanced forecasts as well as sophisticated analyses. Good luck @capitalweather!

[Farooqi Lab @Farooqi_Lab]

In a paper just published in @sciencemagazine, we teamed up with @teichlab to construct the most detailed atlas to date of hormone production and action in humans at cellular resolution. (1/8)

Link: https://t.co/5iPOCq9yfu

[The Nobel Prize @NobelPrize]

The first letter of the genetic code was cracked #OTD in 1961 at 3am by Marshall Nirenberg (right) and Heinrich Matthaei (left) at the @NIH.

Nirenberg shared the 1968 medicine prize with Har Gobind Khorana and Robert Holley for their work on the genetic code.

[Aaron Cypess @acypess]

Great news from the Krashes and Lutas groups.atnthe NIH

[Michael Krashes @michael_krashes]

https://t.co/a3lsk75czW

[On This Day in Simpsons History 🇺🇦 @dailysimpsons]

33 years ago today, Krusty the Clown was forced to replace Itchy & Scratchy with Worker & Parasite.

“Krusty Gets Kancelled” first aired on May 13, 1993.

[Aaron Cypess @acypess]

We're looking forward to using the CCT as soon as it opens!

[Tim Sloan @TimSloanDC]

The Capital Crescent Trail has its first layer of asphalt between @PurpleLineMD Bethesda and Connecticut Avenue stations. Between the tracks and trail are 3 styles of fence; wire mesh, acrylic panel & precast. #CCT #BikeDC #PurpleLineMD #purplelineprogress @WABADC @purplelinenow

[Adipose Biology Conference @AdiposeBiology]

🚨 Don’t miss #ABC2026!
⏳ Early Bird ends June 1! Last chance for the best price!
👥 Group discounts available
🎟️ https://t.co/O77QARGOm7
Join us in Montréal 🇨🇦 (Oct 7–9) for cutting-edge adipose biology, metabolism & obesity research🔥
@SableSys @kazaklab @beaudrj @sung4400

[Aaron Cypess @acypess]

Thanks Lawrence! I'm looking forward to the conference

[Lawrence Kazak @kazaklab]

Speaker Spotlight: Aaron Cypess @acypess.
Join us for the 2nd annual @AdiposeBiology Conference in Montreal🇨🇦, Oct 7-9, 2026, to hear from this world expert in human BAT biology!

Register before the early bird deadline at: https://t.co/kbll9EWR9r

#ABC2026 @McGillGCI @NIDDKgov

[Aaron Cypess @acypess]

Magnificent, tour de force work by @TimoMueller_IDO and colleagues.

[Timo Müller @TimoMueller_IDO]

This one was a bumpy ride, but the product is awesome. 💪 Thanks to all the collaborators, like @seeleyrj , T. Horvath, P. Scherer, @Z_GerhartHines @JCampbellLab, M. Tschöp, R. DiMarchi, P. Knerr, J. Douros. Kudos to Liskiewicz & Novikoff

https://t.co/ul1EgCNYqY

[Aaron Cypess @acypess]

Cheers for the #BATteam! I am grateful to work with such talented and generous scientists. #KellyLong #CherylCero #SaharaAli #NhuquynhNguyen #AdrienneGuarnieri #JuHeeKim #JurgenHeymann #MabelTong #SominLee

[ASCI @the_asci]

@acypess @NIH @NIDDKgov Behind the scenes with the Cypess lab: preparing samples and analyzing data.

[JCI insight @JCI_insight]

@acypess @NIH @NIDDKgov BMP7 treatment increased basal and stimulated cellular bioenergetics in human white preadipocytes (hWAs) after 7 or 30 days of BMP7 exposure. Oxygen consumption rate (OCR): https://t.co/dZ8KJIMmAl

[ASCI @the_asci]

@acypess @NIH @NIDDKgov BMP7 treatment increased basal and stimulated cellular bioenergetics in human white preadipocytes (hWAs) after 7 or 30 days of BMP7 exposure. Oxygen consumption rate (OCR): https://t.co/EPRpXJji4g

[JCI insight @JCI_insight]

Can we convert white adipose tissue from energy storing to energy expending? Introducing a new therapeutic strategy to treat obesity-related #MetabolicDisease👇
https://t.co/U7VBvXKt7k

Aaron M. Cypess @acypess & team @NIH @NIDDKgov treated human white adipocytes with specific bone morphogenetic proteins (BMP4 or BMP7), showing transition to distinct “tan” adipocytes with expanded energy-expending capabilities.

