(1/8) Thrilled to reveal the results of the Codebook Project, an international effort to identify accurate DNA-binding motifs and genomic binding loci for the >300 uncharacterized human transcription factors (TFs) https://t.co/6ZagOeftaX
Super excited to finally share the results of a massive effort with @ProfTimHughes to characterize the intrinsic sequence binding specificities of human transcription factors, led by @ArttuJolma, @ahcorcha, @AliFathi125, Ally Yang, and Kaitlin Laverty https://t.co/loj9xRic97 1/n
GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors (Jolma et al., 2024) https://t.co/A7847MTFoB
▶️TFs possess sufficient intrinsic specificity to independently delineate cellular targets
1/4 Pleased to share our latest paper online today @stemcellreports :
Edaravone/Radicava is used to treat ALS. Here we report our unexpected discovery that Edaravone targets cancer stem cells/csc in glioblastoma/GB. Edaravone binds NLE1 suppressing Notch signalling. Gene exp
Let’s be serious for a moment and realise that using the number “over 30,000” Palestinians being killed is, at this point, an outright lie and only helps Israeli propaganda machine.
It was over 30,000 in November. It is over 100,000 now and growing.
In court today, the SPVM spoke against McGill’s request for an injunction against the Gaza solidarity encampment, arguing police discretion is essential and they aren’t the private security force of the university.
You know how hard it is to make the SPVM look reasonable?
Remember Canada, for more than 160 years, had a state-sponsored "residential school" system that was designed to eradicate the language and culture of the country's Indigenous population.
Birds of a settler colonial feather flock together.
Today, @WHO received notification from the Israel Defense Forces that we should remove our supplies from our medical warehouse in southern Gaza within 24 hours, as ground operations will put it beyond use.
We appeal to #Israel to withdraw the order, and take every possible measure to protect civilians and civilian infrastructure, including hospitals and humanitarian facilities.
[updated 21:40]
Doctors Without Borders calls on the Canadian Government to do more than just remember healthcare workers and patients in #Gaza when it is too late.
Canada needs to take action to uphold our shared humanity by demanding an immediate ceasefire. https://t.co/EetHBXcH7N
🔊 One of our staff recounts the moment Israeli forces opened fire on a clearly-marked MSF convoy in #Gaza, killing two people.
We have asked the Israeli authorities for a formal explanation and we call for an independent investigation into this attack.
Doctors Without Borders convoys attacked in #Gaza all elements point to the responsibility of the Israeli army.
We call for an independent investigation to establish the facts and the responsibilities.
https://t.co/2QAYUUetne
Henry Kissinger, one of the world’s most notorious war criminals, has finally died. Let’s take a look back and remember him for all the things he did: 🧵👇
PSAC has pledged $50,000 for humanitarian relief in Gaza as the conflict continues to escalate. More than half of Gaza’s population has been displaced and over 14,000 Palestinians have been killed. Read more: https://t.co/s4GAbjvzfU
Raising Voices for Justice 📣✊: Join us in supporting Palestinian students and allies at McGill. This email template is your tool to reach out to the Provost and Principal, advocating for a campus that stands with Palestinian liberation and solidarity. 💌🕊️ #StandWithPalestine