New @CellReports paper by @andrewaguirremd@DanaFarber_Hale
Integrative genomic identification of therapeutic targets for #PancreaticCancer
https://t.co/HM7IzEtJH5
VERY GOOD use of public datasets (DepMap, CCLE, TCGA, GTEx) to identify cell intrinsic & cell surface dependencies
A beautiful and important @CD_AACR study by Sandra Misale dissecting the distinct oncogenic signaling of RAS G12 and Q61 mutations and how they impact responses to therapy. https://t.co/kwgkmxQKdh
Always great to hear the original RAScal @cjder23@derlabunc talk about KRAS & KRAS inhibitors. Thanks to Channing and his team for putting together such great overview slides. As of March 2025, there are 45 inhibitors (!) & 160 clinical trials. Absolutely amazing.
@DavidHongMD
Check out this #protocol by @MatheaGeraud@AgneseCristini@LaraFernandezMz@AndreaCAjello@SIGNATHER et al for single-cell analysis of DNA double-strand break production and repair in cell-cycle phases by automated high-content microscopy: https://t.co/nrGPTux5lC. 🔬🧬Research in Cell Reports:
https://t.co/NTPnZ7lsfh
Save the date! On March 25th, We'll dive into Nanofluidic tools for studying DNA repair with Fredrik Westerlund @FWesterlundand and R-loops & genome instability with Sidrit Uruci @UruciSidrit & Agnese Cristini @AgneseCristini.
Today I had the honour giving a seminar @Stanford_ChEMH@Stanford hosted by Prof. Laura Dassama. It was a wonderful experience with scientific discussions, visit of the campus and a great dinner!! Thanks to Laura and her lab members for their kindness! That was a great week!
Very glad to have presented my PhD work and to have heard such inspiring talks at @CellSymposia focused on drugging the undrugged in San Francisco 🌉
A big thanks to my supervisors for giving me this opportunity
@BeryNicolas@CordelierPierre@crctoncopole#CSChembio2024
Looking forward to speaking @CellSymposia
#CSChembio2024 organized in San Francisco next week! I will talk about "Targeting hard-to-drug proteins in cancer with potent intracellular biodegraders", including the work of @MarieSorbara in the lab of @CordelierPierre@crctoncopole
📣 We are hiring! Interested in KRAS inhibition and resistance in lung cancer? We are looking for a POSTDOC for an AECC-funded project. The position will be available for 3 years, incorporation in January 2025. For more information see: https://t.co/NbbyyrhlvG
Free scientific illustrations for biologists! 😍
@NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations!
all freely available in the public domain.
Retweet and spread the message!
https://t.co/p1bD1kxO7H
There is a new tool on BioIcons to turn any protein (in PDB format) into a 2D vector illustration in SVG format. You can upload any PDB file or import from PDB, AlphaFoldDB or ESMFoldDB. Feedback welcome :)
https://t.co/grMysO8JV5
📚💡 ELiAH: the atlas of E3 ligases in human tissues for targeted protein degradation with reduced off-target effect
https://t.co/WqRHO9mR6M
#TPD#Targeted_Protein_Degradation
It is out! #NanoPlex is the universal strategy for multiplexing any immunofluorescence using erasable #nanobodies from @_NanoTag_. We showcase easy multiplexed STED, STORM, and 21-plex Confocal #Microscopy. Published in @NatureComms here: https://t.co/mCtlJsKCRR