[ASCI @the_asci]

Can we convert white adipose tissue from energy storing to energy expending? Introducing a new therapeutic strategy to treat obesity-related #MetabolicDisease👇
https://t.co/e2Gw5m6dDu

ASCI member Aaron M. Cypess @acypess & team @NIH @NIDDKgov treated human white adipocytes with specific bone morphogenetic proteins (BMP4 or BMP7), showing transition to distinct “tan” adipocytes with expanded energy-expending capabilities.

[Echoes of War @EchoesofWarYT]

He won the Civil War, broke the Klan, went bankrupt at 62, got terminal throat cancer, and wrote one of the greatest books in American literature in the final year of his life. He finished it 5 days before he died.

Ulysses S. Grant was born 204 years ago today.

His name wasn't even Ulysses S. Grant. He was born Hiram Ulysses Grant in Point Pleasant, Ohio on April 27, 1822. The congressman who nominated him to West Point wrote down the wrong name. Grant kept it. The "S." stands for nothing.

He hated his father's tannery and loved horses. Graduated 21st of 39 at West Point. Fought in the Mexican-American War, then came home convinced it was an unjust war designed to expand slavery. He later said he believed the Civil War was divine punishment for it.

He married Julia Dent in 1848, into a slave-owning Missouri family. His abolitionist father refused to attend the wedding. In 1859, broke and desperate, Grant freed the one enslaved man he'd briefly owned instead of selling him. He could have gotten a year's wages.

In the Civil War he became what no other Union general was: relentless. Vicksburg (July 4, 1863) split the Confederacy in half. Lincoln then gave him every Union army. His Appomattox surrender terms: officers kept sidearms, men kept horses for spring planting, no one prosecuted.

As president (1869 to 1877) he did something no president would do again until LBJ: used federal troops to crush the Ku Klux Klan. He suspended habeas corpus in 9 South Carolina counties, prosecuted Klansmen before predominantly Black juries, and broke the first Klan.

His presidency was also rocked by scandal: Black Friday 1869. Crédit Mobilier. The Whiskey Ring. Belknap. Grant himself never took a dime. He was just disastrously loyal to corrupt friends. The pattern damaged his reputation for a century.

After the White House, he toured the world for 2 years. Dined with Queen Victoria. Met the emperor of Japan. Then in 1884, a Wall Street partner named Ferdinand Ward ran what we'd now call a Ponzi scheme. Grant was wiped out. 62 years old. Penniless.

Weeks later he was diagnosed with terminal throat cancer. Mark Twain offered to publish his memoirs. Grant wrote in agony, sometimes 50 pages a day, racing the disease to leave Julia an inheritance. He finished the manuscript July 18, 1885. He died July 23.

The book made Julia $450,000, about $14M today. It's now considered one of the finest memoirs in the English language. For decades historians ranked Grant a failure. Since 2000 he's jumped 13 spots in the C-SPAN survey, the biggest rise of any president.

Happy birthday, General 🇺🇸

[Greater Greater Washington @ggwash]

You could ask five residents what Silver Spring’s boundaries are and receive five different answers: https://t.co/vwq1cBov2o

[Yu-Hua Tseng @tsengyuhua]

How does acute hormonal signaling reshape 3D genome? 🧬Using multi-omics approach, we show that acute β3‑adrenergic signaling rapidly rewires 3D chromatin via an SRCAP–H2A.Z axis to activate thermogenic programs. H2A.Z loops overlap obesity‑associated SNP https://t.co/kTGuGS8BIp

[Aaron Cypess @acypess]

@kazaklab @Nature Elegant work Lawrence! Congratulations to the entire team

[Aaron Cypess @acypess]

@ATRightMovies Stalag 17 for its genre