Alice Grey

Inmunologist. Opinions my own.

[Michael Makris @ProfMakris]

Rituximab refractory or intolerant immune TTP cases are very difficult to manage. Paper in @BrJHaem from France suggest that Daratumumab is a reasonable therapeutic option. https://t.co/L42R79apMg #TTP #daratumumab

[NEJM @NEJM]

A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission. Full correspondence: https://t.co/fiQJZuoxvD

[Prof Kirsten Perrett @KirstenPerrett]

Thank you for your inspiring visit to MCRI @alex_fsantos!

Our @NACEresearch, @CRE_CFAR and @MCRI_for_kids Allergy Flagship early-mid career researchers gained so much from your insights.

#Allergy #AllergyResearch #ASCIA2024

[Sanam Loghavi, MD صنم لغوی 🔬🧬 @sanamloghavi]

Congratulations to the authors 4 finally putting this decade-long ❓ to rest.
@NatureMedicine
We can all sleep better (or worse 😬) tonight, knowing CH causes atherosclerosis & not the other way around.
That’s some pretty “determinate��� potential, I’d say 😉
TET2> DNMT3A & of course ⬆️ VAF >⬇️ VAF💡

https://t.co/g7sx2aaoSR

#hemepath #leusm

[Waggoner Lab @LabWaggoner]

NLRP3 inflammasome activation in circulating myeloid cells by human RAC2 GOF variants linked to rare immune disorders @JExpMed @lauboye
https://t.co/AGFYhZTmJh

[Anna-Lena Neehus @ALNeehus]

1/ Exactly one year after my PhD defense, I am very excited to share with you the last chapter of my thesis published today in @Nature about humans with inherited TNF deficiency: https://t.co/qzsRqPC3pU.

[ACAAI @ACAAI]

Neffy epinephrine nasal spray was approved by the FDA today. This provides the first epinephrine product for treatment of anaphylaxis that does not require an injection. Read the FDA announcement https://t.co/JqiVZS6K37

[Alice Grey @ausimmdoc]

Long-Term Effectiveness and Discontinuation of Dupilumab in Patients With Atopic Dermatitis https://t.co/VoMtfzpWxI

[Luis Caminal @caminalm]

Efficient detection of somatic UBA1 variants and clinical scoring system predicting patients with variants in #VEXAS syndrome https://t.co/w0f8LRv4ov

[Journal of Allergy and Clinical Immunology @jacionline]

Read a review of allergic manifestations of inborn errors of immunity. It highlights patterns of allergic disease linked to disturbances of specific molecular pathways and provides examples of precision treatments that target these TH2-driven processes. https://t.co/90YSyf7Bb1

[Samuel Hume @DrSamuelBHume]

The 10 biggest medical research papers from this week (in my opinion!)

1. The mTOR inhibitor, Rapamycin, extends lifespan in healthy mice, as does the MEK inhibitor, Trametinib

Combining both together boosts mice lifespan by ∼30%

https://t.co/Oa7QsZ8vMg

🧵

[Juan C Ivancevich MD @Aller_MD]

#Allergenic potency of various #foods of mammalian origin in patients with #α-Gal syndrome: even processed mammalian #meat constitutes a risk and #dairy products show the lowest risk.
https://t.co/oD2smeRcco

[ILLIASUL IBAD @IlliasulK]

Management of APS -2023
#APS
#Rheumatology
#Sullysrounds

[Rockefeller University @RockefellerUniv]

Two kids with HSV-1 encephalitis were found by @casanova_lab to have rare mutations that indirectly allowed the virus to enter their brain cells, demonstrating how protein deficiencies and mutations can facilitate brain inflammation via viral infection. https://t.co/cJvh6EE8Et

[Rheuma Doc @LastManStand85]

Systematic review for Rx of calcinosis. Remains a major challenge in patients with #SSc.Several💊 have been tried with variable results.None have regulatory approval.Small studies,no validated outcome mesures & needs prolonged obvservation #Rheumatology #MedTwitter(L.Chang et al)

[Alexandra Santos @alex_fsantos]

Check our latest paper on immunomodulatory treatments for IgE-mediated food allergy - an important and independent systematic review of the literature and metanalysis to inform the new upcoming clinical guidelines from EAACI @EAACI_HQ @EAACI_JM @KingsCollegeLon @EvelinaLondon

[Sudarshini Ramanathan @darshi_r]

In selected patients with refractory high risk myasthenia gravis, cyclophosphamide resulted in rapid remission induction, corticosteroid reduction & long-term freedom from recurrent injectable therapy- check it out @JNNP_BMJ @syd_health https://t.co/NbkrL6Vspf

[AAAAI @AAAAI_org]

For people with fire ant allergy, stings may cause a life-threatening reaction called anaphylaxis. Symptoms may include itching and hives, swelling in the throat or tongue, difficulty breathing, dizziness, stomach cramps, nausea or diarrhea. #FireAnts
https://t.co/MsmFgNUNfh

[EnvisionRheumat @ERheumat]

#EULAR2024
New EULAR recommendations for managing systemic sclerosis (SSc) are here! Let's break down the key points for effective patient care. 🧵
RP: CCB ➡️ PDE5i➡️ IV iloprost
DU: PDE5i/ IV iloprost
DU Prevention : Bosentan

[saori abe inoue @ori_114]

#Pregnancy is of course one of the important aspect in #lupus 🦋🤰🦋
👉Obstetric complications
👉importance of international collaboration evidence
👉🔑drug HCQ‼︎‼︎

Overall wonderful talk🥹❤️👏
Recommend watching via YouTube📺
#EULAR2024
アツイ~🔥!!