Dark Bio whitepaper is out!
We're building a system in which a person's health data, their genome most of all, no longer has to live with a custodian to be useful. A system, where data does not move, rather stays on a small device the owner holds.
JUNE 2028.
The S&P is down 38% from its highs. Unemployment just printed 10.2%. Private credit is unraveling. Prime mortgages are cracking. AI didn’t disappoint. It exceeded every expectation.
What happened?
https://t.co/JzzwCrbJgS
“abolish capitalism!”
cool. who grows the food???
no seriously—who’s out there at dawn breaking their back in the dirt, fixing broken irrigation lines, replacing a tractor axle in 110° heat—for free? because you think profit is mean?
who mines the lithium for your laptop, the cobalt for your EV battery, the iron for your train rails? who refines it? who ships it? who builds the ships? who insures them when they catch fire in the middle of the ocean?
who unloads the containers at the port? who drives the truck across 4 states? who services the diesel engine at the roadside stop in Nebraska when it breaks at 3am?
who keeps track of inventory, repairs the refrigeration system, updates the software, cleans the floors, builds the shelves, trains the workers, manages the risk, pays the legal fees, replaces the lightbulbs, handles the theft, the overtime, the breakdowns, the lawsuits?
who coordinates all of this across time zones and continents without profit?
you think the whole supply chain is just gonna keep running because everyone suddenly caught a case of the warm fuzzies???
you think people are going to wake up and go do hard, thankless, physical labor for vibes?
capitalism doesn’t work because people are good. it works because people are selfish and it figured out how to harness that into infrastructure. it’s the only system that survives human nature without needing to rewrite it
you kill profit, you kill production. you kill production, you kill logistics. you kill logistics, and suddenly it’s day four of your anti-capitalist utopia and the shelves are empty, the power’s out, the pharmacy’s closed, and nobody knows how to fix a fucking thing
anti-capitalism isn’t a philosophy. it’s a death wish dressed up as a virtue signal
it’s the aesthetic of rebellion powered by an iPhone, subsidized by Uber Eats, and resting on 400 years of industrial infrastructure you take for granted because you’ve never built a single useful thing in your life
you’re not oppressed. you’re just ungrateful
and the second you get your little no-profit revolution, you’ll find out exactly how long society runs on vibes: about three days, give or take—then the generators fail and you’re boiling rainwater so you can heat up your shitty powdered food
With that said, I don't think its a good thing that Apple researchers tilt to the skeptical. How can you innovate if the core thinkers/leaders in your organization are non-believers? Might explain why Apple may be failing to lead in this important area.
Gm, I stopped talking about this when I began considering it viable.
Concerns around being public no longer apply.
Parts for substructural element prototype and 30 ton press in mail. First destructive test soon. Might raise VC.
Will be the next AT&T, the next "space sector."
most of the world starts making sense when you realize that modern leftists don’t hate oppression, they hate excellence.
nothing enrages them more than competence because it exposes their own mediocrity. they aren’t driven by compassion, only resentment for what they can never be.
their entire ideology is a war on hierarchy, not because hierarchy is unjust, but because they know they’ll always be at the bottom unless they can manipulate the system.
a simple but great world model: the good is whatever leftists oppose
People often ask me why they should read this book.
@homsiT said it best: “This book is a force multiplier for personal agency.”
If you read it, you’ll realize that pessimists and doomers of all kinds are simply wrong.
People who seek to curtail your freedom to pursue the ends they consider “good” are also just wrong.
Progress is neither guaranteed nor automatic—so blind “optimists” are also wrong.
You will leave with a robust understanding of why the future depends on the choices people make today—and ultimately, why you, as an individual, matter in the cosmic scheme of things because you possess the agency to create the future you want for yourself.
“Every human is a lottery ticket bet on the future of the species.” — @naval
If we continue to solve problems, we will come to dominate the entire cosmos.
All you need to do is take nothing on faith, question every piece of knowledge, and remain open to having your own ideas criticized and improved upon. That’s the only way to make an unending stream of progress and ensure that anything good can ever happen.
The FDA approved suzetrigine (brand name Journavx), the first new pain medication with a novel mechanism in over 20 years, marking a breakthrough in non-opioid painkillers.
The drug works by blocking specific pathways in nerve cells that use sodium ions to transmit pain signals to the brain.
These pathways, called sodium channels, act like gates that open and close to let sodium flow through nerve cells, which is how pain signals travel through the body.
While older drugs like lidocaine blocked all sodium channels throughout the body, suzetrigine specifically targets just one type (called NaV1.8) that is primarily found in pain-sensing nerve cells.
This selective targeting allows it to provide powerful pain relief without affecting other parts of the body, avoiding the side effects and addiction risks associated with opioids.
In clinical trials, patients reported pain relief without the grogginess or nausea typically experienced with opioids.
The approval represents an alternative to opioid prescriptions for acute pain management - particularly important as doctors seek effective painkillers that don't carry risks of dependency or overdose.
Previous attempts to develop such non-opioid painkillers have largely failed, with many drugs either proving ineffective or causing unwanted side effects.
Tesla's Mezcal alcoholic spirit will restock in the U.S. tomorrow, December 12th, priced at $450.
"Our limited-release Tesla Mezcal is floral, delicate and spicy with earthy aromas and hints of lime, green apple and spice followed by smoky notes. Finishes with soft tuberose, jasmine and chamomile. Mouthfeel is balanced, yet strong with light bitter notes at the end."
Shop: https://t.co/RxdWBEnXfJ