Andrew Jaffe

VP, Head of Data Sciences at @NeumoraTx. Computational biologist, data scientist across #transcriptomics #epigenomics and #psychiatricgenetics. Tweet are my own

[Barack Obama @BarackObama]

USAID has been fighting disease, feeding children, and promoting goodwill around the world for six decades. As this article makes clear, dismantling this agency would be a profound foreign policy mistake - one that Congress should resist. https://t.co/MSsgZ82QbX

[Andrew Jaffe @andrewejaffe]

@RobertLKruse @AppleHelix that's called "placebo lead-in" and somewhat common

[Andrew Jaffe @andrewejaffe]

@shyam_lab @lpachter I would also guess reporting ' # significant at p < x' eg a fixed pvalue threshold would be less pronounced since fdr /qvalue is more sensitive to small shifts in pvaluesl distributions

[Neumora @NeumoraTx]

We are pleased to share that we have initiated a Phase 1b clinical study with NMRA-511 in #Alzheimers Disease agitation. Read more: https://t.co/znHXoGRvqq $NMRA

[Andrew Jaffe @andrewejaffe]

@raungar nice paper! was diff expression impacted at all by choice of genome build, eg of t-stats comparing pairs of tissues to each other? its not clear expression counts should be comparable across different references (as you showed), but like blood vs muscle should overlap more...

[Andrew Jaffe @andrewejaffe]

@martinowk @LieberInstitute Congrats! Great news and well deserved

[Andrew Jaffe @andrewejaffe]

@alexisjbattle @JHUBME @JohnsHopkins @HopkinsEngineer Congrats, well deserved!

[Keri Martinowich @martinowk]

We have several open research assistant/associate positions on our extended team (me, @kr_maynard, @CerceoPage). Projects are generating transcriptome-scale maps in various human 🧠 regions to understand spatial gene expression in neuropsychiatric & neurodevelopmental disorders

[Andrew Jaffe @andrewejaffe]

@kr_maynard @ACNPorg @martinowk Congrats! We missed you at the annual meeting!

[Keri Martinowich @martinowk]

Big congratulations to all the new Associate Members, but seeing your former trainees on that list is extra special - huge congrats @kr_maynard - so glad to have you in @ACNPorg as a member! We are lucky to have you! #ACNP2023

[Andrew Jaffe @andrewejaffe]

@martinowk @ACNPorg @Dr_Weinberger @LieberInstitute Congrats! Well deserved!!

[Sang Ho (Sangho) Kwon @sanghokwon17]

Thrilled at my FIRST blog post about #Alzheimers https://t.co/1XuOJigtEH & BIG news about our paper officially published in @GENBiotechJrnl spatial-omics issue https://t.co/SMFwgihrk1
Huge Kudos to all coauthors, mentors, & supporters @LieberInstitute @BCMB_JHMI @10xGenomics🙌🙌

[Neumora @NeumoraTx]

We have been working hard this year! Our annual company research poster session offers team members the opportunity to share their work with cross-functional colleagues & showcase their achievements. We had a great afternoon discussing the innovative projects teams are advancing.

[Andrew Jaffe @andrewejaffe]

@seankross @jtleek wait is @jtleek on Hot Ones?

[LIBD rstats club @LIBDrstats]

Check out our latest blog post 👀:

"Introduction to #BiocMAP" by Nick Eagles for aligning 🧩 and preprocessing whole genome bisulfite sequencing data

#WGBS #rstats @bioconductor @nextflowio

📜 https://t.co/n7YXFi2yep

https://t.co/tq4HF71c6P

[Andrew Jaffe @andrewejaffe]

It's been a great journey so far! Been a privilege being here 3 years now!

[Neumora @NeumoraTx]

Today we celebrate becoming a public company, trading on @Nasdaq under the symbol $NMRA. This marks an important step in our journey to confront the global brain disease crisis by redefining neuroscience drug development to make a difference for patients. #IPO

[Andrew Jaffe @andrewejaffe]

@LHSanders14 @DukeHealth @DukeMedSchool super interesting paper! could you possibly clarify the interpretation of the various y-axes of "# lesions per 10kb" in many of the figures? they seem scaled to 1 but its unclear how exactly (and makes it kind of hard to compare across cohorts). thanks!!

[Andrew Jaffe @andrewejaffe]

@martinowk @rodriguez_lion Congrats! Great job!

[Andrew Jaffe @andrewejaffe]

@Matthew_N_B @NeumoraTx!!

[Andrew Jaffe @andrewejaffe]

@MeganDuffyPhD 8ig9999m99??9